摘要：In assessing an insect-resistant genetically engineered （IRGE） crop before its commercialization, researchers normally use so-called ＂Tier-1 assays＂ as the initial step to determine the effects of the crop on non-target organisms. In these tests, the insecticidal proteins （IPs） produced by the IRGEs are added to the diets of test organisms in the laboratory. Test organisms in such assays can be directly exposed to much higher concentrations of the test IPs than they would encounter in the field. The results of Tier-1 assays are thus more conservative than those generated in studies in which the organisms are exposed to the IPs by feeding on IRGE plant tissue or in the case of predators or parasites, by feeding on invertebrate prey or hosts that have fed on IRGE plant tissue. In this report, we consider three important factors that must be considered in Tier-1 assays： （i） methods for delivery of the IP to the test organisms; （ii） the need for and selection of compounds used as positive controls; and （iii） methods for monitoring the concentration, stability and bioactivity of the IP during the assay. We also analyze the existing data from Tier-1 assays regarding the toxicity of Bt Cry proteins to non-target arthropod species. The data indicate that the widely used Bt proteins have no direct toxicity to non-target organisms

摘要：利用计算机可快速生成风格奇特的分形图,这些图案可用于纺织品的设计与开发。为此研究利用JCAD软件将由计算机生成的分形图编辑转化为意匠图并输出纹板文件,再通过电子提花机读取文件进行纹织产品织造,实现了由分形图案向数码纹织产品的快速转换。

摘要：针对在汽车运输船货舱通风系统的设计过程中,错误解读相关规范和标准会导致大幅增加船舶的建造成本,影响整船的安全性的问题,对规范或标准SOLAS、Circ.1515、ISO 9785、MSC.337(91)进行分析,从换气次数,通风流场,快速关闭,货舱内负压和噪声控制5个方面进行讨论。分析结果表明,为了节能可以安装空气质量控制系统,为改进流场可以布置射流风机,采用气动风闸或带盖百叶窗,运用机械抽风的通风形式,内外部风口进行降噪等设计原则。研究成果可为汽车运输船货舱通风设计提供参考。

摘要：边坡抗滑设计一般采用的是传统强度折减法(如不平衡推力法等),其设计力的依据为不平衡推力等。在分析边坡沿滑面应力分布的基础上,提出了沿滑面3种不同抗滑措施的布置方法;通过对边坡稳定性抗滑设计的计算研究,提出了不同工况下抗滑力的取值方法;结合边坡多参量时空稳定性评价指标,创建了边坡抗滑设计中的分项系数设计方法,并定义了主滑方向和边坡破坏概念。将提出的边坡抗滑措施的布置和抗滑力的取值方法、分项系数设计方法应用于工程(如湖北省十堰市布袋营滑坡)实践,经过多年的运行表明:该抗滑设计的防治措施位置选取、抗滑力的决定及分项系数设计方法是可行的。

摘要：以产品开发为目标,根据高压共轨柴油机燃油喷射特点设计了失火发生器。失火发生器采用16位MC9S12XS128单片机和FPGA分别设计了失火发生器的主控模块和远程控制模块,同时采用模块化设计方法设计了各模块的控制程序。试验结果表明：控制系统能够按照设定的失火模式和失火率发生失火,最大脉冲数可达10次,最大缸数为8缸,失火率控制精度达±0.1%,可设置的失火范围为0-99.9%,适合四冲程多缸发动机。

摘要：Background:Renal artery stenosis (RAS) is always associated with abnormalities in renal microvascular perfusion (RMP).However,few imaging methods can simultaneously evaluate the degree of luminal stenosis and ***,this study will aim to evaluate the feasibility of using contrast-enhanced ultrasound (CEUS) for assessing both RAS and RMP to achieve a one-stop assessment of patients with suspected renovascular hypertension. Methods:This will be a single-center diagnostic study with a sample size of *** with chronic kidney disease (CKD) and suspected of having resistant hypertension will be *** with Stages 1–3 CKD will undergo CEUS and computed tomography (CT) angiography (CTA).Values obtained by CEUS and CTA for diagnosing low-grade (lumen reduced by <60%) and high-grade (lumen reduced by ≥60%) RAS will be ***,all patients will also undergo radionuclide *** diagnostic value for RAS will be assessed by the receiver operating characteristic curve,including the accuracy,sensitivity,specificity,positive predictive values,negative predictive values,and area under the *** correlation analysis will be performed to assess the association between CEUS findings for RMP and glomerular filtration rate measured by a radionuclide imaging method. Conclusion:The data gathered from this study will be used to evaluate the feasibility of expanding clinical applications of CEUS for evaluation of patients with suspected renovascular hypertension.

摘要：采用40nm CMOS工艺设计了一款在250MS/s采样率下具有1.8Vpp满摆幅和低谐波失真性能的流水线ADC(Analog-to-Digital Converter).针对传统源跟随器结构的输入缓冲器在大摆幅下驱动大采样电容时线性度恶化的问题,采用了改进型电流注入技术和漏端电压自举技术.ADC中实现采样和电荷转移功能的开关采用薄栅器件设计,其工作电压由片上LDO(Low Dropout Regulator)提供,在降低开关寄生和电荷注入的同时保障了器件的可靠性.测试结果表明,对于10.1MHz单音输入,该ADC在-1dBFS下的信噪失真比、无杂散动态范围和总谐波失真分别为68.3dB、76.4dBc、-75.1dBc,在-1.57dBFS下的信噪失真比、无杂散动态范围和总谐波失真分别达68.3dB、80.1dBc、-78.6dBc.

摘要：提出一种以性价比为评价指标,运用快速拉格朗日差分分析和遗传算法对斜坡加固方案进行优化的新方法。应用FLAC计算斜坡加固前后的稳定性系数(Ks),以性价比(加固前后稳定性系数的差和工程造价的比)为目标函数,以加固后的稳定性系数大于等于安全系数为约束条件,应用遗传算法在加固方案的解空间中搜索目标函数的最大值,与其对应的各加固设计参数为加固方案的全局最优解。利用Visual C++语言,定义一个基于二值数编码的遗传算法类,编制斜坡加固方案优化设计的主程序,实现FLAC3D与遗传算法的串接。应用该方法对交河故城土遗址建筑载体,即47号崖体锚杆加固方案的8个设计参数进行优化。遗传操作执行到第55代时,性价比收敛于最大值0.012 95,与之对应的锚固方案能将崖体的稳定性系数提高0.391,工程造价为30.2万元,较经典算法的计算结果节约成本37%。

摘要：针对车辆边缘计算系统中的计算资源管理问题,提出一种基于李雅普诺夫随机优化的计算卸载与资源分配方案.构建在保证任务量及长期能耗约束下的车辆用户服务时延最小化优化问题,利用李雅普诺夫随机优化理论将优化问题分解.在本地计算资源分配子问题中,通过求解线性问题的方法,得到最优本地计算CPU频率;在计算卸载子问题中,利用数值优化求解得到最优发射功率.借助李雅普诺夫随机优化中的漂移惩罚方法,设计一种低复杂度的联合计算卸载与资源分配算法,通过同时控制卸载决策、本地计算CPU频率和计算卸载的发射功率,实现整个车辆边缘计算系统中车辆用户的服务时延最小,提高车辆边缘计算服务质量.仿真结果验证了所提出算法的有效性.

摘要：介绍了ASI技术及设计方法 ,提出了基于ASI技术的CAD/CAPP集成框架 ,以及家具产品参数化设计、CAD/CAPP集成应用和产品BOM生成的方法。该方法在指导CAD集成系统的开发中具有一定的实用价值。应用该技术和方法成功地研制了黑龙江省应用工程项目“家具计算机辅助设计系统FCADS”。