摘要：Dear Editor,Since the declaration of COVID-19 as a global pandemic on March 11,2020,this pandemic has been circulating for 17 months throughout the world,leading to more than 200 million infections and nearly 4A million deaths as of August 15,*** pathogen of COVID-19 is a novel coronavirus named SARS-CoV-2,which shares ～79％ genome sequence identity with SARS-CoV.1 At the early stage of the COVID-19 outbreak,SARS-CoV-2 caused great panic in the hardest-hit areas due to its high transmissibility and *** fight the COVID-19 crisis,drug repurposing was immediately pursued in order to find potential *** now,though some treatment options are available,there still lack effective antiviral *** is considered as the best way to control this global pandemic,but the emerging SARS-CoV-2 variants pose a great challenge to the protective efficacy of the existing ***,in the long run,finding an effective antiviral medication against the SARS-CoV-2 infection is a pressing need.