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摘要:Recently,in-situ polymerization inside living cells has attracted much attention due to the efficient cellular internalization and elevated drug ***,the lack of tracking of the in-situ polymerization process and the unclear effects of polymerization on cellular functions restrict its biomedical ***,we designed a Y-shaped diacetylene-containing lipidated peptide amphiphile(YDLPA1)with positive charges,which underwent in-situ polymerization initiated by reactive oxygen species in the intracellular *** comparison,zwitterionic YDLPA2 and negatively charged Y-DLPA3 were polymerized in aqueous solution,but cannot polymerize in the intracellular *** polymerized Y-DLPA1 with red fluorescence provides a platform to label cells for long-term tracking *** polymerization reaction induced tumor cell apoptosis,increased cell viscosity and decreased cell motility,which potentially inhibited tumor metastasis and served as a novel antitumor *** work provides a novel strategy to track in-situ polymerization process and modulate cell biofunctions.
摘要:破碎机全液压系统用于驱动回转式剪切破碎机。应用电液伺服比例调速技术和液压节能技术,研制用于回转式剪切破碎机的液压驱动系统,满足回转式剪切破碎机的工作要求。
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