摘要：目的旨在关注在线教育项目的组成部分和设计,了解为痴呆症患者的家庭照顾者进行在线教育项目的挑战。方法采用Whittemore&Knafl五步法对7个电子数据库进行系统检索。采用混合方法评价工具(Mixed Methods Appraisal Tool)对纳入研究质量进行评价。结果共检索到25256篇文献,最终纳入49项研究。痴呆家庭照顾者在线教育项目在实施过程中的挑战主要包括内容组成(无用或重复的信息,痴呆症相关知识不全面,文化或性别不同对获取内容的影响)、传递形式(互动有限,时间安排受限,对传统信息传递形式的偏好)以及执行(项目技术问题,使用者电子健康素养,保真度评估)3类问题。结论深入了解痴呆症患者家庭照顾者在线教育项目的挑战有助于指导未来的研究者构建最佳在线教育项目。融入文化特色、考虑结构化构建策略、优化互动设计以及增加保真度评估,这些措施可能有助于在线教育项目的实施。

摘要：Abstract Meniscus injury is a common disease in *** it was not treated in time,it leads to osteoarthritis which brings unbearable pain and heavy economic burden to the *** present,meniscectomy and meniscus suture are widely used in the treatment for meniscus ***,It is not ideal for poor self-healing ability of *** recruitment of endogenous stem cells is an attractive option for wounded meniscus *** reduced high-mobility group box 1 protein(HMGB1)can accelerate the regeneration of multiple tissues by endogenous stem cell activation,migration and ***(KGN)has shown to induce the chondrogenesis of the stem ***,no study has explored such effects of HMGB1 and KGN in wounded meniscus ***,in order to improve the regeneration of meniscus,we intend to use a novel bioactive microsphere which was developed by combining fully reduced high mobility group box 1(frHMGB1)and kartogenin(KGN)with alginate gel which slowly release high concentrations of HMGB1 and KGN to activate rat bone marrow stem cells(BMSCs)and promote cell *** results showed that this HMGB1–KGN microsphere released and kept high concentrations of HMGB1 and KGN in the wound area for more than 2 *** vitro experimental results showed that the HMGB1–KGN microsphere can promote cell proliferation via recruiting rat bone marrow stem cells(BMSCs)and activating the BMSCs from G_(0) to G_(Alert) stage as evidenced by cell migration testing and 5-bromo-2′-deoxyuridine(BrdU)incorporation *** vivo results indicated that this HMGB-KGN microsphere can recruit GFP-labeled BMSCs from tail vein to wounded meniscus and induce these GFP-labeled BMSCs to differentiate into *** results demonstrated that the HMGB1–KGN-containing bioactive microsphere induced cell migration in vitro and recruited the cells to wound area to promote wounded rat meniscus healing in vivo.

摘要：Based on the theory of translational action of the functionalism,this paper selects three aspects,translation as an inter-cultural and communicative action,a purposeful text-processing action and an inter-personal action,to analyze the important issues as well as the translation strategies,methods and techniques adopted in the translation of Chinese *** study shows that the theory of translational action is important for the translation of allusions and that it helps to modify the target *** translator,also the author of this paper,hopes that this study will be useful for the translation of allusions and the publicity of traditional Chinese culture across the world.

摘要：针对无人直升机吊装系统在吊运过程中受扰而偏离平衡态的问题,研究了一种基于误差转换函数的鲁棒减摆控制方法。首先建立无人直升机吊装系统的全状态耦合非线性数学模型;其次利用平飞下无人直升机吊装系统的两个理想摆角值和实际摆角值构造了摆角误差,并且研究误差变换函数以保证摆角误差满足预设性能;然后引入非线性干扰观测器估计有界干扰,并且分别基于预设性能方法、干扰观测器的输出和滑模反演方法设计无人直升机吊装系统的鲁棒控制器、速度和姿态子系统的鲁棒控制器;进一步利用构造的李雅普诺夫函数证明了闭环系统稳定性;最后仿真结果表明了控制策略的有效性。