摘要：Main observation and conclusion A full account of the total synthesis of(-)-pallambins A-D(1-6)is *** strategy was devised by simulating their biosynthetic *** left-part bicyclo[3.2.1]octane system of pallambins C and D was efficiently constructed via a palladium-catalyzed oxidative cyclization.

摘要：Anisotanols A—D(1-4),four new compounds possessing an unprecedented sesquiterpenoid skeleton with a congested tricyclic 6/3/5 ring system,were obtained from Anisodus *** structures were elucidated by comprehensive spectroscopic techniques,and the absolute configurations were confirmed via ECD calculations and single-crystal X-ray diffractions.A putative biosynthetic pathway for these compounds was *** evaluation disclosed that compound 3 showed anti-angiogenic activity by inhibiting the viability,migration,and tube formation in HUVECs.