摘要：Synthetic biology is the process of forward engineering living *** systems can be used to produce biobased materials,agriculture,medicine,and *** approach to designing these systems is to employ techniques from the design of embedded *** techniques include abstraction,standards,modularity,automated design,and formal semantic models of ***,these elements form the foundation of“biodesign automation,”where software,robotics,and microfluidic devices combine to create exciting biological systems of the *** paper describes a“hardware,software,wetware”codesign vision where software tools can be made to act as“genetic compilers”that transform high-level specifications into engineered“genetic circuits”(wetware).This is followed by a process where automation equipment,welldefined experimental workflows,and microfluidic devices are explicitly designed to house,execute,and test these circuits(hardware).These systems can be used as either massively parallel experimental platforms or distributed bioremediation and biosensing ***,scheduling and control algorithms(software)manage these systems’actual execution and data analysis tasks.A distinguishing feature of this approach is how all three of these aspects(hardware,software,and wetware)may be derived from the same basic specification in parallel and generated to fulfill specific cost,performance,and structural requirements.