摘要：At present,there are few programs that can be used directly for ADS sub-critical core design and burnup problem mainly because most programs cannot simultaneously calculate proton spallation processes and transport problems of high-energy *** we use the COUPLE3.0 to accomplish all the calculation task in this *** COUPLE3.0 program is a three-dimensional transport-burnup simulation program developed by Institute of Modern Physics,Chinese Academy of *** transport calculation part of COUPLE3.0 program is Monte Carlo code MCNPX2.7 and the burnup calculation is performed by *** of COUPLE3.0 program has been verified by a lot of *** COUPLE3.0 program has four function modules:neutron irradiation burnup calculation,proton irradiation calculation,critical calculation and the data post-processing *** these function modules,COUPLE3.0 program can solve the neutron problem of ADS system.