摘要：According to the study on seat-back curves about different people, the method that using two arc-shaped roofs to give back supporting force of the human body is proposed. Through a clever design application of piezoelectric sensor, microcontroller, motors, and arc-shaped roofs form a closed loop control system. Through the design of horizontal and vertical adjustment mechanism, a flexible and adaptive multi-dimensional back can reduce the harm to human spine which caused by poor posture and sedentary life style. Model building and stress analysis are done by Inventor software to verify the mechanism of strength.

摘要：多模态疗法是结合多种疗法治疗通常复杂而隐蔽的肿瘤组织的最有希望的策略之一.尽管多功能纳米材料已被设计用于构建多模态疗法,但普遍存在的各组成部分之间的不充分协调可能导致协同治疗效果不佳,并妨碍其充分实现临床潜力.在此,受可控“集束炸弹”模型的启发,我们设计了一种智能、生物相容、多功能的纳米工厂系统(PDA@GOx@MnO_(2)-PEG),它封装了多种纳米试剂,以达到对肿瘤组织的高破坏效率.刺激反应性的外层二氧化锰作为“炸弹”的外壳可触发级联催化反应,并与GOx形成一个自给自足的环形催化链.PDA作为一种具有良好蛋白质携带能力的基质,实现了高的GOx负载.同时,其高效的光热转换效率显示了低温(~45℃)进一步提高GOx酶活性的潜力.值得注意的是,内部的GOx就像一个“子炸弹”,通过控制释放来增加肿瘤缺氧部位的积累,并在充足的氧气和低热度的帮助下充分发挥其葡萄糖消耗能力进行饥饿治疗.在这个体系中,各种纳米试剂相互配合,层层推进,充分发挥其威力,形成了一个自给自足的纳米工厂模型,通过协同策略实现了良好的低温光热-饥饿协同治疗.此外,该纳米复合材料表现出三态成像能力,可用于敏感诊断和实时监控治疗.这项研究为设计生物相容性和智能治疗纳米平台提供了新的见解,使精准医疗中的多模式治疗效果最大化.

摘要：分析了无线传感器网络功率控制机制,归纳总结了设计原则和分类方法,详细介绍了当前典型功率控制算法的核心机制,并比较分析了这些算法的类别、特点和性能差异.最后结合领域内的研究现状,指出了限制无线传感器网络实用化的问题所在,提出了基于实验研究和统计分析方法建立自适应功率控制模型与实现策略的重要性.

摘要：核孔蛋白(Nucleoporins,Nups)是核孔复合体(Nuclear pore complexes,NPC)的重要组成成分,核孔复合体可以 控制细胞内信号分子在核质间的双向转运,从而控制基因表达、细胞增殖和分化。在构建的黄鳝精巢SMART cDNA文库 中,采用差异筛选的方法得到黄鳝核孔蛋白家族中Nup93基因的3′端片段,根据此段序列设计引物,使用兼并PCR和5′RACE 方法克隆得到此基因的全长cDNA。序列比对显示该基因与酵母Nic96、斑马鱼Nup93和人类Nup93的同源性分别为36．5％、 94．6％和90．5％。进化树分析显示,黄鳝Nup93与其他鱼类的Nup93归为一支。采用荧光定量PCR方法对不同性别黄鳝的 性腺和其他组织内该基因的表达作定量分析发现,Nup93在性腺和肾中的表达量远高于其他组织,而且表达量存在一定的 性别差异。这一结果提示Nup93可能与性腺发育相关。

摘要：To enable real-time flight visualization for junior operators,this paper designs a quadrotor flight system via computer *** aircraft’s three-dimensional model and the flight scene are generated using open graphics library(OpenGL).Attitude angle of the model are calculated using the mathematical model of the *** flight system provides an intuitive way to describe the flight according to real-time data input from the controller.

摘要：VPAC1是垂体腺苷酸环化酶激活多肽(pituitary adenylate cyclase-activating polypeptide,PACAP)和血管活性肠肽(vasoactive intestinal polypeptide,VIP)的共同受体。VPAC1介导PACAP和VIP抑制食欲和抗炎的生物学功能。本研究体外实验表明,VPAC1在分化成熟的3T3-L1脂肪细胞中表达增高,并且VPAC1激动剂(10～1000nmol/L每1×106cells)可诱导脂肪细胞脂解,因此我们预计VPAC1激动剂具有抗肥胖及肥胖综合征的作用。为研究VAPC1激动剂[Lys15,Arg16,Leu27]-VIP(1-7)GRF(8-27)对营养性肥胖及肥胖综合征的干预作用,本研究又设计了两组体内实验:(1)高脂喂养NIH雄性小鼠4周,同时腹腔注射VPAC1激动剂;以注射生理盐水作为对照;(2)高脂喂养NIH雄性小鼠5周,构建肥胖模型后,再腹腔注射VPAC1激动剂4周,同样以注射生理盐水作为对照。采集摄食、体重、体脂、血糖及血脂等指标。结果显示,VPAC1激动剂显著抑制摄食、抑制高脂饮食诱导的体重及体脂(附睾及背部)重量的增长,并有效改善高脂饮食诱导的高血糖及高血脂,提高机体的糖耐受。高剂量(每天50nmol/kg体重)VPAC1激动剂比低剂量(每天5nmol/kg体重)有更显著的抗肥胖作用,提示VPAC1激动剂的抗肥胖作用具有剂量依赖性。以上结果表明,VPAC1激动剂不仅能抑制高脂诱导的肥胖的发展,而且可有效改善肥胖相关疾病;其抗肥胖作用的机制是复杂整合的,值得进一步深入研究。

摘要：In this paper, the hybrid electric vehicle braking process is researched, by using variables consists of HEV speed, motor speed, and state of charge established, fimctions of mechanical braking force, regenerative braking force and efficiency of energy recovery are constructed, and the control goal is to maximization the energy recovery efficiency. Under the feedback control strategy, with the constrain condition of braking strength and braking stability, combining experiments in ADVISOR, in different experiments of different working conditions, we can see that in UDDS Cycle, the regenerative braking efficiency is the best. What＇s more, compared with strategies in ADVISOR, strategy proposed in this paper is obviously better.

摘要：A vehicle intelligent terminal is designed to collect vehicle state information and driver behavior information based on the application of Internet of Vehicle in the insurance industry, and data of 12 risk factors affecting the traffic safety is extracted from the information. The Principal Component Analysis is improved and PCA based on the index significant priority is proposed, using which the data of risk factors is processed and 3 principal components are obtained as the pricing factor of the insurance industry.

摘要：通过对模型化合物环四-9,9'-二甲基-2,7-芴及其系列的环芴衍生物[n]CFs(n=3-8)的结构、张力能以及光电性质的研究来进一步探讨空间张力对材料光学及电学性质的影响。研究结果表明,随着化合物中芴基数量和直径的增加,张力能减小,能隙增大。具有相同芴基数目的环芴分子,随着分子中张力能减少,分子电离电势逐渐增加,而电子亲和能逐渐减小。通过对模型化合物的空穴和电子重整能研究发现,其数值很接近,说明该类材料是一类潜在的双极性传输材料。同时还发现[n]CFs中,随着张力的减少,其第二发射峰的波长发生了蓝移。综上所述,空间张力为设计多功能有机半导体材料提供了有力工具。

摘要：This work introduces a scalable and efficient topological structure for tetrahedral and hexahedral meshes. The design of the data structure aims at maximal flexibility and high performance. It provides a high scalability by using hierarchical representa-tions of topological elements. The proposed data structure is array-based, and it is a compact representation of the half-edge data structure for volume elements and half-face data structure for volumetric meshes. This guarantees constant access time to the neighbors of the topological elements. In addition, an open-source implementation named Open Volumetric Mesh （OVM） of the pro-posed data structure is written in C＋＋ using generic programming concepts.