摘要：冶金行业中,转炉烟气的在线分析普遍采用激光吸收光谱法等单组分气体分析技术,实践中需使用多传感器的组合以同时监测CO、CO_(2)、O_(2)、H_(2)等多组分,分析系统整体的复杂程度和成本高,响应速度慢,逐个传感器的日常校正维护工作量大。为简化在线分析系统的复杂度,提高分析效率,实现炼钢流程的降本增效,首创性的建立了一种转炉烟气中多组分气体实时在线分析的拉曼光谱方法,并首次研制了专用于炉气检测的多组分气体分析系统。通过检测CO、CO_(2)、N_(2)、O_(2)、H_(2)五组分的拉曼光谱特征峰强,对五组分含量进行同时定量分析。检测范围0.1%~100%,检测精密度RSD值均≤0.1%。分析系统中,样气处理模块采用耐高温探头和大功率抽气泵,快速、有效去除进入分析仪的样气中水分和灰尘,保证测试条件稳定;分析模块采用窄线宽532 nm激光器和透射式光谱仪,并通过空间光路设计以提高检测灵敏度,满足气体检测需求。相比于现有的单组分在线分析技术,所提出的多组分检测方法可同时给出五组分的定量结果,不受样气压力、测试条件变化影响,样气前处理难度低,检测准确度高,系统维护简单。N_(2)标准气体的拉曼散射信号特征峰强在24 h内波动≤0.48%。经标准样品验证,该方法检测误差≤0.3%,达到转炉烟气实时检测的需求。该方法不仅在冶金行业有广阔应用前景,还可通过模型扩展以拓展到其他多组分气体实时在线分析监测领域。

摘要：陈皮中的橙皮苷、柚皮苷和辛弗林同时提取的不同提取技术参数的优化。通过正交设计实验研究超声提取与微波提取同时提取橙皮苷、柚皮苷和辛弗林的最佳实验条件。采用高效液相(HPLC)测定提取的橙皮苷、柚皮苷和辛弗林的含量。对于陈皮药材,不同提取方法对3种活性成分的提取率影响较大,微波提取对这3种成分具有最高的提取率。在优化工艺条件下:80%甲醇水溶液,料液比1:200、微波功率300W、微波时间2min,陈皮中橙皮苷、柚皮苷和辛弗林产率分别可达(58.72±0.939)mg/g,(2.12±0.084)mg/g和(3.32±0.086)mg/g。

摘要：圆弧端齿传扭+中心拉杆预紧是一种简单可靠的航空发动机转子连接结构,这种连接方式的一个明显特征是轴向预紧力最终作用在小尺寸、弱刚性轴颈结构的端面上,实际过程会出现预紧力加载损失较大的问题。针对上述问题,该文对弱刚性轴颈结构的工艺加载过程进行了受力分析,建立了预紧力加载损失模型,推导出实际加载预紧力公式并获得加载损失率。以某型端齿连接的转子为研究对象,通过数值仿真和试验测试的方法,对弱刚性轴颈结构的加载损失情况进行了分析和验证,结果表明,弱刚性轴颈结构的预紧力加载损失约为14%~18%,且与实际加载预紧力公式计算结果一致。建议在弱刚性轴颈结构的预紧力设计和试验阶段,充分考虑加载损失情况,并给出必要的加载补偿。

摘要：【目的】分析国外无人机空中交通管理方式及体系架构层级,归纳体系架构设计原则,提出多种UTM架构并给出民用无人机飞行动态传输模式,推动我国无人机产业和低空经济发展。【方法】通过文献法、数据调研法分析国外相关情况,结合我国现状,遵循服务主导、安全聚焦等原则进行体系架构设计。【结果】提出集中式、分散式双层级和三层级UTM架构,明确民用无人机飞行动态传输的多种路径及各部门数据交互方式。【结论】有助于构建适用于我国国情的无人机空管体系架构及标准,为我国无人机产业和低空经济发展提供支持。

摘要：For the chip integration of MEMS(micro-electromechanical system) safety and arming device, a miniature detonator needs to be developed to reduce the weight and volume of explosive train. A Si-based micro-detonator is designed and fabricated, which meets the requirement of MEMS safety and arming device. The firing sensitivity of micro-detonator is tested according to GJB/z377A-94 sensitivity test methods:Langlie. The function time of micro-detonator is measured using wire probe and photoelectric transducer. The result shows the average firing voltage is 6.4 V when the discharge capacitance of firing electro-circuit is 33 mF. And the average function time is 5.48 ms. The firing energy actually utilized by Si-based micro-detonator is explored.

摘要：A successful mechanical property data-driven prediction model is the core of the optimal design of hot rolling process for hot-rolled strips. However, the original industrial data, usually unbalanced, are inevitably mixed with fluctuant and abnormal values. Models established on the basis of the data without data processing can cause misleading results, which cannot be used for the optimal design of hot rolling process. Thus, a method of industrial data processing of C-Mn steel was proposed based on the data analysis. The Bayesian neural network was employed to establish the reliable mechanical property prediction models for the optimal design of hot rolling process. By using the multi-objective optimization algorithm and considering the individual requirements of costumers and the constraints of the equipment, the optimal design of hot rolling process was successfully applied to the rolling process design for Q345B steel with 0.017% Nb and 0.046% Ti content removed. The optimal process design results were in good agreement with the industrial trials results, which verify the effectiveness of the optimal design of hot rolling process.

摘要：In order to design a complex laser resonator with multi-parameters, the method of particle swarm optimization(PSO) algorithm is employed. The parameters influencing the resonator stability and mode size distribution are taken into consideration, and the stability criteria index and the mode size distribution are used as target values. The absolute values of the differences between practical and the target values are set as the fitness function for the PSO. By minimizing the fitness function, a laser resonator with the optimized cavity parameters can be found. The analyses for the design example demonstrate the feasibility and validity of the PSO method in the computer aided design of multi-parameters laser resonator. Applying PSO algorithm in the intelligent design of solid state laser resonators can realize the transition from manual trial-and-error to computer intelligent design of the laser resonators.

摘要：A series of hydrazine and oxadiazole analogs of Sorafenib was designed, synthesized and characterized by proton nuclear magnetic resonance（1H NMR） spectrometry and high resolution mass spectrometry（HRMS）. The anti-proliferative activities of these compounds against human colorectal earcinoma（HCT-116） and human breast cancer （MDA-MB-231） tumor cell lines were evaluated in vitro by MTT method[MTT=3-（4,5-dimethylthiazol-2-yl）-2,5- diphenyltetrazolium bromide]. The bioassay results suggest that most of the synthesized compounds have antitumor potential to HCT-116 cell line compared with MDA-MB-231 cell line. Compounds 8a, 8b, 8d, Be, 9f and 9j competitive with Sorafenib demonstrated antiproliferative activities on HCT-116 cell line.

摘要：假单胞菌属(Pseudomonas spp.)是一类重要的食源性致病菌和腐败菌。噬菌体裂解酶具有高效裂解活性和靶向性等特征,可作为有效控制假单胞菌属细菌的新型抗菌剂。随着组学技术的高速发展,大量噬菌体的基因组信息得到破译,为噬菌体裂解酶生物信息的挖掘提供了数据资源。本研究基于NCBI等数据库,深入挖掘假单胞菌噬菌体裂解酶的理化参数、核心结构域、三维结构等生物信息。结果表明,共筛选获得了81个噬菌体裂解酶序列,此类裂解酶大多为亲水蛋白(80/81),均具有较高的等电点,蛋白总体带正电。在所筛选的裂解酶序列中,共发掘9个保守结构域,分别为Lyz-like super family、yz_endolysin_autolysin、Muramidase、PGRP super family、NlpC/P60、LT-like、Phage_lysis Superfamily、PG_binding_1、PG_binding_3。同源建模分析发现,裂解酶末端α-螺旋上均分布一定的正电荷基团,预测该结构可能赋予其穿透假单胞菌外膜的功能。本研究为假单胞菌噬菌体裂解酶的设计、改造和生产提供理论支撑,为假单胞菌的靶向防控提供重要的数据基础。

摘要：文化创意产业园区承载无形的文化创意,它的物理特征、经济特征、组织特征和社会特征都可以通过虚拟组织实现,文化创意产业虚拟园区作为文化创意产业发展的载体具有可行性,它拓展了文化创意产业发展的空间维度,减少了交易成本,推动了文化创意产业的发展。本文把贝叶斯集体选择模型应用于文化创意产业虚拟园区的入驻企业选择上,提出文化创意产业核心企业参与虚拟园区管理需要解决的若干问题。