摘要：目的探讨以循征护理方法对慢性阻塞性肺疾病缓解期患者抑郁状态的改善作用。方法选择2002-03/2004-08山东省青岛疗养院呼吸康复病房慢性阻塞性肺疾病缓解期住院患者42例,随机分为循征护理组和对照组,循征护理组针对患者个性问题上网检索查询护理方法后,严格实施个性化的心理行为干预措施,并严格实施;对照组接受常规护理。两组患者分别在入院和出院时采用美国国立精神卫生研究所流行病学研究中心的抑郁量表确定护理干预前后抑郁患者及其抑郁程度的变化,采用自行设计访谈式问卷调查相关因素,即慢性阻塞性肺疾病病情5项,医药费来源4项,家属关怀4项和日常生活4项内容,按5点评分法对5个因素的担心和需求程度进行打分以评估其心理压力改善情况。结果按意向处理分析,42例患者全部进入结果分析。①循征护理组患者护理后抑郁患者比护理前明显减少(2,8,P0.05)。②循征护理组患者护理后5个因素需求程度较护理前明显降低(P<0.01),而对照组变化不明显。结论慢性阻塞性肺疾病缓解期患者抑郁状态的循征护理可减轻患者的心理压力,改善其抑郁状态,其护理效果优于传统护理方法。

摘要：The purpose of this study was to test whether modafinil is effective in alleviating the symptoms of fatigue in postpolio patients, because it has been helpful for such symptoms in other neurologic disorders. Using a double-blind, randomized, placebo-controlled cross-over design, 14 postpolio patients with moderate to severe fatigue were assigned to receive modafinil or placebo first. Piper Fatigue Scale, Epworth Sleepiness Scale, digit span, and reaction time tests were done at baseline and then at weekly intervals. The Piper Fatigue Scale scores im proved by 27 ±40%(mean ±SD) following modafinil and by 43 ±36%following pla cebo. Scores for most of the other tests did not change during the study. Therefore, we conclude that modafinil was not effective in alleviating the symptoms of fatigue in postpolio patients.