摘要：提出了一种实时的图像素描风格化算法.根据素描以及人眼视觉的特点,利用人眼对颜色差异的敏感程度来勾勒图像的轮廓,并依据图像光感强度产生的重要性图来控制渲染素描风格画的阴影纹理,使得生成的素描风格画具有良好的艺术效果.与已有方法相比,该文算法不需要人工交互,生成的素描视觉效果更好,在速度上能达到实时.

摘要：变构调节(allosteric regulation)是生物体内普遍存在的一种调控方式,是指小分子结合在空间上不同于活性位点的变构位点(allosteric site)扰动周围的残基并将信号传导至活性位点从而改变蛋白功能的现象。2009 年以来,上海交通大学医学院张健研究组开发了一系列变构药物设计方法,并将其应用于多个药物靶点,已获得多个原创性的候选药物。上述系列研究成果以“Allosteric methods and their applications:facilitating the discovery of allosteric drugs and theinvestigation of allosteric mechanisms”为题于2019 年1 月在线发表于国际著名学术期刊Acc Chem Res,详细阐述了过去10 年该研究组在变构机制和药物设计领域的工作。

摘要：针对目前多目重构研究中物体表面获取和凹陷区域恢复的难题,提出采用窄带图切割的可见外壳和多目立体匹配相融合的方法.在可见外壳的拓扑约束下,通过最小化能量泛函使得重构表面与多目立体匹配得到的稠密点云形状一致;并利用窄带图切割计算能量泛函的全局最优解.实验结果表明,该方法能重构封闭表面和凹陷区域;窄带图切割在获得最优解的同时提高了计算效率,与全图切割相比速度提高了3倍以上.

摘要：Bone is known to have a natural function to heal ***,if the bone damage is beyond a critical degree,intervention such as bone grafting may be *** this work,the fabrication of a novel bone scaffold composed of natural bone components and polycaprolactone(PCL)using 3D printing is put forward.α1,3-galactosyltransferase deficient pigs were used as the donor source of a *** porcine bone(DCB)with attenuated immunogenicity was used as the natural component of the scaffold with the aim to promote bone *** 3D printed DCB-PCL scaffolds combined essential advantages such as uniformity of the interconnected macropores and high porosity and enhanced compressive *** biological properties of the DCB-PCL scaffolds were evaluated by studying cell adhesion,viability,alkaline phosphatase activity and osteogenic gene expression of human bone marrow-derived mesenchymal stem *** in vitro results demonstrated that the DCB-PCL scaffolds exhibit an enhanced performance in promoting bone differentiation,which is correlated to the DCB ***,critical-sized cranial rat defects were used to assess the effect of DCB-PCL scaffolds on bone regeneration in *** results confirm that in comparison with PCL scaffolds,the DCB-PCL scaffolds can significantly improve new bone formation in cranial ***,the proposed 3D printed DCB-PCL scaffolds emerge as a promising regeneration alternative in the clinical treatment of large bone defects.

摘要：为了取代传统的功能单一、电路复杂的固定功能的几何单元电路,设计了一个高性能的面向移动设备的可编程顶点处理器(VPU).该处理器采用了定点的4路单指令多数据(SIMD)的运算结构和具备数据旁路功能的流水线结构,并具有一个高精度的特殊函数求值单元.这些结构加快了处理器的运算速度,并有效减少了电路面积.该处理器已经在FPGA平台上实现.实验结果表明,该处理器能够完成几何部分的计算功能,并且允许用户编程实现自定义的变换模型和光照模型,以实现各种特殊效果.

摘要：Surface reconstruction from unorganized data points is a challenging problem in Computer Aided Design and Geometric Modeling. In this paper, we extend the mathematical model proposed by Juttler and Felis （Adv. Comput. Math., 17 （2002）, pp. 135-152） based on tensor product algebraic spline surfaces from fixed meshes to adaptive meshes. We start with a tensor product algebraic B-spline surface defined on an initial mesh to fit the given data based on an optimization approach. By measuring the fitting errors over each cell of the mesh, we recursively insert new knots in cells over which the errors are larger than some given threshold, and construct a new algebraic spline surface to better fit the given data locally. The algorithm terminates when the error over each cell is less than the threshold. We provide some examples to demonstrate our algorithm and compare it with Juttler＇s method. Examples suggest that our method is effective and is able to produce reconstruction surfaces of high quality.

摘要：This paper focuses on solving a problem of improving system robustness and the efficiency of a distributed system at the same time. Fault tolerance with active replication and load balancing techniques are used. The pros and cons of both techniques are analyzed, and a novel load balancing framework for fault tolerant systems with active replication is presented. Hierarchical architecture is described in detail. The framework can dynamically adjust fault tolerant groups and their memberships with respect to system loads. Three potential task scheduler group selection methods are proposed and simulation tests are made. Further analysis of test data is done and helpful observations for system design are also pointed out, including effects of task arrival intensity and task set size, relationship between total task execution time and single task execution time.

摘要：拓扑节线与节面金属指的是在费米能附近存在能带交叉,并且这些交叉点在动量空间分别形成一维曲线和二维曲面的金属材料.这种特殊的能带结构可以带来很多奇异的物理性质,使得这两类体系在近几年得到了广泛关注.本文着重讨论了节线与节面金属相关概念的发展,回顾了有关的研究工作,包括节线与节面的特征与分类以及相应材料的预测.

摘要：Rational engineering of oxygen vacancy(VO) at atomic precision is the key to comprehensively understanding the oxygen chemistry of oxide materials for catalytic oxidations. Here, we demonstrate that VO can be spatially confined on the surface through a sophisticated surface hydrogen bond(HB) *** HB network is constructed between a hydroxyl-rich Bi OCl surface and polyprotic phosphoric acid,which remarkably decreases the formation energy of surface VO by selectively weakening the metal–oxygen bonds in a short range. Thus, surface-confined VO enables us to unambiguously distinguish the intrafacial and suprafacial oxygen species associated with NO oxidation in two classical catalytic *** randomly distributed bulk VO that benefits the thermocatalytic NO oxidation and lattice O diffusion by the dominant intrafacial mechanism, surface VOis demonstrated to favor the photocatalytic NO oxidation through a suprafacial scheme by energetically activating surface O2, which should be attributed to the spatial confinement nature of surface VO.

摘要：This article summarized the recent advance on the structural design and synthetic strategies of intramolec- ular charge-transfer compounds as well as their potential ap- plications in two-photon absorption chromophores, organic photovoltaics and organic light-emitting diodes.