摘要：介绍新能源自卸渣土车用12R22.5全钢载重子午线轮胎的设计。结构设计:外直径1 099 mm,断面宽298mm,行驶面宽度240mm,行驶面弧度高8mm,胎圈着合直径569.5mm,胎圈着合宽度230mm,胎面采用复合花纹设计,花纹深度20 mm,花纹饱和度61.86%,花纹周节数40。施工设计:胎面胶采用天然橡胶并用改性丁苯橡胶配方,1^(#)和2^(#)带束层采用3×0.20+6×0.35HT钢丝帘线,3^(#)带束层采用5×0.35HI钢丝帘线,0°带束层采用3×7×0.20HE钢丝帘线,胎体采用0.17+5×0.215+10×0.235CCST超高强度钢丝帘线,采用三鼓一次法成型机成型、热板式硫化机硫化。成品性能测试结果表明,轮胎的室内性能结果达到相应的设计和国家标准要求,道路测试结果达到设计目标。

摘要：为了进一步研究平钢板-UHPC组合桥面板在疲劳荷载下的受力性能,基于某大跨径组合梁斜拉桥的桥面板设计,进行了2块不同配筋率(1.69%、1.86%)足尺模型的超高周负弯矩疲劳荷载试验及其研究。疲劳试验中,研究了试件裂缝宽度、刚度、UHPC应变、受拉钢筋应变、钢板应变随循环加载次数的变化规律。试验结果表明:以裂缝宽度0.1 mm为寿命标准,在荷载比R为0.25、荷载水平S≥0.8的疲劳荷载作用下,平钢板-UHPC组合桥面板裂缝宽度随循环次数增长缓慢,其疲劳寿命不低于1600万次;平钢板-UHPC组合桥面板刚度随循环次数增加缓慢下降,抗负弯极限承载力几乎没有衰减;受拉钢筋对UHPC的约束作用抑制了裂缝沿深度方向的扩展,使得在UHPC表面至顶层纵向钢筋之间存在钢纤维可能疲劳拔断区域;当该区域深度有限时,其对钢-UHPC组合桥面板抗负弯疲劳性能及剩余承载力下降的影响可忽略不计。平钢板-UHPC组合桥面板的疲劳设计应是防止裂缝宽度过大引起锈蚀的耐久性控制。

摘要：We present a semi-custom design methodology based on transistor tuning to optimize the design performance. Compared with other transistor tuning approaches, our tuning process takes the cross-talk effect into account and prominently reduces the complexity for circuit simulation and analysis by decomposing the circuit network utilizing graph theory. Furthermore, the incremental placement and routing for the corresponding transistor tuning in conventional approaches is not required in our methodology, which might induce timing graph variation and additional iterations for design convergence. This methodology combines the flexible automated circuit tuning and physical design tools to provide more opportunities for design optimization throughout the design cycle.

摘要：In search of environmentally benign insecticides with high activity, low toxicity and low residue, a series of novel anthranilic diamide derivatives containing N-pyridylpyrazole was designed and synthesized. All the compounds were characterized by H NMR spectroscopy and elemental analysis. The single crystal structure of com pound 8j was determined by X-ray diffraction. The insecticidal activities of the new compounds were evaluated. The results show that some compounds exhibited moderate insecticidal activities against Lepidoptera pests. Among this series of compounds, compounds 80 and 8p showed 100% larvicidal activity against Mythimna separate Walker, Plutella xylostella linnaeus and Laphygma exigua Hubner at a test concentration of 200 mg/kg, which is equal to the commercial chlorantraniliprole.

摘要：介绍325/95R24全钢载重子午线轮胎的设计。结构设计:外直径1 222 mm,断面宽315 mm,行驶面宽度225 mm,行驶面弧度高7.5 mm,胎圈着合直径610 mm,胎圈着合宽度230 mm,断面水平轴位置(H_(1)/H_(2))1.124,胎面采用大块混合花纹设计,花纹深度15.5mm,花纹饱和度60.86%,花纹周节数71。施工设计:胎面采用大分层结构,1^(#)和2^(#)带束层采用3+9+15×0.22W钢丝帘线,3^(#)带束层采用5×0.30HI钢丝帘线,胎体采用0.25+6+12×0.225HT钢丝帘线,采用两鼓一次法成型机成型、热板式硫化机硫化。成品性能试验结果表明,轮胎的充气外缘尺寸、强度性能和耐久性能均达到相应的设计和国家标准要求。

摘要：大脑内的程序性细胞死亡(PCD)贯穿生命全过程,异常PCD可能是导致脑病的重要因素。本文围绕针刺对PCD的影响,从传统中医学角度总结了针刺产生脑保护作用的理论基础及多靶点、双向、整体调节等治疗特点;从现代医学角度对针刺调节细胞凋亡、自噬、焦亡、铁死亡、坏死性凋亡等方面进行了梳理,探讨针刺基于PCD恢复或重塑受损脑功能,改善脑病的作用机制。

摘要：Diamidine （A） was identified in our in vitro bio-assay as a possible inhibitor of ketol-acid reductoisomerase （KARI） from the ACD database search based on the known three-dimensional crystal structure of KARI. An investigation on interaction of A on KARI active sites, led to the design and synthesis of 15 novel monoamidines. Some of those showed better biological activity than A on rice KARI （in vitro） and in greenhouse herbicidal tests （in vivo）. The structure-biological activity relationship was investigated, which provides valuable information to further study of potential KARI inhibitors.

摘要：Thirteen new ethyl 2-（N-substituted-arylsulfonamido）-2-oxoacetates（3a-3m）, based on the structure of Ketol-acid reductoisomerase（KARI） inhibitor IpOHA, were designed and synthesized. Their structures were established on the basis of ^1H NMR, IR, MS, and elemental analyses. The bioassay result reveals that the structural changes from hydroxyl group on the N atom of IpOHA to arylsulfonyl groups does not enhance the inhibitory activity of the compounds to KARI in vitro. Compounds 3c, 3h, 3k, and 3m are more effective than IpOHA against the monocotyledonous bamygrass at 100 ug/mL in herbicidal tests.

摘要：In order to design the scale model in a wide frequency range,a method based on the reflective loss is proposed according to the high-frequency approximation algorithm,and an example of designing the scale model of a plate-shaped absorber is given in this *** the example,the frequency of the full-size measurement ranges from 2.0 GHz to 2.4 GHz,the thickness of the full-size absorber is 1 mm and the scale ratio is 1/5.A two-layer scale absorber is obtained by the proposed *** thickness values of the bottom and top layer are 0.4 mm and 0.5 mm,***,the scattering properties of a plate model and an SliCY model are studied by FEKO to verify the effectiveness of the designed scale *** with the corresponding values from the theoretical scale model,the average values of the absolute deviations in 10 GHz～12 GHz are 0.53 d Bm^2,0.65 d Bm^2,0.76 d Bm^2 for the plate model and 0.20 d Bm^2,0.95 d Bm^2,0.77 d Bm^2 for the SliCY model while the incident angles are 0°,30°,and 60°,*** deviations fall within the Radar cross section（RCS） measurement ***,the work in this paper has important theoretical and practical significance.

摘要：分析建设工程噪声监测数据异常特征,用4M1E方法深入分析导致噪声数据异常的原因,并用鱼刺图法列举噪声数据异常的影响因素。在此基础上,提出一系列提升建设工程噪声监测数据质量的对策。