摘要：In Turkey, from the second half of the nineteenth century, the shaping of an art of painting on the basis of Western understanding was realized with state support. From this period, certain art movements were seen as the means of modernization and Westernization. Therefore, impressionism, cubism, realism, and classicism were supported by the state as a formal artistic understanding. This attitude continued until the 1940s and artists painted certain subject matters on the basis of these art movements. The main theme and subject matters were the presentations of an idealized society such as palace＇s life, attractive women in Western appearance, happy peasants, war heroes, and beautiful views from the country. In the early 1940s, significant breakup began to take place in point of the theme and the subject matter of art. Social realism began to take shape for the first time in art in Turkey. The artists of Yeniler Grubu （Newcomers Group） focused on social phenomena related disadvantaged social groups rather than an idealized society. Some artists among the 1950 generation, especially Nedim Gunsur, Nuri iyem, and Miimtaz Yener, focused on migration and social problems that occurred correspondingly in the 1960s and 1970s. This paper aims to investigate how these artists depicted and interpreted the migration and its consequences.

摘要：This paper presents a new depth migration method, adaptive spatial-division split-step Fourier （ASDSSF） migration. In this method we introduce the idea of a stratified phase shift migration into the split-step Fourier （SSF） migration to make an accurate and efficient wave field image when sharp discontinuities appear in the velocity field. In principle, the ASDSSF migration is a multi-reference slowness （reciprocal of velocity） （MRS） migration. Compared to previous MRS migration methods, this method uses fewer reference slowness values without accuracy loss. The reference slowness is determined in this paper according to an error-control parameter of the perturbation term in the SSF operator and the variation of the complet velocity field. The velocity corresponded to reference slowness can define a spatial division. Each division can also be divided into several discontinuous spatial subdivisions to effectively reduce the number of reference slowness values needed. The choice of reference slowness, including the number of reference slowness values needed and how to construct the spatial divisions, is adaptive and reasonable at each extrapolation step （depth step）. A simple and economical smoothing filter in the wave number-frequency domain is designed to avoid artifacts in the wave field extrapolation due to the presence of sharp discontinuities in the velocity field. For comparable conditions the present approach to migration is expected to be computationally more efficient and accurate than other MRS migration methods. The performance of the method is demonstrated on a simple 2D prestack model and the prestack SEG/EAEG salt dataset.

摘要：为构成高性能的数据库,磁盘阵列的活用是很有必要的。其中尤为重要的是实现磁盘阵列之间负载的均衡。为此,设计了网络磁盘结构系统,该系统在磁盘阵列高负载的情况下也能够进行动态的负载均衡,并且具有优良的耐故障性。对于网络磁盘结构构成要素中的Local migration Manager(LMM)进行了设计。列举出了LMM连接的Main Bus上传送的信息,定义了信息形式,信息的传送与Bus的宽度相符呈分割进行;在LMM的设计方法中定义了LMM的内部数据结构;在此基础上,制作了LMM的算法。

摘要：Modern high-level programming languages often contain constructs whose semantics are non-trivial. In practice however, software developers generally restrict the use of such constructs to settings in which their semantics is simple (programmers use language constructs in ways they understand and can reason about). As a result, when developing tools for analyzing and manipulating software, a disproportionate amount of effort ends up being spent developing capabilities needed to analyze constructs in settings that are infrequently used. This paper takes the position that such distinctions between theory and practice are an important measure of the analyzability of a language.

摘要：Focal adhesion kinase(FAK)is an intracellular tyrosine kinase that plays a critical role in the occurrence,development,and metastasis of cancer through both its kinase-dependent catalytic functions and kinase-independent scaffolding *** kinase inhibitors target only its catalytic activity,leaving the scaffolding functions ***,proteolysis targeting chimeras(PROTACs)offers a promising approach by degrading the entire FAK protein,thereby inhibiting both functions *** this study,we designed and synthesized novel PROTAC degraders,utilizing a defactinib derivative(compound 12)as the FAK ligand and a lenalidomide analog as the E3 ligase *** structures of these compounds were confirmed through^(1)H NMR,^(13)C NMR,and high-resolution mass spectrometry(HRMS).Among the synthesized compounds,the optimized compound 16b exhibited potent degradation activity against FAK protein in A549 cells,with a DC_(50)of 6.16±1.13 n M,significantly inhibiting the proliferation and colony formation of these *** to defactinib,16b showed enhanced inhibition of A549 cell migration and ***,our research demonstrated that the rapid and effective FAK degradation induced by 16b was mediated by a CRBN-dependent proteasome mechanism.

摘要：A unique porcine extracellular matrix (ECM) derived injectable tissue construct with 100 nm or 20 nm gold nanoparticles (AuNP) was developed for musculoskeletal tissue engineering applications. ECM has been shown to encourage cellularity and tissue remodeling due to its release of growth factors while AuNP have been shown to reduce reactive oxygen species (ROS) levels. Injectable tissue constructs were created by homogenizing decellularized porcine diaphragm tendon conjugated with 100 nm or 20 nm AuNP at 1x, 4x, and 8x concentrations. Extrusion force testing demonstrated that homogenized tissue constructs were injectable at an appropriate cannula size and force. L-929 murine fibroblasts were used to measure cell viability, cell proliferation, intracellular ROS levels, and cell migration in response to constructs. Enhanced cell viability and proliferation are observed on 1 × 20 nm AuNP constructs. ROS assays demonstrate reduced cellular ROS concentrations from all 20 nm AuNP constructs and from 8 × 100 nm AuNP constructs compared with constructs without nanoparticles. Cellular migration is higher towards 4 × 20 nm AuNP constructs compared with constructs without nanoparticles. Results support the potential use of a porcine ECM derived injectable tissue construct with AuNP as an injectable tissue construct to reduce inflammation and to promote tissue remodeling in musculoskeletal tissue engineering applications.

摘要：ABS喉管被选用於加压供水系统中,安装後数月内相继出现渗漏及裂缝.应力分析显示室外温差及安装时的工差并不会导致ABS喉管大量断裂失效.FTIR光谱分析指出ABS存有外来污染物,经仔细调查後发现ABS的污染源乃ABS喉管与金属托座之间的塑胶软垫.塑胶软垫含有大量的phthalate,通过phthalate migration渗透至ABS材料中,导致ABS的强度大幅降低了90%以上.变弱了的ABS喉管部分因而再也不能承受原设计负载,并且最终破裂和渗漏.因此,必须确保含phthlate的物质不被应用於ABS结构中.