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检索条件"主题词=Photodynamic therapy"
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Light/pH dual controlled drug release"nanocontainer"alleviates tumor hypoxia for synergistic enhanced chemotherapy,photodynamic therapy and chemodynamic therapy
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《Bio-Design and Manufacturing》2024年 第6期7卷 955-971页
作者:Shihe Liu Xin Zhang Zhimin Bai Yibo Yang Jia Zhang Kun Li Zhiwei Liu Ming Shi Lixin Dong Jidong Wang Jian LiHebei Key Laboratory of Applied ChemistryHebei Key Laboratory of NanobiotechnologyHebei Key Laboratory of Heavy Metal Deep-Remediation in Water and Resource ReuseYanshan UniversityQinhuangdao 066004China Qinhuangdao Biopha Biotechnology Co.Ltd.Qinhuangdao 066000China The First Hospital of QinhuangdaoQinhuangdao 066000China Department of Biological EngineeringCollege of Environment and Chemical EngineeringYanshan UniversityQinhuangdao 066004China 
photodynamic therapy(PDT)has significant advantages in treating primary ***,the hypoxic tumor microenvironment hinders the generation of sufficient reactive oxygen species during PDT to effectively kill tumor cells,fu...
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In vitro 3D malignant melanoma model for the evaluation of hypericin-loaded oil-in-water microemulsion in photodynamic therapy
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《Bio-Design and Manufacturing》2022年 第4期5卷 660-673页
作者:Hui LMa Wanlu Li Mian Wang Laudemir C.Varanda Janice R.Perussi Y.Shrike Zhang Emanuel CarrilhoInstituto de Química de São CarlosUniversidade de São PauloUSPAv.Trabalhador São-carlenseSão CarlosSP 13566-590Brazil Instituto Nacional de Ciência e Tecnologia de BioanalíticaINCTBioCampinasSP 13083-970Brazil Division of Engineering in MedicineDepartment of MedicineBrigham and Women’s HospitalHarvard Medical SchoolCambridgeMA 02139USA 
Advances in biomimetic three-dimensional(3D) melanoma models have brought new prospects of drug screening and disease modeling, since their physiological relevancy for recapitulating in vivo tumor architectures is mor...
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Gold nanorod-photosensitizer conjugate with extracellular pH-driven tumor targeting ability for photothermal/photodynamic therapy
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《Nano Research》2014年 第9期7卷 1291-1301页
作者:Nannan Wang Zilong Zhao Yifan Lv Huanhuan Fan Huarong Bai Hongmin Meng Yuqian Long Ting Fu Xiaobing Zhang Weihong TanMolecular Science and Biomedicine Laboratory State Key Laboratory for Chemo/Bio-Sensing and Chemometrics College of Chemistry and Chemical Engineering College of Biology and Collaborative Research Center of Molecular Engineering for Theranostics Hunan University Changsha 410082 China Department of Chemistry and Department of Physiology and Functional Genomics Center for Research at Bio/nano Interface Shands Cancer Center UF Genetics Institute and McKnight Brain Institute University of Florida Gainesville Florida 32611-7200 USA 
Chlorin e6-pHLIPss-AuNRs, a gold nanorod-photosensitizer conjugate containing a pH (low) insertion peptide (pHLIP) with a disulfide bond which imparts extracellular pH (pHe)-driven tumor targeting ability, has b...
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Construction of Type I Aggregation-Induced Emission Photosensitizers for photodynamic therapy via Photoinduced Electron Transfer Mechanism
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《有机化学》2024年 第8期44卷 2530-2537页
作者:Jia Hanyu Yu Yuewen Feng Guangxue Tang Ben ZhongGuangdong Provincial Key Laboratory of Luminescence from Molecular AggregatesState Key Laboratory of Luminescent Materials and DevicesSchool of Materials Science and EngineeringSouth China University of TechnologyGuangzhou 510640 Shenzhen Institute of Aggregate Science and TechnologySchool of Science and EngineeringThe Chinese University of Hong KongShenzhenGuangdong 518172 
photodynamic therapy(PDT)as a non-invasive anticancer modality has received increasing attention due to its advantages of noninvasiveness,high temporospatial selectivity,simple and controllable operation,*** mainly re...
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Programmable starving-photodynamic synergistic cancer therapy
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《Science China Materials》2020年 第4期63卷 611-619页
作者:Leli Zeng Kai Huang Yilin Wan Jing Zhang Xikuang Yao Chao Jiang Jing Lin Peng HuangMarshall Laboratory of Biomedical EngineeringInternational Cancer CenterLaboratory of Evolutionary Theranostics(LET)School of Biomedical EngineeringShenzhen University Health Science CenterShenzhen 518060China Research CentreThe Seventh Affiliated HospitalSun Yat-sen UniversityShenzhen 518107China 
Synergistic therapy combines multiple therapeutic approaches in one shot,thus could significantly amplify the therapeutic ***,how to design the desirable combination to maximize the synergistic effect is still a big c...
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A pH-responsive zinc(Ⅱ) metalated porphyrin for enhanced photodynamic/photothermal combined cancer therapy
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《Science China Materials》2019年 第8期62卷 1199-1209页
作者:Pingpine Liang Hao Tang Rui Gu Lei Xue Dapeng Chen Wenjun Wang Zhou Yang Weili Si Xiaochen DongKey Laboratory of Flexible Electronics (KLOFE)& Institute of Advanced Materials (LAM) Nanjing Tech University (NanjingTech) Nanjing 211800 China School of Physical Science and Information Technology Liaocheng University Liaocheng 252059 China Department of Pharmaceutical Preparation Jinling Hospital Nanjing 210002 China Beijing Key Laboratory of Function Materials for Molecule & Structure Construction School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China 
The acidic tumor microenvironment is triggered by glycolysis in hypoxic condition, which can motivate the pHresponsive system to build certain triggers for efficiently tumor-targeted phototherapy. Additionally, the me...
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Carrier-adjuvanted immunostimulator to boost photodynamicimmunotherapy by downregulating PD-L1 and impairing ATP hydrolysis
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《Science China Materials》2025年 第2期68卷 626-639页
作者:Yi Cen Ying Chen Hua Cai Xinxuan Li Xiayun Chen Qianqian Liu Baixue Yu Yibin Liu Tao Wang Shiying LiThe Fifth Affiliated HospitalGuangdong Provincial Key Laboratory of Molecular Target&Clinical Pharmacologythe NMPA and State Key Laboratory of Respiratory Diseasethe School of Pharmaceutical SciencesGuangzhou Medical UniversityGuangzhou 511436China Graduate SchoolGuangzhou University of Chinese MedicineGuangzhou 510006China Department of Pulmonary and Critical Care MedicineZhujiang HospitalSouthern Medical UniversityGuangzhou 510280China 
Immune evasion behavior and immunosuppressive characteristics of tumor extensively impedethe immune initiation effect of therapy triggered immunogeniccell death (ICD). In this work, a carrier-adjuvantedimmunostimulato...
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Photosynthetic biomaterials: applications of photosynthesis in algae as oxygenerator in biomedical therapies
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《Bio-Design and Manufacturing》2021年 第3期4卷 596-611页
作者:Yong Wang Yanan Xue Tao Zhang Qingqing Fang Mingyuan Jin Xiaofeng Wang Zhengcai Wang Yanyan Hu Wanyi Zhao Dong Lou Wei-Qiang TanDepartment of Plastic SurgerySir Run Run Shaw HospitalZhejiang University School of Medicine3 East Qingchun RoadHangzhou 310016China Department of Plastic SurgeryThe Fourth Affiliated HospitalZhejiang University School of MedicineN1 Shangcheng RoadYiwu 322000China 
For most organisms,molecular oxygen is indispensable for normal physiological metabolism;in humans,prolonged hypoxia in tissues can induce many diseases,exemplified by cardiovascular disease,chronic wounds,and tissue ...
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PEGylated carbon dot/MnO_2 nanohybrid: a new pH/H_2O_2-driven, turn-on cancer nanotheranostics
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《Science China Materials》2018年 第10期61卷 1325-1338页
作者:Shiqing Chen Qingyan Jia Xiuli Zheng Yongmei Wen Weimin Liu Hongyan Zhang Jiechao Ge Pengfei WangKey Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and DevicesTechnical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China School of Future TechnologyUniversity of Chinese Academy of SciencesBeijing 100049China 
The effect of tumor-targeted photodynamic therapy(PDT) was improved by designing nanotheranostics to promote oxygenation in a tumor microenvironment(TME)wherein hypoxia, acidosis, and the elevated levels of H2O2 a...
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