摘要：This paper introduces the structural design optimization of a tall building with reinforced concrete frame-core shear walls in Guangzhou *** decrease the construction cost,wide flat beam with 400 mm ×650 mm rectangular cross-section are adopted for main *** measures are used to decrease noncoincident centers of mass and *** subway tunnels cross the building underground,inclined columns,the second and third floor underground together function as the underpinning *** from traditional transform beam,the proposed underpinning structures show good performance without using large dimensional bending *** attentions should be paid to the beams connecting with the inclined column in the underpinning structures,and these beams show large tensile or compressive *** observations after completion construction indicate that the building as well as the proposed design measures work well.