摘要：Personalized drugs,as well as disease-specific and condition-dependent drug release,have been highly desired in drug delivery systems for effective and safe ***-dimensional(4 d)printing,as a newly emerging technique to develop drug capsules,displays unique advantages that can autonomously control drug release according to the actual physiological ***,core-shell structured hydrogel capsules were developed using a multimaterial extrusion-based 4 d printing method,which consists of a model drug as the core and UV cross-linked poly(N-isopropylacrylamide)(PNIPAM)hydrogel as the *** to the lower critical solution temperature(LCST)-induced shrinking/swelling properties,the prepared PNIPAM hydrogel capsules showed temperature-responsive drug release along with the topography changes in the cross-linked PNIPAM *** in vitro drug release test confirmed that the PNIPAM hydrogel capsules can autonomously control their drug release behaviors according to changes in ambient ***,the increased shell thickness of these capsules causes an obvious reduction in drug release rate,distinctly indicating that the drug release behavior can be well adjusted by setting the shell thickness of the *** proposed 4 d printing strategy pioneers the paradigm of smart drug release by showing great potential in the smart controlled release of drugs and macromolecular active agents.

摘要：The one-ladle technology requires an efficient ironmaking and steelmaking interface. The scheduling of the hot metal ladle in the steel plant determines the overall operational efficiency of the interface. Considering the strong uncertainties of real-world production environments, this work studies the dynamic scheduling problem of hot metal ladles and develops a data-driven three-layer approach to solve this problem. A dynamic scheduling optimization model of the hot metal ladle operation with a minimum average turnover time as the optimization objective is also constructed. Furthermore, the intelligent perception of industrial scenes and autonomous identification of disturbances, adaptive configuration of dynamic scheduling strategies, and real-time adjustment of schedules can be realized. The upper layer generates a demand-oriented prescheduling scheme for hot metal ladles. The middle layer adaptively adjusts this scheme to obtain an executable schedule according to the actual supply–demand relationship. In the lower layer, three types of dynamic scheduling strategies are designed according to the characteristics of the dynamic disturbance in the model:real-time flexible fine-tuning, local machine adjustment, and global rescheduling. Case test using 24 h production data on a certain day during the system operation of a steel plant shows that the method and system can effectively reduce the fluctuation and operation time of the hot metal ladle and improve the stability of the ironmaking and steelmaking interface production rhythm. The data-driven dynamic scheduling strategy is feasible and effective, and the proposed method can improve the operation efficiency of hot metal ladles.

摘要：Cam-lobe radial-piston hydraulic motors are widely used in large machinery due to their excellent capability to withstand high loading at low ***,the line contact between the roller and cam ring generates elastic deformation of the cam ring under high loading,leading to obvious speed and torque pulsations and even the detrimental crawl problem of hydraulic *** address this issue,we propose a deformation pre-compensated optimization design approach to compensate for the cam ring deformation in advance,thereby eliminating the influence of cam ring deformation on the hydraulic motor’s *** this approach,the design process is divided into two steps:first,the overall profile of the cam ring is optimized based on the calculated elastic deformation;second,the local profile of cam ring is further optimized until the hydraulic motor’s pulsations no longer ***,a case study is carried out to verify the effectiveness of this *** result indicates the pulsation rate of a deformation pre-compensated cam ring is 40%lower than that of an uncompensated *** study offers an easy and feasible way to design an optimized cam ring profile for low pulsation hydraulic motors.

摘要：Fast migration and efficient spatial separation of photogenerated charges in photocatalytic materials are indispensable to efficient solar water splitting ***,we construct a three-phase heterostructure of CdS/PbTiO_(3)/TiO_(2)by selectively depositing CdS and TiO_(2)at oppositely poled crystal facets of PbTiO_(3)using single-domain ferroelectric PbTiO_(3).The heterostructure has matching band edge alignments and strong interfacial connections at different *** heterostructure combines the interfacial electrical and ferroelectric fields because of their peculiar microstructures,which provide a strong driving force throughout the whole bulk to separate photogenerated *** two orders of magnitude improvement of visible-light-driven photocatalytic H_(2) production has been realized in CdS/PbTiO_(3)/TiO_(2)compared with bare PbTiO_(3)/TiO_(2),showing the efficiency of charge separation in the *** idea of combining ferroelectrics with potential light capture semiconductor provides a paradigm to accurately design charge migration pathways,bringing a step closer to efficient solar water splitting.

摘要：The recent decade has witnessed an upsurge in the demands of intelligent and simplified Internet of Things(IoT)networks that provide ultra-low-power communication for numerous miniaturized *** the research community has paid great attention to wireless protocol designs for these networks,researchers are handicapped by the lack of an energy-efficient software-defined radio(Sdr)platform for fast implementation and experimental *** Sdrs perform well in battery-equipped systems,but fail to support miniaturized IoT devices with stringent hardware and power *** paper takes the first step toward designing an ultra-low-power Sdr that satisfies the ultra-low-power or even battery-free requirements of intelligent and simplified IoT *** achieve this goal,the core technique is the effective integration ofµW-level backscatter in our Sdr to sidestep power-hungry active radio frequency *** carefully develop a novel circuit design for efficient energy harvesting and power control,and devise a competent solution for eliminating the harmonic and mirror frequencies caused by backscatter *** evaluate the proposed Sdr using different modulation schemes,and it achieves a high data rate of 100 kb/s with power consumption less than 200µW in the active mode and as low as 10µW in the sleep *** also conduct a case study of railway inspection using our platform,achieving 1 kb/s battery-free data delivery to the monitoring unmanned aerial vehicle at a distance of 50 m in a real-world environment,and provide two case studies on smart factories and logistic distribution to explore the application of our platform.

摘要：In this work,the nickel-based powder metallurgy superalloy FGH95 was selected as experimental material,and the experimental parameters in multiple overlap laser shock processing(LSP)treatment were selected based on orthogonal experimental *** experimental data of residual stress and microhardness were measured in the same *** residual stress and microhardness laws were investigated and *** neural network(ANN)with four layers(4-N-(N-1)-2)was applied to predict the residual stress and microhardness of FGH95 subjected to multiple overlap *** experimental data were divided as training-testing sets in *** energy,overlap rate,shocked times and depth were set as inputs,while residual stress and microhardness were set as *** prediction performances with different network configuration of developed ANN models were compared and *** developed ANN model with network configuration of 4-7-6-2 showed the best predict *** predicted values showed a good agreement with the experimental *** addition,the correlation coefficients among all the parameters and the effect of LSP parameters on materials response were *** can be concluded that ANN is a useful method to predict residual stress and microhardness of material subjected to LSP when with limited experimental data.

摘要：In this study,we designed an oil-filled motor that can be used at full-ocean depths,and investigated the friction losses caused by the rotating seal and the properties of the *** direct current(dC)motor is encapsulated in an aluminum alloy housing.A rubber diaphragm is used to balance the internal and external pressures so that the motor can work on the seabed without pressure *** study the resistance caused by the rotating seal,a numerical model of the Glyd ring and the rotating shaft was *** from a rotational torque test agreed with those from numerical *** kinematic viscosity of four oils was measured at 1-25℃.Oil bath experiments in an incubator showed that the resistance from oil is highly correlated with its dynamic *** appears to be very suitable as an insulating oil for these *** working characteristics of the motor were tested in a high-pressure *** results showed that the motor needs to overcome higher oil resistance under higher pressure.A prototype of a pressure-adaptive motor was designed and applied successfully in the hadal zone at a water depth of more than 10000 m.

摘要：To study the effects of perceived control on human thermal sensation and thermal comfort in heated environments,a psychological experiment was *** total,24 subjects participated in an *** experiment consisted of two cases in which the indoor temperature was set at 18℃ with different cold radiation *** experiment lasted for 120 min and was divided into three phases,adaptation,without perceived control and perceived *** the second phase,the subjects were told in advance that the indoor temperature could not be *** the third phase,subjects were told that they could adjust the indoor temperature to meet their own thermal expectations,but the indoor temperature could not actually be *** results showed that the effect of perceived control on thermal sensation was related to the thermal *** people with strong expectations for a neutral environment,perceived control improved their thermal sensation by satisfying their thermal *** people with low thermal expectations,perceived control reduced their thermal tolerance to the environment,eventually leading to thermal *** new findings provide more supports for the importance of psychological effects and a reference for the personal control of heating temperatures.

摘要：Since a typical mammalian cell contains only 200–300 picograms of proteins and the lack of a proteome amplification strategy[1],a practical and high-throughput approach for single-cell proteomics has long been awaited.A series of methods have been explored to make single-cell proteomics *** design of nanoPOTS and OAd chip-based processes minimizes sample preparation steps and volumes to reduce sample loss[2,3].

摘要：Aqueous hybrid supercapacitors(AHSCs)offer potential safety and eco-friendliness compared with conventional electrochemical energy storage devices that use toxic and flammable organic *** can serve as the bridge between aqueous batteries and aqueous supercapacitors by combining the advantages of high energy of the battery electrode and high power as well as long lifespan of the capacitive *** the past few decades,extensive research efforts have been devoted to developing advanced materials and fascinating device architectures for ***,further development related to the compatibilities between the battery-type electrode and capacitive electrode remains stagnant mainly due to discrepancy encountered in terms of reaction kinetics and *** review focuses on the recent progress made in the field of AHSCs via elucidating the main concepts on the design of battery and capacitive electrodes and emerging *** particular,ingenious AHSCs that possess either better flexibility toward materials selection or better device functionality such as those with“dual-ion”energy storage mechanism and non-polarity feature are also *** advances and unresolved issues in multivalent ion hybrid devices(in particular,zinc-ion AHSCs)are further ***,future research directions and challenges for AHSCs are presented,which are anticipated to deliver higher energy and demonstrate greater multifunctionalities for more breakthrough technology applications.