摘要：A multilayer perceptron(MLP) artificial neural network(ANN) model has been optimized by the multi-objective ant colony optimization(MOACO) algorithm, which uses three objective functions. A sensitivity analysis to choose MOACO parameter values is carried out by calculating hypervolume metric, and the proposed approach adopts the Vlsekriterijumska Optimizacija I Kompromisno Resenje(VIKOR) decision method to choose final compromised solution on the Pareto front obtained from MOACO. As a result, we used the MLP-MOACO developed model to estimate the value of engine emissions of NOxin a four stroke, spark ignition(SI) gasoline engine and observed acceptable correlation coefficient(R^2) of 0.99978.

摘要：Although several research works in the literature have focused on studying the capabilities of additive manufacturing(AM) systems, few works have addressed the development of Design for Additive Manufacturing(DfAM) knowledge,tools, rules, and methodologies, which has limited the penetration and impact of AM in industry. In this paper a comprehensive review of design and manufacturing strategies for Fused Deposition Modelling(FDM) is ***, several DfAM strategies are proposed and analysed based on existing research works and the operation principles, materials, capabilities and limitations of the FDM process. These strategies have been divided into four main groups: geometry, quality, materials and sustainability. The implementation and practicality of the proposed DfAM is illustrated by three case studies. The new proposed DfAM strategies are intended to assist designers and manufacturers when making decisions to satisfy functional needs, while ensuring manufacturability in FDM ***, many of these strategies can be applied or extended to other AM processes besides FDM.

摘要：The production of thermostable laccases from a native strain of the white-rot fungus Pycnoporus sanguineus isolated in mexico was enhanced by testing different media and a combination of inducers including copper sulfate（CuSO4）.The best conditions obtained from screening experiments in shaken flasks using tomato juice,CuSO4,and soybean oil were integrated in an experimental *** levels of tomato juice as the medium,CuSO4and soybean oil as inducers（36.8%（v/v）,3 mmol/L,and 1%（v/v）,respectively） were determined for 10 L stirred tank bioreactor *** combination resulted in laccase titer of 143000 IU/L（2,2＇-azino-bis（3-ethylbenzthiazoline-6- sulfonic acid）,pH 3.0）,which represents the highest activity so far reported for *** in a 10-L *** interesting media resulting from the screening included glucose-bactopeptone which increased laccase activity up to 20000 IU/L,whereas the inducers Acid Blue 62 and Reactive Blue 19 enhanced enzyme production in this medium 10 *** on a partial characterization,the laccases of this strain are especially promising in terms of thermostability（half-life of 6.1 h at 60 °C） and activity titers.