摘要：With the development of technology,the learning and memory functions of artificial memristor synapses are necessary for realizing artificial neural networks and neural neuromorphic *** to their high scalability performance,nanosheet materials have been widely employed in cellular-level learning,but the behaviors of nociceptor based on nanosheet materials have rarely been ***,we present a memristor with an Al/TiO_(2)/Pt *** electroforming,the memristor device showed a gradual conductance regulation and could simulate synaptic functions such as the potentiation and depression of synaptic *** also designed a new scheme that verifies the pain sensitization,desensitization,allodynia,and hyperalgesia behaviors of real nociceptors in the fabricated *** with these behaviors can significantly improve the quality of intelligent electronic *** fitting showed that the high resistance and low resistance states were consistent with the hopping conduction *** work promises the application of TiO_(2)-based devices in next-generation neuromorphological systems.