摘要：Dermal substitutes have provided a template for the regeneration and reconstruction of the ***,the healed skin tissue often exhibits abnormal morphology and functionality,including scarring and *** this study,a composite bioink composed of methacrylated gelatin(GelMA)and chitosan oligosaccharide(COS)was proposed for printing a dermal scaffold using digital light processing(DLP)*** GelMA/COS bioink exhibited suitable porosity,swelling,degradation rate,and mechanical *** inclusion of COS demonstrated antibacterial effects against both Gram positive and Gram-negative bacteria,while simultaneously fostering the proliferation of human dermal fibroblasts(HDFs).Additionally,the application of COS could effectively reduce the expression levels of fibrosis-related genes,such as collagen I,collagen III,and fibronectin *** three-dimensionally printed cell-laden dermal scaffold exhibited excellent shape fidelity and high cellular viability,facilitating the extension of HDFs along the scaffold and the simultaneous secretion of extracellular matrix ***,the HDF-laden dermal scaffold transplanted into full-thickness skin defect sites in nude mice was shown to accelerate wound closure,reduce inflammation,and improve wound ***,the DLP-printed dermal scaffold provides an appealing approach for effectively treating full-thickness skin defects in clinical settings.

摘要：Traditional tumor models do not tend to accurately simulate tumor growth in vitro or enable personalized treatment and are particularly unable to discover more beneficial targeted *** address this,this study describes the use of threedimensional(3D)bioprinting technology to construct a 3D model with human hepatocarcinoma SMMC-7721 cells(3DP-7721)by combining gelatin methacrylate(GelMA)and poly(ethylene oxide)(PEO)as two immiscible aqueous phases to form a bioink and innovatively applying fluorescent carbon quantum dots for long-term tracking of *** GelMA(10%,mass fraction)and PEO(1.6%,mass fraction)hydrogel with 3:1 volume ratio offered distinct pore-forming characteristics,satisfactorymechanical properties,and biocompatibility for the creation of the 3DP-7721 *** analysis and quantitative real-time fluorescence polymerase chain reaction(PCR)were used to evaluate the biological properties of the *** with the two-dimensional culture cell model(2D-7721)and the 3D mixed culture cell model(3DM-7721),3DP-7721 significantly improved the proliferation of cells and expression of tumor-related proteins and ***,we evaluated the differences between the three culture models and the effectiveness of antitumor drugs in the three models and discovered that the efficacy of antitumor drugs varied because of significant differences in resistance proteins and genes between the three *** addition,the comparison of tumor formation in the three models found that the cells cultured by the 3DP-7721 model had strong tumorigenicity in nude *** evaluation of the levels of biochemical indicators related to the formation of solid tumors showed that the 3DP-7721 model group exhibited pathological characteristics of malignant tumors,the generated solid tumors were similar to actual tumors,and the deterioration was *** research therefore acts as a foundation for the application of 3DP-7721 models in drug devel

摘要：研究了仿生机器鱼的自主避障控制，提出了一种集成超声和红外传感器的仿生机器鱼系统设计方案，为机器鱼安装了3个超声传感器和3个红外传感器。针对此仿生机器鱼系统，提出了一种基于增强式学习的仿生机器鱼自主避障控制策略，给出了状态集和行为集，采用当场奖励和延时奖励相结合的方法，通过学习获得了有效的状态行为组合。仿真实验验证了学习结果的有效性。

摘要：【目的】总结"家庭医生"微信公众号运营成功的经验,为其他医学科普期刊微信公众号的运营提供参考。【方法】采用个案研究法,通过定量和定性方法分析"家庭医生"微信公众号的文章推送、菜单设置、用户互动、传播方式等方面,总结其成功之道。【结果】"家庭医生"公众号推文的可读性强、公众号主页设置合理、采用跨媒体方式合作传播信息、开通多种盈利渠道是其影响力领先的主要因素。【结论】医学科普期刊公众号应构建联盟矩阵、重视服务用户、优化文章页面设计、丰富主页设置、建构多样化的盈利模式,从而增强医学科普效果。

摘要：3D打印技术已经在生物医学、传感器制造等领域得到广泛应用。然而,传统3D打印机由于自身工作方式的不同,适用范围不同,难以同时兼容生物制备和传感器制备。因此,以电磁阀作为3D打印机的喷头,自主设计并构建具有独特工作方式的3D打印机,将高精度液滴分配方式应用于3D结构打印。研究料筒气压、电磁阀开关时间、喷头高度对打印液滴直径的影响,并对点、线、网、面图案的打印质量进行评估;利用所构建的打印机制备具有真皮乳头结构的组织工程皮肤和阵列式柔性压力传感器,测试组织工程皮肤的细胞活性及压力传感器的压-阻转换特性。结果表明,打印液滴直径尺寸与料筒气压、喷头开启时间、喷头高度均成正相关;3D打印机对点、线、网、面图案的打印效果较为理想;可成功应用于具有真皮乳头结构的组织工程皮肤和柔性压力传感器的制备。所构建的3D打印机融合喷墨式打印机和挤出式打印机的优势,对打印墨水有较好的兼容性,具有打印方式简单、打印速度快、成型质量高的优点,对组织工程皮肤及柔性压力传感器的研究具有重要意义,为实现具有感知功能仿生皮肤的制备奠定基础。

摘要：地形数据是低空突防系统最主要的信息来源之一。由于机载条件对电子设备的重量和体积有很大的限制 ,因此地形数据必须要按低空突防的要求进行压缩以减小其存储空间。本文探讨并比较了采用 L PC,DCT和 BTC三种压缩算法进行低空突防用地形数据压缩的特点。文中首先设计了一个三阶预测器对地形数据进行 L PC压缩 ;其次给出了 DCT编码的恢复误差的估计式 ,并根据该估计式按低空突防要求选取量化矩阵以压缩地形数据 ;最后提出了一种块间自适应的 BTC算法。仿真结果表明 ,块间自适应 BTC算法的综合压缩性能较合乎低空突防的要求。

摘要：随着视频监控规模的不断增大,对视频监控终端进行自动诊断成为迫切需求。针对视频监控中经常发生的视频丢失故障,提出一种诊断算法,并进行系统设计和实现。该算法基于监控图像和差分图像的直方图分布特征,对视频丢失进行快速、准确的检测。通过对视频质量诊断系统实际运行结果进行分析,该算法能够满足视频监控故障自动诊断的需求。

摘要：农业博物馆是保护和传承农业历史文化遗产的重要方式。中华农业文明博物馆是国内高校建立的第一所系统展示中华农业文明和历史渊源的大型专题博物馆,在农业文化遗产保护与传承方面发挥着重要作用。本文结合国内外高校博物馆的传播现状,利用新媒体技术从应用层面建构中华农业文明博物馆的互动智慧传播模式,以期对中华农业文明博物馆在农业文化遗产传播与国际交流层面提供借鉴与参考。

摘要：为解决集磁环式光学电流互感器存在的线性度和准确度差的问题,提出了一种集磁环式光学电流互感器的自校正测量方法。该方法在常规集磁环式光学电流互感器的基础上增加基准电流源、自校正线圈和远端采集单元,并采用自校正算法进行数据处理,使常规的集磁环式光学电流互感器成为一个完整的自校正测量系统。实验结果表明,所设计的集磁环式光学电流互感器测量准确度等级满足IEC 0.2级的测量要求,可以有效提高集磁环式光学电流互感器的线性度和准确度,证明了自校正测量方法的正确性与实用性。同时为集磁环式光学电流互感器的实用化设计提供了新的思路。

摘要：光学电压传感器的测量精确度易受环境温度的影响。通过设计基准电压源,使基准电压源与被测电压源串联共同作用于同一个光学电压传感器,提出一种获取自校准系数的自校准算法,通过自校准系数对光学电压传感器测量结果进行修正,实现对光学电压传感器的温度补偿。基于该方法设计了自校准光学电压传感器,并对其进行了精确度测试。测试结果表明:在?40℃^+70℃的温度范围内,自校准光学电压传感器的测量误差小于±0.12%,其温度稳定性得到了显著提高。该方法简单有效,为实现实用化的高精确度光学电压互感器提供了解决方案。