摘要：针对药代动力学研究的需要 ,本文介绍可进行体内药物浓度在体或者连续测定的一些生物传感器。对生物传感器设计中微透析技术、纳米技术和传感器信息融合技术等新技术的应用进行了探讨 。

摘要：Objective: Amniotic fluid embolism is a potentially fatal complication of pregnancy; although several hypotheses have been formulated, the pathophysiology of this condition is not well known. An exaggerated release of bradykinin, which is activated by products of the amniotic fluid that enter the maternal circulation, could explain the symptoms that are present in amniotic fluid embolism. The objective of this study was to assess whether bradykinin is involved in amniotic fluid embolism. Study design: The plasma bradykinin-generating capacity was measured serially in a patient who experienced amniotic fluid embolism. Results: The plasma bradykinin-generating capacity was found to be very low at the time of the initial clinical manifestations, which were characterized by severe hypotension, cardiorespiratory arrest, and coagulopathy. Conclusion: This study suggests a potential role for bradykinin release in the pathophysiology of amniotic fluid embolism.