摘要：多伦多夏日的午后清爽而悠长，经历漫长冬日的人们尽情地拥抱灿烂的阳光。牛仔迷你裙、清雅印花短裙、开襟羊毛衫或是颜色鲜亮的运动裙活泼娇俏，尽显青春气息。带有破洞的黑色丝袜、牛仔服和迷彩裤．以及不经意间露出的颇有摇滚风情的纹身，玩的就是心跳!卡通图案或是后现代风格的印花T恤，搭配西装马甲与小圆礼帽，让都市雅皮的意味在街头肆意流淌。

摘要：Broad-host-range synthetic biology is an emerging frontier that aims to expand our current engineerable domain of microbial hosts for biodesign *** more novel species are brought to“model status,”synthetic biologists are discovering that identically engineered genetic circuits can exhibit different performances depending on the organism it operates within,an observation referred to as the“chassis effect.”It remains a major challenge to uncover which genome-encoded and biological determinants will underpin chassis effects that govern the performance of engineered genetic *** this study,we compared model and novel bacterial hosts to ask whether phylogenomic relatedness or similarity in host physiology is a better predictor of genetic circuit *** was accomplished using a comparative framework based on multivariate statistical approaches to systematically demonstrate the chassis effect and characterize the performance dynamics of a genetic inverter circuit operating within 6 *** results solidify the notion that genetic devices are strongly impacted by the host ***,we formally determined that hosts exhibiting more similar metrics of growth and molecular physiology also exhibit more similar performance of the genetic inverter,indicating that specific bacterial physiology underpins measurable chassis *** result of this study contributes to the field of broad-host-range synthetic biology by lending increased predictive power to the implementation of genetic devices in less-established microbial hosts.

摘要：巴拉曼大学始建于1988年，正值黎巴嫩内战即将结束之时。它紧邻一座已有800年历史的东正教修道院。诞生于战争岁月的巴拉曼大学肩负着一项重要的历史使命——促成中东地区基督教信徒与穆斯林之间的对话。学校新的院系也是根据需求临时设立的，并没有个完整的远景规划。

摘要：欧林事务所在设计中关注地方语境,本文介绍了其在弗吉尼亚大学艺术博物馆的景观设计。弗吉尼亚曾经是一片森林,早春时节树下生长着茂盛的草本植物。一年中大部分时间气候宜人,只有夏季炎热。托马斯·杰斐逊认为,在这里遮荫是必要的,并主张栽种树木以遮阳。欧林事务所的园林设计受其启发,种植了当地的郁金香树以遮蔽骄阳,并模仿森林中花草在树下绽放的景观,在郁金香树下种有常青草本植物。此外,草本植物栽种布局再现了弗吉尼亚古老园林的几何构图。

摘要：处理一张经典的图片可不是什么创意。而且尽管有利可图，它还是违法的。那些嫌疑犯们又能够逃过法网多久呢？

摘要：本文试图关注当前存在的一种两难局面：如何处理过去的存在,如何认知它并且由它开始创造,既不切断过去,也不压制对未来的设计。

摘要：Bone is known to have a natural function to heal ***,if the bone damage is beyond a critical degree,intervention such as bone grafting may be *** this work,the fabrication of a novel bone scaffold composed of natural bone components and polycaprolactone(PCL)using 3D printing is put forward.α1,3-galactosyltransferase deficient pigs were used as the donor source of a *** porcine bone(DCB)with attenuated immunogenicity was used as the natural component of the scaffold with the aim to promote bone *** 3D printed DCB-PCL scaffolds combined essential advantages such as uniformity of the interconnected macropores and high porosity and enhanced compressive *** biological properties of the DCB-PCL scaffolds were evaluated by studying cell adhesion,viability,alkaline phosphatase activity and osteogenic gene expression of human bone marrow-derived mesenchymal stem *** in vitro results demonstrated that the DCB-PCL scaffolds exhibit an enhanced performance in promoting bone differentiation,which is correlated to the DCB ***,critical-sized cranial rat defects were used to assess the effect of DCB-PCL scaffolds on bone regeneration in *** results confirm that in comparison with PCL scaffolds,the DCB-PCL scaffolds can significantly improve new bone formation in cranial ***,the proposed 3D printed DCB-PCL scaffolds emerge as a promising regeneration alternative in the clinical treatment of large bone defects.

摘要：驾驶员腰部的肌肉力、关节力等负载与驾驶舒适性密切相关,但难以直接测量。本文中建立了驾驶员肌肉骨骼生物力学模型,提出了一种基于Matlab-OpenSim联合仿真的驾驶员与座椅界面接触力和摩擦力计算求解方法,并通过人椅接触压力测试和接触界面摩擦力与腰椎关节压力仿真对上述模型和方法进行验证。结果表明,本文中提出的驾驶员肌肉骨骼生物力学模型和人椅界面接触负载的计算方法可有效解决行驶工况下驾驶员腰部负载的定量评估问题,对驾驶室空间布局和舒适性设计具有重要工程应用价值。

摘要：Rap Videos为人所知的地方不在于他们的前沿创意，反而常常依赖于那些扭腰摆臀的美女们。但Shimm1和Notion Studio这次并没有制作典型的Rap视频。

摘要：为提高驾驶人的乘坐舒适性,本文中对汽车座椅腰靠进行研究。基于驾驶人肌肉骨骼生物力学模型,对坐姿驾驶人在第三腰椎部位处3种不同凸出量(0,2和4cm)的腰靠支撑条件下,仿真求解了腰部椎间关节力和肌肉负载。结果表明,4cm凸出量的腰靠支撑下,驾驶人腰部的椎间关节力平均下降8%、肌肉负载平均下降15%,而2cm凸出量的腰靠支撑却使腰部椎间关节力和肌肉负载均略有升高。本文从腰部载荷的角度解释了腰靠凸出量对改善乘坐舒适性影响的内在机理,所提出的仿真方法可实现不同腰靠支撑下腰部载荷的定量评估,为座椅腰靠的舒适性设计提供指导。