摘要：As a bone scaffold,meeting all basic requirements besides dealing with other bone-related issues-bone cancer and accelerated regeneration-is not expected from traditional scaffolds,but a newer class of scaffolds called *** a clinical point of view,being a multifunctional scaffold means reducing in healing time,direct costs-medicine,surgery,and hospitalization-and indirect costs-loss of mobility,losing job,and *** main aim of the present review is following the multifunctional bone scaffolds trend to deal with both bone regeneration and cancer *** consideration is given to different fabrication techniques which have been applied to yield these materials spanning from traditional to modern ***,the hierarchical structure of bone plus bone cancers and available medicines to them are introduced to familiarize the potential reader of review with the pluri-disciplinary essence of the ***,a brief discussion relating to the future trend of these materials is provided.