摘要：随着人工晶体设计和制造工艺的改进以及手术技术的不断完善和提高,人工晶体手术相关并发症已逐渐减少,但仍然存在着影响手术患者预后的风险因素。通过介绍人工晶体常见的不良事件表现,并从医疗器械不良事件监测角度着重对由晶状体本身质量或材质问题导致的人工晶体不良事件及其可能原因进行分析,以期为临床正确、安全使用人工晶体提供参考。

摘要：随着白内障超声乳化技术及人工晶体植入术的发展与成熟,良好的功能性视觉已成为更多患者及临床工作者的追求。球面像差一直是传统人工晶体影响视觉功能的主要因素之一。近年来,波前像差技术的应用越来越广,在一定程度上促进了非球面人工晶体的研究与应用。非球面人工晶体的主要优势是能减少晶体的球面像差,改善白内障患者的功能性视觉。该文就非球面人工晶体的设计、分类、临床应用进行分析,并对目前所存在的问题与展望进行讨论。

摘要：自从1949年Ridley首次植入人工晶体以来,随着手术技术的提高和人工晶体设计制作的改进,人工晶体植入术得以迅速发展。特别是后房型人工晶体植入术的优越性已被公认。近年来,国内外均有不少报道。人工晶体植入术广泛开展后,新的问题接踵而来。其中,人工晶体位置异常与术后散光的问题引起了国内外眼科学者的关注。一般认为,由后房型人工晶体植入术引起的散光度数很低,较高度数的散光则与人工晶体的倾斟或脱位有关。作者曾遇一例因后房型人工晶体帧斜而导致严重散光的病例,现报告分析如下。

摘要：Purpose: To compare posterior capsule opacification (PCO) after cataract surge ry with implantation of two silicone intraocular lenses (IOLs) with different de signs. Methods: We carried out a prospective, clinical study of 116 patients ran domized to standardized phacoemulsification with implantation of CeeOnEdge (n=57 ) or SI40NB (n=59) IOLs. The follow-up period was 3 years. To evaluate PCO morp hologically, digital images were obtained and analysed using evaluation of poste rior capsule opacification computer software (EPCO). The neodymium:YAG (Nd:YAG) capsulotomy rate was recorded. Results: At 2 and 3 years, the eyes with SI40NB I OLs had significantly more PCO than those with the CeeOn Edge IOLs (p=0.00014 an d p=0.002). Nine Nd:YAG capsulotomies were performed in the SI40NB group and non e in the CeeOn Edge group. This difference was statistically significant (p=0.00 3). In some patients a regression of PCO was noticed and confirmed usingEPCO. St atistically less PCO was noted when the capsulorhexis rim was placed so that it covered all 360 degrees of the optic of the IOL. Conclusions: A clinically and s tatistically significant difference in PCO development between CeeOn Edge and SI 40NB IOLs at 2 and 3 years postoperatively was found. These findings support earlier studies indicating that a sharp edge of the opt ic is a more important factor in IOL design than IOL material in the prevention of PCO.

摘要：目的:探讨SN6AD1+3.0D非球面多焦点人工晶体植入术后的临床疗效。方法:选择2017年1月-2018年6月之间在本医院进行白内障超声乳化吸出联合人工晶体植入手术的患者81例(102眼)的资料进行回顾性分析,按照患者的手术方法分为两个组,对照组40例(51眼),观察组41例(51眼),对照组患者植入博士伦AO非球面单焦点人工晶体,观察组患者植入SN6ADA+3.0D多焦点人工晶体,比较两组患者的手术效果。结果:术后1周-3个月,两组患者的裸眼远视力和最佳矫正远视力均出现增加,但增加幅度比较差异均无统计学意义(P>0.05);两组患者的裸眼中视力,最佳矫正中视力,裸眼近视力,最佳矫正近视力均出现增加,观察组的增加幅度大于对照组,比较差异均有统计学意义(P0.05);观察组患者的中视力矫正平均屈光度[(1.52±0.23)D vs (0.73±0.12)D],近视力矫正平均屈光度[(1.74±0.24)D vs (0.86±0.21)D]均低于对照组患者,比较差异均有统计学意义(t=21.747,19.706;P<0.05),观察组患者的拟调节力[(0.38±0.13)D VS (2.66±0.42)D]和阅读脱镜率[8/40) vs (30/41)]高于对照组患者,比较差异均有统计学意义(t=-37.034,x^2=22.984,P<0.05)。结论:SN6AD1+3.0D非球面多焦点人工晶体采用独特的光学设计,可以让光线在通过晶体之后按照合理的比例分配在不同的焦点上,有效提升了手术之后患者近视力与中视力的恢复,改善生活质量,值得在临床工作中推广。

摘要：近期,北京中材人工晶体研究院有限公司(简称“人工晶体院”)采用自主设计制造的导模炉成功生长出尺寸达1000 mm×370 mm×12 mm的“米级”超大口径蓝宝石单晶,晶体表面平整、外观透明、质地均匀(见图1)。该超大尺寸蓝宝石单晶的成功研发,标志着人工晶体院在导模法蓝宝石晶体生长技术方面取得了重大突破,晶体尺寸比肩国际水平,为实现我国重大国防装备用关键核心材料的自主可控提供有力支撑。

摘要：目的观察两种不同结构设计的AcrySof丙烯酸酯折叠式人工晶体(intraocularlens,IOL)对晶状体后囊膜混浊(posteriorcapsuleopacification,PCO)的影响。方法156例(156只眼)按随机数字表法分为两组:一体式IOL组:75例(75眼),植入一体式AcrySof折叠式IOL。三体式IOL组:81例(81眼),植入三体式AcrySof折叠式IOL。术后半年散大瞳孔观察Soemmering环和PCO情况。结果术后6个月,瞳孔区PCO,一体式IOL组6只眼(8.00%),混浊多为轻微皱褶。三体式IOL组17只眼(20.99%),一体式IOL组PCO明显少于三体式IOL组,差异有显著意义(P<0.05)。结论一体式AcrySof折叠IOL独特设计的襻较使晶状体后囊膜皱褶大为减少,PCO明显下降,明显优于三体式AcrySof折叠式IOL。

摘要：白内障是全球排列第一的致盲性眼病，世界卫生组织提出到2020年消除可避免盲的第一种疾病就是白内障。目前，手术治疗是治疗白内障最有效的唯一方法，随着眼科医疗技术的飞速发展，眼科医用产品的不断更新，白内障摘除人工晶体植入术，使众多的白内障病人重见光明。为了获得术后满意的视力效果，高品质的视觉质量，患者植入的人工晶体起到至关重要的作用。为确保患者植入的人工晶体安全、度数准确，我院从2008年开始，设计使用了人工晶体专用处方，术前一天凭医生开出的专用晶体处方到中心药房领取，手术室保管的人工晶体由药剂科统一计划、采购、管理、发放，经过临床使用取得了良好的效果，现将体会报告如下。

摘要：Purpose To determine whether lens edge design or anterior capsule overlap on the intraocular lens (IOL) has greater effect on posterior capsule opacification (PCO). Design Retrospective cohort clinical study. Methods Retrospective. SETTING: Academic clinical *** POPULATION: The patient population consisted of 259 uncomplicated surgical patients (259 eyes) with no confounding comorbidity and at least 1 year of follow- up after surgical placement of a silicone or hydrophobic acrylic lens. OBSERVATION PROCEDURES: Digital retroilluminated photographs were taken to ascertain PCO, anterior capsular opacification (ACO), previous neodymium:YAG capsulotomy and degree of anterior capsule overlap on the IOL optic. MAIN OUTCOME MEASURES: PCO, ACO, YAG capsulotomy rate, and anterior capsule overlap on the IOL optic. Results One hundred forty- eight digital images (74 silicone and 74 acrylic) were measurable for both anterior capsule overlap and PCO. Complete 360 degrees of anterior capsule overlap on the IOL was associated with decreased PCO (P< .001). A significant negative correlation was found between the degree of anterior capsule overlap and PCO (P< .001). Evaluation of PCO, and YAG capsulotomy rates were similar between acrylic and silicone lenses. Minimal anterior capsule overlap may also be associated with PCO prevention. Conclusions Implanting a lens with complete anterior capsule overlap on the IOL was found to significantly reduce PCO, which advantage appeared to be greater than PCO prevention by a truncated, sharp edge IOL design.

摘要：功能晶体材料是光电功能材料的主体,经历了从天然晶体到人工晶体、从体块晶体到薄膜、从自组装到人工微结构、从大晶体到微纳米晶体化制备的发展历程。通过精确的成分设计和精细的结构控制获得具有特殊的物理、化学、力学,乃至生物学的性能,已成为微电子、光电子等现代科学技术发展的基础材料和核心技术。功能晶体材料通过晶体生长技术获得,20世纪50年代以来,以单晶硅为代表的半导体材料的发展推动了晶体生长理论研究和技术的发展。