摘要：静息态功能磁共振成像(rsfMRI)测量人脑自发神经活动,安全可靠且易于操作而大规模实施,用于揭示认知活动与精神疾病神经影像变化,已成为人口神经科学收集大脑表型信息而倚重工具之一.高信度是rsfMRI测量个体差异的基本要求,但当前rsfMRI测量的信度水平偏低(多低于0.6),不同研究和不同测量指标信度差异较大,脑网络间信度存在较大异质性.当前,rsfMRI信度研究在领域内渐备受关注,如何开展rsfMRI信度研究亟待领域规范和指南.通过描述人口特征学、样本规模和测量安排三个信度研究维度对rsfMRI信度的影响,本文系统介绍rsfMRI信度研究进展,据此提出人口神经科学rsfMRI信度研究指南:基于人口神经科学规范化建模进行rsfMRI测量标准化,提供rsfMRI研究测量指标的信度信息;扩大研究样本量、高效安排扫描间隔和延长扫描时间;优化扫描参数、减少扫描噪声和进行标准化扫描;用标准化程序预处理静息态功能像数据,有效化计算和分析方法.

摘要：Brain growth charts and age-normed brain templates are essential resources for researchers to eventually contribute to the care of individuals with atypical developmental *** present work generates age-normed brain templates for children and adolescents at one-year intervals and the corresponding growth charts to investigate the influences of age and ethnicity using a common pediatric neuroimaging *** accelerated longitudinal cohorts with the identical experimental design were implemented in the United States and *** magnetic resonance imaging(MRI)of typically developing school-age children(TDC)was obtained up to three times at nominal intervals of1.25 *** protocol generated and compared population-and age-specific brain templates and growth charts,respectively.A total of 674 Chinese pediatric MRI scans were obtained from 457 Chinese TDC and 190 American pediatric MRI scans were obtained from 133 American ***-and age-specific brain templates were used to quantify warp cost,the differences between individual brains and brain *** growth charts for labeled brain network areas were *** analyses of cost functions supported the necessity of age-specific and ethnicitymatched brain templates,which was confirmed by growth chart *** analyses revealed volumetric growth differences between the two ethnicities primarily in lateral frontal and parietal areas,regions which are most variable across individuals in regard to their structure and ***-and ethnicity-specific brain templates facilitate establishing unbiased pediatric brain growth charts,indicating the necessity of the brain charts and brain templates generated in *** templates and growth charts as well as related codes have been made freely available to the public for open neuroscience(https://***/zuoxinian/CCS/tree/master/H3/Growth Charts).

摘要：随着工业4.0、中国制造2025、智能制造等发展战略的提出,数字孪生技术被广泛关注,其作为物理对象与虚拟对象的循环映射过程中的关键手段,贯穿流程服务全生命周期。通过对水泥工厂全生命阶段研究,引入数字孪生技术,提出面向水泥工厂全生命周期管理体系,重点研究数字孪生技术在水泥工程智慧建造过程中的特点,包括孪生模型设计构建过程、施工过程信息集成以及在孪生模型的基础上进行施工过程中的数字化管理。为水泥工程数字化、智能化转变提供思路和价值参考。