摘要：At some point in the natural course of colorectal cancer up to 50% of patients will develop metastasis to the liver and it is one of the most critical effects for patient prognosis. The incidence of synchronous liver metastasis has been detected at around 20% - 25%, but the optimal timing of surgical resection remains controversial. Neoadjuvant chemotherapy has also been found to be beneficial not only for initially unresectable but also resectable synchronous metastases. Then, traditional surgical strategies of hepatic resection in accordance with past chemotherapeutic regimens have been used decreasingly over the past several years. This review will primarily discuss treatments in association with the recent developed chemotherapeutic regimens and surgical procedure from the clinical data and the concept for epithetlial-mesenchymal transition, which has recently been studied to elucidate mechanisms of the liver metastatic process.

摘要：崔宪基1962年出生于吉林省1985年毕业于延边大学美术系1994年中央美术学院七届油画研修班2004年毕业于韩国弘益大学美术学硕士现生活、工作在北京一切意义皆始于符号。无论是有意或是无意,意义都是沿着无知之路通向智慧之都。我们可能会创造一个符号,或者留下一个符号,然后再判断其价值。我们可能不久以后还会再加上一个符号,作为对第一个符号的补充。接下来、我们便会得到一幅图片,或者一门语言,或两者兼得。但是无论我们得到了什么,都会使我们的现实观变得更为复杂。难道真的是必要的吗？答案是当然。