摘要：近年来,随着纳米技术的不断发展,多功能纳米复合材料在肿瘤治疗领域得到了广泛应用.因肿瘤的异质性、复杂性以及多样性的特征,使得单一的治疗手段很难达到理想的治疗效果.因此,将多种治疗方式相结合实现肿瘤的联合治疗成为了研究的热点.本文设计了一种新型的纳米治疗平台,在Pt@介孔Au纳米材料(Pt@Au)的表面包覆聚多巴胺(PDA)壳层,并在PDA壳层中负载阿霉素(DOX),在PDA壳层表面修饰葡萄糖氧化酶(GOx)和NH_(2)-PEG_(5K)-***_(2)-PEG_(5K)-cRGD可以与肿瘤细胞中过表达的αvβ_(3)整合素特异性结合,实现纳米治疗平台在肿瘤区域的富集.DOX可以损伤肿瘤细胞的DNA,用于化学治疗.介孔Au和PDA优异的光热性能可以用于光热治疗.GOx可以与肿瘤细胞内的葡萄糖反应生成葡萄糖酸和H_(2)O_(2),实现饥饿治疗.Pt作为常见的类过氧化氢酶可以催化肿瘤细胞内H_(2)O_(2)分解生成O_(2),缓解肿瘤乏氧微环境,促进饥饿治疗.因此,制备的Pt@Au@PDA-DOX-GOx-cRGD具有化疗-光热治疗-自促进饥饿治疗联合治疗肿瘤的能力.

摘要：近年来物联网的快速发展带动可穿戴领域迅速崛起,体域网的出现对可穿戴设备的无线收发提出了新需求:在生物医疗应用中要求收发天线能够适应拉伸弯曲形变.传统天线制作在刚性衬底上,不具有柔性,而且天线在拉伸条件下发生形变,工作频率迅速变化导致性能退化,难以满足柔性系统的需求.本文针对此类需求,在柔性衬底PDMS材料上设计了一款可延展柔性倒F蓝牙天线,通过辐射臂曲流形走线和地平面的分割设计,天线的可延展柔性得以实现.仿真结果显示,设计的天线在保证工作频带完全覆盖蓝牙频段的条件下,X轴向上可做到最大20%的拉伸,Y轴向上可做到60%的拉伸,同时可承受最小曲率半径为8 mm的弯曲.

摘要：To stabilize Ru nanoparticles against sintering is an urgent problem in the utilization of Ru-based catalysts for NH3 *** the present study,we used Ru-containing ZSM-5 as seeds to crystallize ZSM-5,and the resulted Ru@ZSM-5 catalyst is highly resistant against Ru *** to the results of diffuse reflectance infrared fourier transform spectroscopy(DRIFTS)and transmission electron microscopy(TEM)analyses,the average size of Ru nanoparticles is around 3.6 nm,which is smaller than that of Ru/ZSM-5-IWI prepared by incipient wetness *** NH3 synthesis(N2:H2=1:3)at 400℃and 1 MPa,Ru@ZSM-5 displays a formation rate of 5.84 mmolNH3 gcat^-1 h^-1,which is much higher than that of Ru/ZSM-5-IWI(2.13 mmolNH3 gcat^-1 h^-1).According to the results of TEM,N2-temperatureprogrammed desorption(N2-TPD),X-ray photoelectron spectroscopy(XPS)and X-ray absorption fine structure(XAFS)studies,it is deduced that the superior performance of Ru@ZSM-5 is attributable to the small particle size and the ample existence of metallic Ru0 *** method of zeolite encapsulation is a feasible way to stabilize Ru nanoparticles for NH3 synthesis.

摘要：It is a great challenge to develop highly active oxygen evolution reaction(OER)electrocatalysts with superior *** this study,a NiFe layered double hydroxidedecorated phosphide(NiFe LDH@CoP/NiP_(3))was constructed to display satisfactory OER activity and good stability for water splitting in alkaline *** an overpotential of 300 mV,NiFe LDH@CoP/NiP_(3) achieved a current density of 82 mA cm^(-2) for the OER,which was 9.1 and 2.3 times that of CoP/NiP_(3) and NiFe LDH,***,the reconstruction behavior,during which oxyhydroxides formed,was studied by a combination of X-ray photoelectron spectroscopy,Raman spectroscopy,and scanning electron microscopy.A synergistic effect between NiFe LDH and CoP/NiP_(3) was also observed for the hydrogen evolution ***,when NiFe LDH@CoP/NiP_(3) acted as both the cathode and anode for overall water splitting,a high current density of 100 mA cm^(-2) was maintained for more than 275 *** addition,under Xe light irradiation,a solar-to-hydrogen efficiency of 9.89% was achieved for solar-driven water *** work presents the coupling of different active compositions,and can provide a reference for designing bifunctional electrocatalysts.

摘要：在自行设计的小型鼓泡反应器中,以亚氯酸钠溶液作为吸收剂,进行了模拟烟气同时脱硫脱硝实验研究,得到反应的最佳实验条件以及在此条件下同时脱硫脱硝效率.分析了反应产物,推导出了亚氯酸钠溶液与硫氧化物、氮氧化物的反应历程以及总化学反应方程式.利用热力学原理计算出亚氯酸钠溶液同时脱硫脱硝的摩尔反应吉布斯函数、摩尔反应焓变、化学反应平衡常数以及化学反应达到平衡时SO2和NO的分压力.结果表明:亚氯酸钠溶液同时脱硫脱硝是可行的,且可以几乎100%的脱除烟气中的SO2和NO.

摘要：The rational design and construction of inexpensive and highly active electrocatalysts for hydrogen evolution reaction(HER)is of great importance for water ***,we develop a facile approach for preparation of porous carbon-confined Ru-doped Cu nanoparticles(denoted as Ru-Cu@C)by direct pyrolysis of the Ru-exchanged Cu-BTC metal–organic *** served as the electrocatalyst for HER,strikingly,the obtained Ru-Cu@C catalyst exhibits an ultralow overpotential(only 20 mV at 10 mA cm^(-2))with a small Tafel slope of 37 m V dec^(-1)in alkaline *** excellent performance is comparable or even superior to that of commercial Pt/C *** functional theory(DFT)calculations confirm that introducing Ru atoms into Cu nanocrystals can significantly alter the desorption of H_(2) to achieve a close-to-zero hydrogen adsorption energy and thereby boost the HER *** strategy gives a fresh impetus to explore low-cost and high-performance catalysts for HER in alkaline media.

摘要：代冲溪水库重力坝坝基发育23 m宽的断层破碎带,破碎带岩体力学特性较弱,在大坝的施工、蓄水和运行过程中会对坝基的稳定性产生重要影响。基于工程地质条件和岩体力学参数提出了坝基处理的微拱形混凝土塞置换基础方案,并开展了三维有限差分数值模拟计算和坝基F1断层岩石力学参数的敏感性分析。研究得出,在宽大断裂带软基岩体情况下,变形模量差异和断层带的弱承载力导致坝基的不均匀变形现象明显。通过微拱混凝土塞置换之后,蓄水过程坝基承载力及重力坝应力变形均满足要求。由于混凝土塞能够较好的发挥作用,断层破碎带参数的变化对大坝和坝基应力变形影响被削弱。相关研究为跨越宽大断层重力坝的基础处理提供了重要的参考价值。

摘要：车身结构作为安全的基石,对安全性能有着不可忽视的影响,在设计时既要考虑人机及安全性能的平衡,也要考虑到成本及轻量化的需求。顶压作为安全性能的重要一项内容,对侧围系统的结构及材料等有着相当高的要求。文章通过对车顶抗压强度的仿真分析及优化,以达到中国保险汽车安全指数(C-IASI)抗压强度G级评价标准,从而总结全景天幕车型侧围结构的设计关键。结合某车型开发案例,对侧围顶压框架的优化设计,为后续车型的侧围结构设计提供参考。

摘要：交通建筑作为一种重要的公共空间类型,其设计不仅要满足功能性需求,还应承载和传承地域文化价值。因此,研究交通建筑设计中地域文化的应用具有重要意义。通过对地域文化特征的深入分析和探讨,本研究试图在满足基础交通功能的同时,挖掘并融入地域文化元素,进一步丰富交通建筑的文化内涵和视觉效果。研究背景基于多个城市的交通建筑案例,对比分析了利用地域文化元素在交通建筑设计中的实际应用效果,发现地域文化的合理引入可以使交通建筑更好地融入周边环境,增强建筑与土地的连接,同时传递城市特色和历史信息。此外,也发现研究地域文化元素的种类、应用方式和效果的差异性,则可以为今后的交通建筑设计提供参考和启示。

摘要：近年来柔性电子的出现带动了可穿戴设备、医疗电子、柔性显示和物联网等领域的飞速发展.随着柔性电子复杂性的提升,越来越多的功能器件被集成在柔性衬底上,功能器件之间的通信成为柔性电子设计中的重要问题之一.本文针对岛桥结构的柔性电子系统,提出了一种基于蜂窝拓扑结构的片上网络通信架构以及相应的路由算法.相比于传统结构,该架构能够有效地避免局部形变过大导致的互连导线断裂.同时,在面积和功耗方面也有显著改善.相比于Mesh结构的片上网络,本文提出的基于蜂窝拓扑的通信架构减少了46.43%的面积和30.51%的功耗.