摘要：The process of wound healing is routinely evaluated by histological evaluation in the clinic,which may cause scarring and secondary *** confocal microscopy(RCM)represents a noninvasive,real-time imaging technique that allows in vivo evaluation of the *** RCM was wide-probe-based,which limited its application on uneven and covered *** this study,we report the development of a portable reflectance confocal microscope(PRCM)in which all components were assembled in a handheld *** the size and weight of the PRCM were reduced based on the use of a microelectromechanical system,the resolution was kept at 0.91μm,and the field of view of the system was 343μm×532μ*** used in vivo,the PRCM was able to visualize cellular and nuclear morphology for both mouse and human *** evaluations were then performed on wounds after topically applied mesenchymal stem cells(MSCs)or saline *** PRCM allowed visualization of the formation of collagen bundles,re-epithelization from the wound edge to the wound bed,and hair follicle regeneration,which were consistent with histological ***,we offer new insights into monitoring the effects of topically applied MSCs on the process of wound healing by using *** study illustrates that the newly developed PRCM represents a promising device for real-time,noninvasive monitoring of the dynamic process of wound healing,which demonstrates its potential to diagnose,monitor,or predict disease in clinical wound therapy.

摘要：Large cutaneous wounds pose a severe medical problem and may be deadly in cases when regeneration is ***,topical stem cell therapy has been realized as a promising strategy for wound healing and skin ***,stem cells must be administrated uniformly to the wound area,otherwise treatment will be ineffective,which has been a limitation of current administration ***,the delivery pressure and nozzle features of most clinical cell spray devices are unknown,which may significantly affect the viability of sprayed cells and their capacity for ***,we developed a novel pneumatically assisted atomization device(PAAD)in which cell suspensions were uniformly atomized at a low delivery *** optimized the applied fluidic pressure and air pressure to maximize cell survival and function for the application of multiple cell types,while ensuring uniform dispersal across the wound ***,we found that the application of sprayed umbilical cord-derived mesenchymal stem cells to wound sites significantly accelerated wound healing and promoted appendage regeneration on an excisional cutaneous wound ***,the novel PAAD system delivered living cells uniformly and maintained the viability and differentiation of sprayed cells,strongly suggesting its potential for application in clinical cell therapy,especially for large,irregular,and severe skin wounds.

摘要：《状态监测与故障诊断》是一门注重基础理论知识和现场工业实践相结合的课程,通过对我校《状态监测与故障诊断》课程实验教学现状的总结和分析,指出存在的问题,探索改进实验教学的方法,优化实验方案、创新实验教学模式、拓展学生学习思路,提高学生的学习主动性,将课堂上传授的理论知识和实验教学更好地联系起来,提升学生的综合实践能力和工程素质,提高教学效果,为解决课程实验教学实用性不足和单一化教学提供了参考。

摘要：综述近年来在非轮胎橡胶制品领域拓展应用的一些具有特殊性能和特种用途、能在苛刻条件下使用的高性能特种弹性体。本综述第1部分包含新型三元乙丙橡胶(EPDM)——5-乙烯基-2-降冰片烯型EPDM、超高相对分子质量EPDM、超低门尼粘度EPDM、生物基EPDM和EPDM合金以及丙烯基弹性体和乙丁橡胶,介绍这些弹性体的品种、牌号和特性,列举其在汽车部件、胶管、胶带和密封件等橡胶制品中应用的胶料配方以及分析其胶料性能。

摘要：在合宁线试验段上进行了模拟列车荷载的动态激振试验,通过模拟降雨与不降雨两种试验条件,测试了路堑基床部分动应力、弹性变形、塑性变形等指标,并结合扫频试验,得出路基的综合动刚度、固有频率、竖向阻尼比等参数,为客运专线路基设计提供试验参数。

摘要：综述近年来在非轮胎橡胶制品领域拓展应用的一些具有特殊性能和特种用途、能在苛刻条件下使用的高性能特种弹性体。本综述第2部分介绍氢化丁腈橡胶在使用新型制冷剂的汽车空调密封件及长寿命汽车传动带中的应用;介绍新型的丙烯酸弹性体,包括耐高温丙烯酸酯橡胶、典型和高性能乙烯-丙烯酸酯橡胶及乙烯-乙酸乙烯-丙烯酸酯弹性体的结构、组成和特性;介绍3种新开发的乙烯-乙酸乙烯弹性体(EVM)——预交联EVM、环氧化EVM、耐寒EVM。

摘要：综述近年来在非轮胎橡胶制品领域拓展应用的具有特殊性能和特种用途、能在苛刻条件下使用的高性能特种弹性体。本综述第5部分介绍在高压-高温油气田系统发生爆炸减压或称快速气体减压现象造成橡胶部件(如密封件)起泡和爆裂损坏的成因以及用作抗爆炸减压弹性体的胶种和类型。抗爆炸减压弹性体必须通过有关国际公认的标准检测和认证并获得合格证书才能给油气工业用户供货。列出主要的认证检测标准,包括挪威标准NORSOK M-710、美国标准NACE TM 0297、法国标准TOTAL GS EP PW 142、国际标准ISO 23936-2,其中NORSOK M-710采用最为广泛。列举了一些高性能抗爆炸减压弹性体的胶料配方和性能。

摘要：综述近年来在非轮胎橡胶制品领域拓展应用的具有特殊性能和特种用途、能在苛刻条件下使用的高性能特种弹性体。本综述第4部分介绍氟橡胶的发展历程和分类,详述在通用氟橡胶(1型和2型氟橡胶)基础上拓展的高性能氟橡胶的组成和特性。这些高性能氟橡胶包括高氟含量氟橡胶、过氧化物硫化氟橡胶、耐低温氟醚橡胶(3型氟橡胶)[全氟甲基乙烯基醚(PMVE)基氟醚橡胶和全氟甲氧基甲基乙烯基醚(MOVE)基氟醚橡胶]、耐极端环境全氟醚橡胶、耐碱氟橡胶[四氟乙烯/丙烯二元共聚氟橡胶(四丙氟橡胶)、四氟乙烯/乙烯/PMVE和四氟乙烯/丙烯/偏氟乙烯三元共聚氟橡胶(4型氟橡胶)、四氟乙烯/六氟丙烯/偏氟乙烯/乙烯/PMVE五元共聚氟橡胶(5型氟橡胶)、四氟乙烯/四氟丙烯二元共聚氟橡胶(6型氟橡胶)]。本文报道在高性能氟橡胶领域国内外的研发信息,重点介绍高性能氟橡胶在我国获得的新进展。

摘要：综述近年来在非轮胎橡胶制品领域拓展应用的一些具有特殊性能和特种用途、能在苛刻条件下使用的高性能特种弹性体。本综述第3部分报道近年来高性能硅橡胶领域的一些研究和应用进展。添加新型热稳定剂(气相法二氧化钛)和耐热增效剂(3价金属-有机硅络合物)可以显著提高硅橡胶的耐高温性能。低苯基硅橡胶是比目前通用的甲基乙烯基硅橡胶耐高低温性能更优异的硅橡胶,可在-70~250℃热空气环境中长期使用,也可在300℃下短期使用。采用集中交联技术可获得高撕裂强度甲基乙烯基硅橡胶。概述陶瓷化硅橡胶的组成和陶瓷化过程,简述国内在瓷化体系(成瓷填料和助溶剂)以及阻燃陶瓷化硅橡胶方面的研究状况。介绍加成型液体硅橡胶的基本组成、功能性添加剂和交联反应原理及其在输配电用复合绝缘子中的应用。

摘要：民用飞机舱门的完全互换可以有效降低生产成本和运营成本,国外先进机型已经可以实现大型舱门的完全互换,我国民机舱门制造还普遍采用修切蒙皮的方式,尚未实现完全互换。为了提高民机产品竞争力,实现舱门的完全互换势在必行。分析了民用飞机完全互换舱门设计技术难点,给出了一种完全互换舱门设计技术解决方案,包括实施过程流程图、实施方法分解说明等。详细阐述了以六自由度姿态调整为主的舱门安装调整技术,以累积容差计算为主的舱门容差管理技术,基于舱门的安装调整结果、容差管理结果、刚度匹配结果的关键零组件设计补偿技术等完全互换舱门关键技术,为民用飞机完全互换舱门设计提供了参考,可以推广应用于民用飞机半堵塞式等形式的舱门设计中。