摘要：The effect of a terrestrial humic acid （HA） and Suwannee River HA on the cytotoxicity of engineered zinc oxide nanoparticles （ZnONps） and titanium dioxide nanoparticles （TiO2Nps） to natural aquatic bacterial assemblages was measured with spread plate counting. The effect of HA （10 and 40 ppm） on the cytotoxicity of ZnONps and TiO2Nps was tested factorially in the presence and absence of natural sunlight （light irradiation （LI））. The experiment was of full factorial, completely randomized design and the results were analyzed using the General Linear Model in SAS analytical software. The method of least squares means was used to separate the means or combinations of means. We determined the mechanism of toxicity via measurements of oxidative stress and metal ions. The toxicity of ZnONps and TiO2Nps to natural aquatic bacterial assemblages appears to be concentration dependent. Moreover, the cytotoxicity of ZnONps and TiO2Nps appeared to be affected by HA concentration, the presence of sunlight irradiation, and the dynamic multiple interactions among these factors. With respect to light versus darkness in the control group, the data indicate that bacterial viability was inhibited more in the light exposure than in the darkness exposure. The same was true in the HA treatment groups. With respect to terrestrial versus Suwanee River HA for a given nanoparticle, in light versus darkness, bacterial viability was more inhibited in the light treatment groups containing the terrestrial HA than in those containing Suwanee River HA. Differences in the extent of reactive oxygen species formation, adsorption/binding of ZnONps/TiO2Nps by HA, and the levels of free metal ions were speculated to account for the observed cytotoxicity. TEM images indicate the attachment and binding of the tested nanoparticles to natural bacterial assemblages. Besides the individual parameter, significant effects on bacterial viability count were also observed in the following combined treatments： HA-Zn

摘要：Aluminium alloy AA2219 is a high strength alloy belonging to 2000 series. It has been widely used for aerospace applications, especially for construction of cryogenic fuel tank. However, arc welding of AA2219 material is very critical. The major problems that arise in arc welding of AA2219 are the adverse development of residual stresses and the re-distribution as well as dissolution of copper rich phase in the weld *** effects increase with increase in heat input. Thus, special attention was taken to especially thick section welding of AA2219-T87 aluminium alloy. Hence, the present work describes the 25 mm-thick AA2219-T87 aluminium alloy plate butt welded by GTAW and GMAW processes using multi-pass welding procedure in double V groove design. The transverse shrinkage, conventional mechanical and metallurgical properties of both the locations on weld joints were studied. It is observed that the fair copper rich cellular(CRC) network is on Side-A of both the weldments. Further, it is noticed that, the severity of weld thermal cycle near to the fusion line of HAZ is reduced due to low heat input in GTAW process which results in non dissolution of copper rich phase. Based on the mechanical and metallurgical properties it is inferred that GTAW process is used to improve the aforementioned characteristics of weld joints in comparison to GMAW process.

摘要：The diverse non-smooth body surfaces to reduce soil adhesion are the evolutional results for the soil animals to fit the adhesive and wet environment and can be used as a biological basis for the design of bionic plow moldboard. The model surfaces for bionic simulation should be taken from soil animal digging organs, on which the soil motion is similar to what is on the surface of moldboard. By analyzing the distribution of non-smooth units on the body surface of the ground beetle jaw and the soil moving stresses, the design principles of the bionic moldboard for the local and the whole moldboard were presented respectively. As well, the effect of soil moving speed on reducing adhesion, the dimensions relationship between soil particles and non-smooth convexes, the relationship between the enveloping surface of non-smooth convexes and the initial smooth surface of the plow body, and the convex types of the sphere coronal and the pangolin scales,*** discussed.

摘要：为了应对芯片设计复杂度的提升,电子设计自动化工具和方法也在不断进步。然而,EDA需要协调达到最佳的功率、性能和面积,通常其不能保证最优的解决方案。EDA工具在电路设计阶段包括逻辑综合、布局布线及验证等均属于多目标、多约束的非线性规划求解过程,且为了更好解决求解中的不确定性和易于出现局域极值等难题,基于神经网络的优化算法已被集成到EDA工具的设计流程中。首先对EDA中的优化问题、多目标优化计算及基于神经网络的优化算法进行了简要概述,继而详细梳理了基于神经网络的优化算法在逻辑综合、布局布线及验证等不同设计阶段中的优化求解方法,并阐述了当前研究所面临的挑战与机遇,希望为集成电路自动化设计及相关领域研究提供参考。

摘要：Fungi are nature’s recyclers,allowing for ecological nutrient cycling and,in turn,the continuation of life on *** fungi inhabit the human microbiome where they can provide health benefits,while others are opportunistic pathogens that can cause ***,members of the fungal kingdom,have been domesticated by humans for the production of beer,bread,and,recently,medicine and ***,the great untapped potential exists within the diverse fungal ***,many yeasts are intractable,preventing their use in biotechnology or in the development of novel treatments for pathogenic ***,as a first step for the domestication of new fungi,an efficient DNA delivery method needs to be ***,we report the creation of superior conjugative plasmids and demonstrate their transfer via conjugation from bacteria to 7 diverse yeast species including the emerging pathogen Candida *** create our superior plasmids,derivatives of the 57 kb conjugative plasmid pTA-Mob 2.0 were built using designed gene deletions and insertions,as well as some unintentional ***,a cluster mutation in the promoter of the conjugative gene traJ had the most significant effect on improving conjugation to *** addition,we created Golden Gate assembly-compatible plasmid derivatives that allow for the generation of custom plasmids to enable the rapid insertion of designer genetic ***,we demonstrated that designer conjugative plasmids harboring engineered restriction endonucleases can be used as a novel antifungal agent,with important applications for the development of next-generation antifungal therapeutics.

摘要：在日、美、韩等国，以人的创意为主要特征的动漫产业。其产值已经超过了钢铁、石油等传统产业产值，成为国民经济的支柱产业。国外动漫画大举进入我国．直接威胁着我国的文化安全和优秀传统文化的传承与青少年民族精神的培育。

摘要：由于当前市场上没有既适合大田大面积灌溉、混肥精度又高的水肥一体化系统,故在旁路式结构设计中增加静态混合器替换主管道,以提高混肥均匀性为重点进行研究,对混肥部件进行了优化改进。利用混合器自身结构,在不需要外接能源的条件下,使得水肥充分混合,不仅能够满足大面积灌溉要求,而且可以保证混肥精度。基于流体力学及CFD基本原理,通过Fluent软件分析水肥混合过程中SK型静态混合器混合单元数,以及长径比对水肥混合性能和压降的影响,以此找出混合器的最佳结构参数,并对其结构做了改进,设计出了开沟式静态混合器。

摘要：针对传统电力设备红外图像超分辨率重建方法缺乏对设备局部纹理特征和全局温度分布的考虑导致重建后图像分辨率较低的问题,提出一种基于Transformer-GAN聚合网络的电力设备超分辨率重建方法。首先,基于移位卷积设计电力设备局部特征提取模块,在不增加参数情况下扩展卷积的感受野,提取电力设备局部纹理及其周围不同空间维度特征的信息。然后,引入全局特征提取模块,通过深度卷积和空间注意力机制捕捉图像不同区域间温度分布的关联性。最后,采用UNet编解码器网络融合各层局部特征和全局表示,生成清晰自然的电力设备红外图像。算例结果表明,所提方法的峰值信噪比(peak signal-to-noise ratio,pSNR)、结构相似性(structural similarity,SSIM)、和视觉信息保真度(visual information fidelity,VIF)三项评价指标均优于其他方法。同时它具有良好的主观视觉效果,泛化能力较强。

摘要：面向室内定位基站部署需求,针对测距型基站室内组网定位的主要影响因素,全面研究了多种网形在不同条件下的定位特性,率先提供了室内定位基站组网的参考原则和定位性能特征。通过设计不同形状、尺度、高度、规模的基站组网方案,完成了基站定位性能研究。结果表明:(1)圆形基站网位置精度因子优于方形网,直线形基站网不适宜进行三维定位服务。(2)基站网半径增加一倍,位置精度因子均值减小一倍。(3)基站网的高度增大一倍,其垂直和位置精度因子均值减小1/3。(4)圆形网的基站数增大一倍,位置精度因子均值减小1/3。(5)基站网高度约为1/2服务区域半径时,平面和垂直定位精度达到均衡。沿区域边界上空均匀部署6个以上基站时,平面和垂直精度因子优于1。上述基站组网原则和定位性能特征,将为室内定位系统基站部署的形状、高度、数量、半径等设计工作提供有力支撑。