摘要：A series of carbamate-containing sialyltransferase inhibitors were designed and synthesized to simulate phosphate-linked *** inhibitory activities were assayed against recombinant human ST3Gal I and ST6Gal I by using the Schmidt’s HPLC-based *** synthetic compound 15 g showed moderate inhibitory *** findings implied that carbamate might serve as a bioisosteric replacement for a phosphate group in sialyltransferase inhibitor design to improve the membrane permeability.