摘要：Objecti.e: The purpose of thi. study was to evaluate the relati.nshi. between serum concentrati.ns of relaxi. and soluble CD163 wi.h cervi.al length and preterm deli.ery i. women wi.h previ.us spontaneous preterm deli.ery. Study desi.n: Si.ty-one of 69 pregnant women wi.h a previ.us spontaneous preterm had serum relaxi. and soluble CD163 measured at week 16(range, 12-25 weeks). End poi.ts were cervi.al length and gestati.nal age at deli.ery. Results: Of the 61 women, 26%had > 1 previ.us spontaneous preterm deli.ery; 84%were black; 87%were unmarri.d; 13%were smokers, and 39%were deli.ered before 37 weeks of gestati.n. Nei.her relaxi.(medi.n, 368 ng/L; range, 83-1493 ng/L) nor soluble CD163(2.4 mg/L; range, 0.86-6.85 mg/L) correlated wi.h cervi.al length or gestati.nal age at deli.ery. Black women had hi.her relaxi. levels(436 vs 205 ng/L; P=.002), but soluble CD163 levels were si.i.ar among raci.l groups. Conclusi.n: Relaxi. and soluble CD163 measured at 16 weeks of gestati.n are not cli.i.ally useful predi.tors of short cervi.al length or preterm deli.ery i. women wi.h a previ.us spontaneous preterm deli.ery.