摘要：Fixed-bed reactors randomly packed with catalysts have many disadvantages that may adversely affect the desired chemical *** increasingly used monolithic reactor,in contrast,has many operational advantages;however,for a kinetically-controlled reaction,it does not contain sufficient catalyst to sustain the *** address the problems associated with both randomly packed-bed reactor and the monolithic reactor,a structured packed-bed reactor was proposed and mathematical models were built for randomly packed-bed reactor and structured packed-bed *** respective performances were compared when applied to the exothermic reaction of the isopropanol-acetone-hydrogen chemical heat pump *** results showed that the structured packed-bed reactor performed better in terms of pressure drop and heat transfer capacity,and had a lower radial temperature gradient,indicating that this reactor had a higher effective heat *** on the catalyst particle surfaces was more concentrated near the tube wall because a wall effect existed in the boundary layer around the particle-wall contact points.

摘要：An experimental investigation on the unsteady tip flow field of a transonic compressor rotor has been *** casing-mounted high frequency response pressure transducers were arranged along both the blade chord and the blade *** chord-wise ones were used to indicate both the ensemble averaged and time varying flow structure of the tip region of the rotor at different operating points under 95% design speed and 60% design *** pitch-wise circumferential transducers were mainly used to analyze the unsteadiness frequency of the tip leakage flow in the rotor frame at the near stall *** contours of casing wall pressure show that there were two clear low pressure regions in blade passages,one along the chord direction,caused by the leakage flow and the other along the tangential direction,maybe caused by the forward swept leading *** low pressure regions were originated from the leading edge and formed a scissor-like flow *** 95% design speed condition,the shock wave interacted with the low pressure region and made the flow field *** the mass flow reduced,the two low pressure regions gradually contracted to the leading edge and then a spike disturbance emerged.

摘要：Topology optimization of continuum structures with design-dependent loads has long been a challenge. In this paper, the topology optimization of 3D structures subjected to design-dependent loads is investigated. A boundary search scheme is proposed for 3D problems, by means of which the load surface can be identified effectively and efficiently, and the difficulties arising in other approaches can be overcome. The load surfaces are made up of the boundaries of finite elements and the loads can be directly applied to corresponding element nodes, which leads to great convenience in the application of this method. Finally, the effectiveness and efficiency of the proposed method is validated by several numerical examples.

摘要：By choosing neuroimmunophilin FKBP12 as a therapeutical target, we have attempted to discover a new structural drug for treating neurodegenerative disease. This drug should possess neurotrophic activity and not affect the immune system. Based on the crystal structure of FKBP12, FK506 and Calcineurin complex, a series of small organic molecules were designed. These molecules were to have the ability of binding to FKBP12 in a virtual screening. By using a solution parallel synthetic method, these compounds were synthesized. The neuroprotective and neuroregenerative activities of these compounds were evaluated by binding assays, PC12 cells survival and neurite outgrowth model, chick dorsal root ganglion cultures (DRG) and 6-OHDA lesioned mice sympathetic nerve endings model. The evaluation results of these compounds showed that compound N308 has great promise as a candidate for a neuroprotective and neuroregenerative agent.

摘要：Phenological data obtained from historical documents constitute highly important ecological evidence for the pre-instrumental period, and can be used in analyzing climatic change in history. In this study, 87 phenological records about seasonality of non-biological events （e.g., first frost date）, agriculture and ornamental plants （e.g., first flowering date） over 77 years were extracted from historical documents from the Sui and Tang dynasties in china to reconstruct the winter half-year （from October to next April） temperatures in the Guanzhong Area （located in central china） from 600 to 902 AD. Transfer functions between temperature and phenophases with significant correlations were established by using modem observation data. Temperatures from the study period were reconstructed by applying the transfer functions to historical phenological data. The reconstruction indicates that the winter half-year temperatures during 600-902 AD were 0.23~C higher than the reference period （1961-1990）. The temperature changed with two distinct stages. During the 600s-800s, temperatures were approxi- mately 0.38~C higher than at present but then temperatures decreased in the subsequent period （800-902 AD）. These results are similar to ones from previous studies on the mean temperature and the divisions between warm and cold periods during the study period, though differences were found in the degree of warmness/coldness. This reconstruction provides a valuable contribution to a better understanding of climatic variability during the Sui and Tang dynasties in china.

摘要：A new concept of photonic crystal fiber（PCF） with high nonlinearity and flattened dispersion was designed. The PCF structure is indeed a hexagon lattice. The bigger air holes in the outer rings are used to confine the light field into the core region for enhancing the nonlinearity. The flattened dispersion can be achieved by adjusting the diameters of six smaller air holes in the first ring, and six micro air holes are inserted between smaller air holes for higher nonlinearity and the better flattened dispersion. By optimizing the size of the smaller and micro holes, the PCF can reach to high nonlinearity of 23.3 W-1·km^-1 and the low dispersion of 51.32 ps/（nm·km） with the fluctuation range of 0.98 ps/（nm·km）, which is within the wavelength range of 1 400 nm to 1 900 nm. The designed PCF can be used in important applications in realizing the Raman soliton self-frequency shift（RSSFS）.

摘要：A series of Ti-Zr-Be-Fe bulk metallic glasses(BMGs)with good glass-forming ability(GFA)and high specific strength have been *** different alloying routes and content of Fe,it is found that these alloys exhibit different GFA and mechanical *** effects of Fe addition on the GFA and mechanical properties of Ti-Zr-Be alloy are systemically *** possible mechanisms for the improvement or damage to the GFA by addition of Fe can be interpreted in view of the mixing enthalpy,atomic size differences and electronegativity differences of the alloys,while the mechanical properties strongly depend on the Poisson’s ratio and free volume *** experimental results also show that alloying technology is an effective method to improve the GFA and mechanical properties of Ti-Zr-Be glassy alloy.

摘要：As a special type of novel flexible structures, tensegrity holds promise for many potential applications in such fields as materials science, biomechanics, civil and aerospace engineering. Rhombic systems are an important class of tensegrity structures, in which each bar constitutes the longest diagonal of a rhombus of four strings. In this paper, we address the design methods of rhombic structures based on the idea that many tensegrity structures can be constructed by assembling one-bar elementary cells. By analyzing the properties of rhombic cells, we first develop two novel schemes, namely, direct enumeration scheme and cell-substitution scheme. In addition, a facile and efficient method is presented to integrate several rhombic systems into a larger tensegrity structure. To illustrate the applications of these methods, some novel rhombic tensegrity structures are constructed.

摘要：New pH-responsive saccharide hydrogels were designed and prepared using curdlan derivatives（curdlan-Bochistidine, CUR-HIS）. The CUR-HIS hydrogels possessed highly porous structures. The swelling ratios of CUR-HIS hydrogels increased with the degree of substitution of Boc-histidine groups. And the addition of 0.5 mol/L Na Cl provoked a sharp reduction of swelling ratio of CUR-HIS hydrogels. Bovine serum albumin（BSA） can be efficiently encapsulated into CUR-HIS hydrogels. Moreover, the release profiles of BSA at different p H values from CUR-HIS hydrogels were significantly different. These hydrogels showed good biocompatibility in the cytotoxicity assays. The CUR-HIS hydrogels are of great potential in biomedical applications such as protein delivery systems.

摘要：With the development of the compressive sensing theory, the image reconstruction from the projections viewed in limited angles is one of the hot problems in the research of computed tomography technology. This paper develops an iterative algorithm for image reconstruction, which can fit the most cases. This method gives an image reconstruction flow with the difference image vector, which is based on the concept that the difference image vector between the reconstructed and the reference image is sparse enough. Then the l1-norm minimization method is used to reconstruct the difference vector to recover the image for flat subjects in limited angles. The algorithm has been tested with a thin planar phantom and a real object in limited-view projection data. Moreover, all the studies showed the satisfactory results in accuracy at a rather high reconstruction speed.