摘要：A series of novel benzofuran-isatin-hydroxylimine/thiosemicarbazide hybrids were designed, synthesized and evaluated for their in vitro anti-TB activities against drug-sensitive MTB H_(37)Rv and MDR-TB isolates as well as cytotoxicity. All benzofuran-isatin-hydroxylimine/thiosemicarbazide hybrids exhibited considerable in vitro anti-mycobacterial activities against the tested three MTB strains, and all of them also showed acceptable cytotoxicity. The most active hybrid 7f was >4.8 and >51 folds more potent than the first line anti-TB agents RIF and INH against both drug-sensitive MTB H_(37)Rv and MDR-TB isolates, respectively. The results demonstrated the potential utility of benzofuran-isatin-hydroxylimine/-thiosemicarbazide hybrids as anti-TB agents.

摘要：为更加准确测量储层岩体力学动、静态参数,归纳两者关系并探讨差异的影响因素,对岩体地下所处条件(即综合考虑围压、孔隙压力、温度和饱和流体的影响)进行了恢复,同步测量了49块不同地区储层岩样的动、静态参数。结果表明:1在原位条件下动、静态杨氏模量相关性好;2对于低渗透储层,动态杨氏模量普遍大于静态,而且随着岩样致密程度的增大差异变大;3针对不同样品,根据物性细分,各自建立动、静态参数图版,大大地提高了相关性和准确性。最后根据中国陆相松辽、鄂尔多斯两个大型盆地低渗透储层样品物性的差异,建立了原位条件下杨氏模量动、静态校正图版,为进一步建立低渗透油气藏岩体力学参数场和地应力场,优化压裂参数设计和提高施工成功率提供较可靠的资料。

摘要：安装在高速运动载体上的雷达高度表 ,其地面回波被一宽带多普勒信号所调制 ,从而使回波表现出新的特征 ,如何提取和充分利用这些特征对于雷达高度表的设计是非常重要的。首先介绍了大地回波宽带多普勒信号模型的建立 ,然后给出了在MATLAB下建立的仿真框架 ,最后对仿真结果进行了初步分析。