摘要：Data collection with microcrystals at synchrotron radiation facilities is challenging because it is difficult to harvest and locate microcrystals. Moreover,microcrystals are sensitive to radiation damage; thus, typically, a complete data set cannot be obtained with a single microcrystal. Herein, we report a new method for data collection with multiple microcrystals having a crystal size ranging from 1 to 30 lm. This method is suitable for not only low-temperature(100 K) data collection but also room-temperature data collection. Thin Kapton membranes were used to capture multiple crystals simultaneously. The microcrystals were visible under an optical microscope and easily located because the membrane was transparent and sufficiently thin. The film was fixed to a bracket that was prepared using a three-dimensional printer. The bracket was fixed on a magnetic base via screwing and employed by the goniometer system for data collection. Multiple data sets of fatty acid-binding protein 4(FABP4) and lysozyme microcrystals were collected using this novel designed device. Finally, the structures of protein FABP4 and lysozyme were obtained from these data via the molecule replacement method. The data statistics reveal that this method provides a comparable result to traditional methods such as a nylon loop.

摘要：For designing and optimizing the reactor core of modular pebble-bed fluoride salt-cooled high-temperature reactor(PB-FHR),it is of importance to simulate the coupled fluid and particle flow due to strong coolantpebble *** fluid dynamics and discrete element method(DEM) coupling approach can be used to track particles individually while it requires a fluid cell being greater than the pebble ***,the large size of pebbles makes the fluid grid too coarse to capture the complicated flow *** solve this problem,a two-grid approach is proposed to calculate interphase momentum transfer between pebbles and coolant without the constraint on the shape and size of fluid *** solid velocity,fluid velocity,fluid pressure and void fraction are mapped between hexahedral coarse particle grid and tine fluid *** the total interphase force can be calculated independently to speed up *** evaluate suitability of this two-grid approach,the pressure drop and minimum fluidization velocity of a fluidized bed were predicted,and movements of the pebbles in complex flow field were studied experimentally and *** spouting fluid through a central inlet pipe of a scaled visible PB-FHR core facility was set up to provide the complex flow *** was chosen as Liquid to simulate the molten salt coolant,and polypropylene balls were used to simulate the pebble *** show that the pebble flow pattern captured from experiment agrees well with the simulation from two-grid approach,hence the applicability of the two-grid approach for the later PB-FHR core design.

摘要：The intermediate heat exchanger for enhancement heat transfer is the important equipment in the usage of nuclear energy. In the present work, heat transfer and entropy generation of an intermediate heat exchanger(IHX) in the accelerator driven subcritical system(ADS) are investigated experimentally. The variation of entropy generation number with performance parameters of the IHX is analyzed, and effects of inlet conditions of the IHX on entropy generation number and heat transfer are discussed. Compared with the results at two working conditions of the constant mass flow rates of liquid lead-bismuth eutectic(LBE) and helium gas, the total pumping power all tends to reduce with the decreasing entropy generation number, but the variations of the effectiveness, number of transfer units and thermal capacity rate ratio are inconsistent, and need to analyze respectively. With the increasing inlet mass flow rate or LBE inlet temperature, the entropy generation number increases and the heat transfer is enhanced, while the opposite trend occurs with the increasing helium gas inlet temperature. The further study is necessary for obtaining the optimized operation parameters of the IHX to minimize entropy generation and enhance heat transfer.

摘要：Pebble bed reactors enable the circulation of pebble fuel elements when the reactors are in *** unique design helps to optimize the burnup and power distribution, reduces the excessive reactivity of the reactor,and provides a mean to identify and segregate damaged fuel elements during operation. The movement of the pebbles in the core, or the kinematics of the pebble bed,significantly affect the above features and is not fully understood. We designed and built a detection system that can measure 3-axis acceleration, 3-axis angular velocity,3-axis rotation angles, and vibration and temperature of multiple pebbles anywhere in the pebble bed. This system uses pebble-shaped detectors that can flow with other pebbles and does not disturb the pebble movement. We used new technologies to enable instant response, precise measurement, and simultaneous collection of data from a large number of detectors. Our tests show that the detection system has a negligible zero drift and the accuracy is better than the designed value. The residence time of the pebbles in a moving pebble bed was also measured using the system.

摘要：The study of accelerator-driven subcritical reactor systems(ADSs) has been an important research topic in the field of nuclear energy for years. The main code applied in ADS research is MCNPX, which was developed by Los Alamos National Laboratory. We studied the application of the open-source Monte Carlo codes FLUKA and OpenMC to a coupled ADS calculation. The FLUKA code was used to simulate the reaction of highenergy protons with the nucleus of the target material in the ADS, which produces spallation neutrons. Information on the spallation neutrons, such as their energy, position,direction, and weight, can be recorded by a user-defined routine called FLUSCW provided by FLUKA. Then, the information was stored in an external neutron source file in HDF5 format by using a conversion code, as required by the OpenMC calculation. Finally, the fixed-source calculation function of OpenMC was applied to simulate the transport of spallation neutrons and obtain the distribution of the neutron flux in the core region. In the coupled calculation, the high-energy cross-section library JENDL4.0/HE in ACE format produced by NJOY2016 was applied in the OpenMC transport simulation. The OECD–ADS benchmark problem was calculated, and the results were compared with those obtained using MCNPX. It was found that the flux calculations performed by FLUKA–OpenMC and MCNPX were in agreement, so the coupling calculation method for ADS is reasonable and feasible.

摘要：Depletion calculation is important for studying the transmutation efficiency of minor actinides and longlife fission products in accelerator-driven subcritical reactor system(ADS). Herein the Python language is used to develop a burnup code system called IMPC-Burnup by coupling FLUKA, OpenMC, and ORIGEN2. The program is preliminarily verified by OECD-NEA pin cell and IAEAADS benchmarking by comparison with experimental values and calculated results from other studies. Moreover,the physics design scheme of the CIADS subcritical core is utilized to test the feasibility of IMPC-Burnup program in the burnup calculation of ADS system. Reference results are given by the COUPLE3.0 program. The results of IMPC-Burnup show good agreement with those of COUPLE3.0. In addition, since the upper limit of the neutron transport energy for OpenMC is 20 MeV, neutrons with energies greater than 20 MeV in the CIADS subcritical core cannot be transported; thus, an equivalent flux method has been proposed to consider neutrons above 20 MeV in the OpenMC transport calculation. The results are compared to those that do not include neutrons greater than 20 MeV. The conclusion is that the accuracy of the actinide nuclide mass in the burnup calculation is improved when the equivalent flux method is used. Therefore, the IMPC-Burnup code is suitable for burnup analysis of the ADS system.

摘要：A new special coupler with a kind of bowl-shaped ceramic window for a proton linear accelerator named the chinese Accelerator Driven System （C-ADS） at the Institute of Modern Physics （IMP） has been simulated and constructed and a continuous wave （CW） beam commissioning through a four-meter long radio frequency quadruple （RFQ） was completed by the end of July 2014. In the experiments of conditioning and beam, some problems were promoted gradually such as sparking and thermal issues. Finally, two new couplers were passed with almost 110 kW CW power and 120 kW pulsed mode, respectively. The 10 mA intensity beam experiments have now been completed, and the couplers during the operation had no thermal or electro-magnetic problems. The detailed design and results are presented in the paper.

摘要：For the chinese-ADS project, to provide enough neutrons to drive the subcritical system, tens of MW spallation targets for the C-ADS are necessary. This is not an easy task. Here we propose a new concept for a gravity-driven dense granular flow target, in which heavy metal grains are chosen as the spallation target material. Compared with currently widely used targets, this conceptual design has advantages with regard to heat removal, thermal shock protection, neutron yield, radiotoxicity reduction, and convenient operation. The gravity-driven dense granular flow target has the potential to easily deal with these issues and to form a foundation for tens of MW spallation targets for cost-effective facilities. Preliminary simulations and experiments have been completed to support this conceptual design.

摘要：Molten salt pebble bed reactor is one of the sixth-generation Ⅳ reactor types. To investigate the mechanical behavior of the fuel pebbles in the core, a visualization experiment facility of pebble bed(VEFPB) is designed. To obtain a uniform flow field of the core and analyze the influence of the flow field on the structure of the pebble bed, computational fluid dynamics software Fluent is used to simulate the flow field distribution of the core of VEFPB. The simulation results show that the disturbance at the bottom of the pebble bed is proportional to the flow velocity of the inlet pipe, and the flow velocity close to the inlet side is more significant than that in other parts; the design of the cylinder bottom plate with holes of different sizes can effectively reduce the flow velocity and the disturbance at the bottom of the pebble bed. In addition,according to the velocity contours of the core of VEFPB, it is observed that the flow field distribution of the core is considerably uniform except at the bottom of the pebble bed. This ensures the stability of the pebble bed and verifies the rationality of the design of VEFPB. This study provides the technical support and reference for the flow field analysis of the core of molten salt pebble bed reactor.

摘要：Pathogen/microbe-associated molecular patterns(PAMPs/MAMPs) are recognized by plant pattern recognition receptors(PRRs)localized on the cell surface to activate immune *** PAMP-triggered immunity(PTI) confers resistance to a broad range of pathogenic microbes and,therefore,has a great potential for genetically engineering broad-spectrum resistance by transferring PRRs across plant *** effectors secreted by phytopathogens often directly target and inhibit key components of PTI signaling pathways via diverse biochemical *** some cases,plants have evolved to produce decoy proteins that mimic the direct virulence target,which senses the biochemical activities of pathogenic *** kind of perception traps the effectors of erroneous targeting and results in the activation of effector-triggered immunity(ETI) instead of suppressing *** mechanism suggests that artificially designed decoy proteins could be used to generate new recognition specificities in a particular *** this review,we summarize recent advances in research investigating PAMP recognition by PRRs and virulence effector surveillance by decoy *** expansion of recognition specificities,conferred by the transgenic expression of EF-Tu receptor(EFR) and AvrPphB susceptible 1(PBS1) decoys,has highlighted the considerable potential of PRRs and artificially designed decoys to expand plant resistance spectra and the need to further identify novel PRRs and decoys.