摘要：The light spectrometer is one of the most widely used optical instruments,allowing users to measure and analyze spectral ***,to reach a broad spectral response range,most spectrometers have to combine a silicon photodiode with an additional photodiode to account for the limited operating wavelength range of each in ***,we developed organic photodiodes(OPDs)by combining a novel narrow-bandgap non-fullerene acceptor(COTIC-4 Cl)with a polymer donor(PCE10)in the presence of PC71 BM as the third *** resulting device based on the ternary blended material showed a wide spectral response from 300 to 1200 nm,beyond the response range of the traditional silicon-based ***,at the wavelength of 1100 nm,the resulting OPD exhibited a specific detectivity of 5×10^(12) Jones and a responsivity of 0.3 A W-1,with a cut-off frequency of>1 MHz and a linear dynamic range of>120 d B,among the best performances of *** particular importance is that,as a proof-of-concept,the resulting ternary OPD was successfully utilized as the key component of a spectrometer to measure the absorption across 300–1200 *** results indicate the potential applications of the broadband response OPDs for next-generation spectrometers.

摘要：Unc-51样自噬激活激酶1(ULK1)作为自噬启动的重要调控因子,是肿瘤治疗的关键靶点之一。首先,以已知ULK1抑制剂为基础构建药效团模型,通过药效团模型筛选、分子对接以及分子力学广义波恩表面积(MM/GBSA)结合自由能计算等方法,对含有52万多个类药性小分子的数据库进行虚拟筛选,得到具有较高理论亲和力的化合物。随后,50ns的分子动力学模拟验证了蛋白质-配体复合物结合的稳定性,最后10ns的平均结合自由能的计算研究进一步验证了配体的结合能力。结果表明,6个化合物(F5258-0159、F3407-0428、F0529-1100、F0696-3531、F3222-5280、F6525-5596)具有骨架新颖、分子对接分数和结合自由能数值优异及与ULK1的结合状态稳定等特点,可以作为新型潜在的ULK1抑制剂用于肿瘤治疗的研究,也为新型ULK1抑制剂的设计和研发提供新的研究思路。

摘要：针对新探区裂缝性地层地质及工程资料严重缺乏,导致现有漏失压力计算模型有效性降低这一问题,文中提供了一套地质工程一体化裂缝性地层漏失压力预测方法,即在现有漏失压力计算模型的基础上,引入裂缝指数,结合钻井液漏失机理,制定漏失类型分类评价指标,形成裂缝性地层漏失压力三维建模方法。另外,建立了渤海A油田漏失层漏失类型分类评价指标,对A油田进行了三维漏失压力建模及预测,并在C-5井成功应用,钻井周期缩短15 d。应用结果表明,A油田的裂缝指数与漏点位置相关。文中方法综合利用地质、工程、地质力学数据,可为新探区提供可靠的漏失压力精细预测结果,有助于新探区的钻井优化设计和管理。

摘要：针对高原矿井机械化掘进巷道传统扩散式增氧通风方案富氧效率较低及氧气资源浪费严重等问题,提出了一种新型分段式增氧通风方案。基于ANSYS-Fluent数值模拟软件,针对某海拔4000 m的金属矿山掘进巷道,以掘进巷道需氧区域氧浓度提升至26%为目标,设计对比试验,分析传统扩散式增氧通风方案与分段式增氧通风方案掘进巷道的富氧扩散、氧气空间分布差异,并引入目标富氧偏离量和富氧输运效率2项指标,评估分段式增氧通风与传统扩散式增氧通风的富氧能力。结果表明:与传统扩散式增氧通风相比,分段式增氧通风的富氧扩散速率得到明显提升,增氧范围扩大,富氧耗时显著降低,巷道中段、末段需氧区域氧浓度分别上升至24.6%和25.5%,目标富氧偏移量降低至1.372,氧气利用率上升至50%,充分验证了分段式增氧通风方案富氧的有效性和优越性。该研究成果对于高原矿井制定机械化掘进巷道通风方式具有一定的指导意义。

摘要：温度的检测与控制一直是工业控制中常用的技术手段,在工业智能化要求下,在某些特殊设备中不仅需要远程监控整体温度同时也需要监控局部多点温度。本系统采用温度采集芯片MAX6675与多路K型热电偶相结合作为采集模块,以单片机MSP430F149为核心,通讯模块采用以太网通讯智能模块IPort-2,设计一套温度采集系统,经验证,该方法抗干扰性强,易于大规模组网适用于对温度控制要求较高的场合。

摘要：Proton exchange membrane(PEM)fuel cell has been regarded as a promising approach to the decarbonization and diversification of energy *** recent years,durability and cost issues of PEM fuel cells are increasingly significant with the rapid increase of power ***,the failure to maintain the cell consistency,as one major cause of the above issue,has attracted little ***,this study intends to figure out the underlying cause of cell inconsistency and provide solutions to it from the perspective of multi-physics transport coupled with electrochemical *** PEM fuel cells with electrodes under two compression modes are firstly discussed to fully explain the relationship of cell performance and consistency to electrode structure and multi-physics *** result indicates that one main cause of cell inconsistency is the intrinsic conflict between the separated transport and cooperated consumption of oxygen and electron throughout the active ***,a mixed-pathway electrode design is proposed to reduce the cell inconsistency by enhancing the mixed transport of oxygen and electron in the *** is found that the mixing of pathways in electrodes at under-rib region is more effective than that at the under-channel region,and can achieve an up to 40%reduction of the cell inconsistency with little(3.3%)sacrificed *** addition,all the investigations are implemented based on a self-developed digitalization platform that reconstructs the complex physical–chemical system of PEM fuel *** fully observable physical information of the digitalized cells provides strong support to the related analysis.

摘要：简述目前火电厂中除氧器水箱焊缝裂纹的特点，分析裂纹产生原因，并提出在结构设计、安装制造及运行管理中应注意的问题和应采取的防止措施。

摘要：不同于传统车辆行为识别方法大多基于鸟瞰视角下的历史轨迹信息,该文提出了一种用于自动驾驶汽车的车载视角下基于视觉信息的前车行为识别方法。针对缺乏车辆行为数据集的问题,提出了基于车载视频信息的车辆行为标注方法,构建了车载视角下的行为识别数据集。设计了一种基于SlowFast网络为主体的车辆行为识别算法,设计了焦点损失函数,并引入非局部操作模块来替换原有的交叉熵损失函数。结果表明:相较于原SlowFast模型,新模型的总体准确率提高了20.56%,实现了对视频中前方多台车辆的行为识别。

摘要：深水高温高压气井钻井过程中,井筒大温差、大压差效应会使钻井液性能发生较大改变,进而影响井筒流动参数和钻井施工安全,因此准确模拟井筒温压场对确保深水高温高压井安全钻进至关重要。根据深水钻井工艺和高温高压地层的特点,充分考虑了井筒温压场和钻井液性能相互影响,结合增压管线流体进入隔水管环空引起的传热和传质,建立了适用于深水高温高压气井钻井的井筒瞬态温度压力耦合计算模型,提出了相应的迭代求解算法,并通过实例计算,进行了参数敏感性分析。研究结果表明:本文模型计算值与现场实测数据基本吻合,验证了模型的正确性;隔水管增压管线排量会使环空温度显著降低,进而影响整个井筒温度,因此不可忽略增压排量的影响;钻井液性能受井筒温度和压力影响较明显,在计算过程中忽略温度,压力和钻井液性能之间的耦合作用会产生较大误差。本文研究成果可为深水高温高压气井钻井过程中井筒温压场预测及水力参数设计提供理论指导。

摘要：国内外高端航测相机不断追求扩展摄影幅面以提升作业效率,但探测器制造能力对相机单一幅面扩展形成了制约,多镜头、多探测器拼接技术成为大幅面高端航测相机的重要发展路线。文章针对拼接式航测相机虚拟拼接影像各子影像亮度不一致的问题,提出一种无需输入先验参数,自主选择参考子影像,使用子影像间设计重叠区域亮度统计特征(均值、标准差)一致性约束,构建线性校正模型,通过最小二乘优化求解各个子影像的校正参数。文章方法针对虚拟拼接影像,可以无先验、自适应地计算最优校正参数,有效抑制拼接式相机多镜头、多探测器间辐射不一致的现象,提升影像品质。经试验验证,提出方法与现有算法相比,校正后的虚拟拼接影像的均匀性在定量分析与视觉效果两方面均有显著提升。