摘要：张大千在成都的艺术活动以及离蓉后对成都的思念,表现了他对故乡的一片深情,彰显了其艺术人生的“成都意义”。

摘要：This study investigated the influence of graded Zn content on the evolution of precipitated and iron-rich phases and grain struc-ture of the alloys,designed and developed the Al–8.0Zn–1.5Mg–1.5Cu–0.2Fe(wt%)alloy with high strength and *** the increase of Zn content,forming the coupling distribution of multiscale precipitates and iron-rich phases with a reasonable matching ratio and dispersion distribution characteristics is *** phenomenon induces the formation of cell-like structures with alternate distribu-tion of coarse and fine grains,and the average plasticity–strain ratio(characterizing the formability)of the pre-aged alloy with a high strength is up to *** reveal the evolution and influence mechanisms of multiscale second-phase particles and the corresponding high formability mechanism of the *** developed coupling control process exhibits considerable potential,revealing remarkable improvements in the room temperature formability of high-strength Al–Zn–Mg–Cu alloys.

摘要：Two-dimensional covalent organic framework(COF)has distinctive properties that offer potential opportunities for developing advanced electrode *** this work,a core-shell material composed of TAPB-DMTP-COF(TAPB,1,3,5-tris(4-aminophenyl)benzene;DMTP,2,5-dimethoxyterephaldehyde)core and conducting polymer shell,TAPB-DMTP-COF@PANI,was synthesized solvothermally using a polymerization *** structural cha racteristics of the prepared composite were revealed by X-ray diffraction patterns(XRD),fourier transform infrared spectra(FTIR),X-ray photoelectron spectroscopy(XPS),transmission electron microscopy(TEM).The electrochemical analyses were verified by subsequent monitoring of trace levels of *** resultant composite not only facilitated acetaminophen to interact with absorption sites byπ-πstacking effect and hydrogen bonding but also overcame the poor conductivity of *** the optimal conditions,a low limit of detection of 0.032μmol/L and wide linear range of 0.10-500μmol/L were *** electrochemical platform was almost unaffected by other interfering substances,and successfully applied for the practical detection of acetaminophen in commercial tablet,human blood serum and *** enhanced performance makes this COF based core-shell composite a promising material in electrochemical senso r.

摘要：[目的/意义]以2018年前期调查资料为参照,以2023年现状调研数据为根据,纵向回溯与横向对比国内外公共图书馆文创产品的变化异同与发展态势,洞察凝练新时代我国公共图书馆文创产品开发思路。[方法/过程]运用网络调研、实地考察和电话访谈法,通过浏览、分类、记录的方式从载体形态、文化元素和创意手法的角度解析国内外公共图书馆文创产品内涵特征。[结果/结论]国外公共图书馆文创产品在明星藏品打造、专题文创开发、产品创意设计、数字文创赋能方面呈现稳步发展、不断深化;国内公共图书馆文创产品在文创品牌建设、主题系列集聚、载体形态转变、数字藏品拓展方面展开创新探索、亮点突出;同时,国内外公共图书馆文创产品在品类、元素、设计、形式4个方面存在共通处与相异点。经综合分析,提出新时代我国公共图书馆文创产品开发思路:挖掘馆藏特色文化内涵,增设创意产品新品类;拓宽创意符号灵感来源,映射产品开发新光彩;活用多维创意设计手法,传达古今文化新意境;聚焦用户需求偏好分类,助推文创功用新融合;推动文化数字融合创新,再现传统文化新灵韵。

摘要：Numerical simulations and experiments showed that bump inlet had a remarkable effect on boundary layer diversion of supersonic ***,the design and analysis of bump in hypersonic flow was still *** this paper,the mechanism of a supersonic bump inlet is introduced to the design of hypersonic forebody.A hypersonic inlet with an integrated bump/forebody is obtained by the Method Of Characteristics(MOC)based on a chin *** simulations show that the modified inlet achieves diversion of low-speed ***,the integrated bump/-forebody is also beneficial to inlet *** the starting process,the shape of the separation zone is rebuilt by the modified forebody surface which makes spillage much *** new design leads to a reduction of the self-start Mach number by 0.95.

摘要：The conventional microwell-based platform for construction of organoid models exhibits limitations in precision oncology applications because of low-speed growth and high variability. Here, we established organoid models on a nested array chip for fast and reproducible drug testing using 50% matrigel. First, we constructed mouse small intestinal and colonic organoid models. Compared with the conventional microwell-based platform, the mouse organoids on the chip showed accelerated growth and improved reproducibility due to the nested design of the chip. The design of the chip provides miniaturized and uniform shaping of the matrigel that allows the organoid to grow in a concentrated and controlled manner. Next, a patient-derived organoid(PDO) model from colorectal cancer tissues was successfully generated and characterized on the chip. Finally, the PDO models on the chip, from three patients, were implemented for high-throughput drug screening using nine treatment regimens. The drug sensitivity testing on the PDO models showed good quality control with a coefficient of variation under 10% and a Z’ factor of more than 0.7. More importantly, the drug responses on the chip recapitulate the heterogeneous response of individual patients, as well as showing a potential correlation with clinical outcomes. Therefore,the organoid model coupled with the nested array chip platform provides a fast and reproducible means for predicting drug responses to accelerate precise oncology.

摘要：Transverse pressure gradient(TPG)is one of the key factors influencing the boundary layer airflow diversion in a bump *** paper proposes a novel TPG-based hypersonic bump inlet design *** method consists of two ***,a parametric optimization approach is employed to design a series of 2D inlets with various compression ***,according to the prescribed TPG,the optimized inlets are placed in different osculating planes to generate a 3D bump *** method provides a means to directly control the aerodynamic parameters of the bump rather than the geometric *** performing this method to a hypersonic chin inlet,a long and wide bump surface is formed in the compression wall,which leads to good integration of the bump/*** show that a part of the near-wall boundary layer flow is diverted by the bump,resulting in a slight decrease in the mass flow but a significant improvement in the total pressure *** addition,the starting ability is significantly improved by adding the bump *** reveals that the bump has a 3D rebuilding effect on the large-scale separation bubble of the unstarted ***,a mass flow correction is performed on the designed bump inlet to increase the mass flow to full airflow *** results show that the mass flow rate of the corrected bump inlet reaches up to 0.9993,demonstrating that the correction method is effective.

摘要：Hydrogen peroxide(H2O2)is a very useful chemical reagent,but the current industrial methods for its production suffer from serious energy consumption *** high-activity and high-selectivity catalysts to electrocatalyze the oxygen reduction reaction(ORR)through a two-electron(2e^-)pathway is a very promising route to produce *** this work,we obtained partially oxidized multi-walled carbon nanotubes(MWCNTs)with controlled structure and composition by oxidation with concentrated sulfate and potassium permanganate at 40℃ for 1 h(O-CNTs-40-1).The outer layers of O-CNTs-40-1 are damaged with defects and oxygen-containing functional groups,while the inner layers are maintained *** optimized structure and composition of the partially oxidized MWCNTs ensure that O-CNTs-40-1 possesses both a sufficient number of catalytic sites and good *** results of rotating ring disk electrode measurements reveal that,among all oxidized MWCNTs,O-CNTs-40-1 shows the greatest improvement in hydrogen peroxide selectivity(from ~ 30% to ~ 50%)and electron transfer number(from ~ 3.4 to ~ 3.0)compared to those of the raw *** results of electrochemical impedance spectroscopy measurements indicate that both the charge-transfer and intrinsic resistances of O-CNTs-40-1 are lower than those of the raw MWCNTs and of the other oxidized ***,direct tests of the H2O2 production confirm the greatly improved catalytic activity of O-CNTs-40-1 relative to that of the raw MWCNTs.

摘要：Micro-/nano-patterns on hydrogels are widely used in cell ***,manufacturing molds with traditional lithography is time-consuming and *** addition,the excessive demolding force can easily damage patterns since biocompatible hydrogels are ultra-soft or ***,we presented a novel method for rapid and mass fabrication of cell ***-precision three-dimensional(3D)printing was used to manufacture a mold with a resolution of 2µm,and the gelatin-based hydrogel was cured by thermal–photo-crosslinking so that the low-concentration and low-substitutionrate hydrogel could be demolded *** found that pre-cooling before illumination made gelatin-based hydrogels resilient due to the partial regain of triple-helix *** this method,arbitrarily customized hydrogel patterns with a feature size of 6–80µm can be fabricated stably and at low *** cardiomyocytes were seeded on ultra-soft hydrogels with parallel groove structures,a consistent and spontaneous beating with 216 beats per minute(BPM)could be observed,approaching the natural beating rate of rat hearts(300 BPM).Overall,this work provides a general scheme for manufacturing cell patterns which has great potential for cell ethology and tissue repair.

摘要：Selective hydrogenation of 1,3‐butadiene is an essential process in the upgrading of the crude C4 cut from the petroleum chemical *** design is crucial to achieve a virtually alkadiene‐free product while avoiding over‐hydrogenating valuable *** addition to the great industrial relevance,this demanding selectivity pattern renders 1,3‐butadiene hydrogenation a widely used model reaction to discriminate selective hydrogenation catalysts in ***,critical reviews on the catalyst development are extremely lacking in *** this review,we aim to provide the reader an in‐depth overview of different catalyst families,particularly the precious metal‐based monometallic catalysts(Pd,Pt,and Au),developed in the last half *** emphasis is placed on the development of new strategies to design high‐performance architectures,the establishment of structure‐performance relationships,and the reaction and deactivation *** directions for future optimization of catalyst formulations and engineering aspect are also provided.