摘要：Consider a semiparametric regression model with linear time series errors Y_k= x′ _kβ + g(t_k) + ε_k, 1 ≤ k ≤ n, where Y_k's are responses, x_k =(x_(k1),x_(k2),&#183;&#183;&#183;,x_(kp))′ and t_k ∈ T is contained in R are fixed design points, β =(β_1,β_2,&#183;&#183;&#183;,β_p)′ is an unknown parameter vector, g(&#183;) is an unknown bounded real-valuedfunction defined on a compact subset T of the real line R, and ε_k is a linear process given byε_k = ∑ from j=0 to ∞ of ψ_je_(k-j), ψ_0=1, where ∑ from j=0 to ∞ of |ψ_j| < ∞, and e_j,j=0, +-1, +-2,&#183;&#183;&#183;, ard i.i.d. random variables. In this paper we establish the asymptoticnormality of the least squares estimator of β, a smooth estimator of g(&#183;), and estimators of theautocovariance and autocorrelation functions of the linear process ε_k.

摘要：A multi-world mechanism is developed for modeling evolutionary design process from conceptual design to detailed design. In this mechanism, the evolutionary design database is represented by a sequence of worlds corresponding to the design descriptions at different design stages. In each world, only the differences with its ancestor world are recorded. When the design descriptions in one world are changed, these changes are then propagated to its descendant worlds automatically. Case study is conducted to show the effectiveness of this evolutionary design database model.

摘要：Ceramic-reinforced metal matrix composites(MMCs)display beneficial properties owing to their combination of ceramic and metal ***,the properties are highly dependent on the reinforcing phase composition,volume fraction and *** fiber or network reinforcement morphologies are difficult and expensive to manufacture,and the often-used discontinuous particle or whisker reinforcement morphologies result in less effective ***,we demonstrate the formation of a co-continuous ceramic-reinforced metal matrix composite using solid-state *** jet additive manufacturing(BJAM)was used to print a nickel superalloy part followed by post-processing via reactive sintering to form a continuous carbide reinforcing phase at the particle *** kinetics of reinforcement formation are investigated in order to develop a relationship between reactive sintering time,temperature and powder composition on the reinforcing phase thickness and volume *** evaluate performance,the wear resistance of the reinforced BJAM alloy 625 MMC was compared to unreinforced BJAM alloy 625,demonstrating a 64%decrease in the specific wear rate under abrasive wear conditions.

摘要：Here, we report a study of ion transport across graphene oxide （GO） membranes of various thicknesses, made by vacuum filtration of GO aqueous solutions. The diffusive transport rates of two charge-equivalent ruthenium complex ions Ru（bpy）3^2＋ and Ru（phen）32% with a sub-angstrom size difference, are distinguishable through GO membranes and their ratio can be a unique tool for probing the transport-relevant pore structures. Pore and slit-dominant hindered diffusion models are presented and correlated to experimental results. Our analysis suggests that ion transport is mostly facilitated by large pores （larger than 1.75 nm in diameter） in the relatively thin GO membranes, while slits formed by GO stacking （less than 1.42 nm in width） become dominant only in thick membranes. By grafting PEG molecules to the lateral plane of GO sheets, membranes with enlarged interlayer spacing were engineered, which showed drastically increased ion transport rates and lower distinction among the two ruthenium complex ions, consistent with the prediction by the slit-dominant steric hindered diffusion model.

摘要：Functional performance variations of products and systems are often used to measure the qualities of products and systems considering the changes in the design parameter values caused by uncertainties.A robust design approach has been developed in this research to minimize the functional performance variations considering the design parameter uncertainties by identifying the boundaries of the functional performance variations through *** this work,a mathematical model is developed to describe the relationships among functional performance,design configurations and parameters,and design parameter uncertainties.A multi-level optimization model is established to identify:(1)The optimal design configuration,(2)the optimal values of design parameters,and(3)the boundaries of functional performance *** analysis considering the impact of parameter uncertainties on functional performance variation boundaries has also been conducted.A case study on the design of a truss system has been *** study results show that the sensitivities of functional performance variation boundaries to the design parameter uncertainties can be reduced significantly using the new robust design approach.

摘要：对于日益城市化的中国人来说,淘宝等网站和手机应用加速完成了各种社会交易无论是设置虚拟恋人的叫醒电话,或是凌晨3点寻找平面设计师来设计公司标志。正是在这样的社会背景下,我们方能理解王兵影片中不妥协的力量。这位工作生活在北京的导演在全然不同的时间性、社会现实和政治意识之间游刃穿梭。沃迪斯当代艺术研究所展览标题中展览标题中的＂肖像＂是指王兵的三部影片,这不是一次由片头至片尾的电影放映,而是用展厅空间呈现的展览,尖锐地描绘了被当代中国的宏大叙事遗忘了的个体命运。这些影片绝不是那种能在手机上随意观看的＂秒拍＂视频。

摘要：novel technologies in consideration of industrial sustainability(IS)are in urgent need to satisfy the increasing demands from the *** realizes the production of materials while maintaining environmental and resource *** chemical materials used in CO2 capture and storage(CCS)technologies play a significant role in the disposal of greenhouse gas emissions coming from large stationary fossil-fired power plants,which breaks the principle of IS and brings severe environmental *** study aims at providing a detailed review of first-principles modeling(density functional theory,DFT)of materials in CO2 capture *** analysis provides insight into the atomic properties of the studied systems and builds an efficient guidance of the future design of the materials used in CO2 capture *** materials including oxygen carriers,metal organic frameworks,membranes,zeolites,ionic liquids and some other promising candidates are *** computational studies bring the outcomes of the adsorption behaviors,structural characteristics and accurate force fields of the studied materials in short turn-around times at low *** review can stimulate the design of novel materials with specific target of CO2 capture and promote the industrial sustainability of fossil fuel combustion technologies.

摘要：Fungi are nature’s recyclers,allowing for ecological nutrient cycling and,in turn,the continuation of life on *** fungi inhabit the human microbiome where they can provide health benefits,while others are opportunistic pathogens that can cause ***,members of the fungal kingdom,have been domesticated by humans for the production of beer,bread,and,recently,medicine and ***,the great untapped potential exists within the diverse fungal ***,many yeasts are intractable,preventing their use in biotechnology or in the development of novel treatments for pathogenic ***,as a first step for the domestication of new fungi,an efficient DnA delivery method needs to be ***,we report the creation of superior conjugative plasmids and demonstrate their transfer via conjugation from bacteria to 7 diverse yeast species including the emerging pathogen Candida *** create our superior plasmids,derivatives of the 57 kb conjugative plasmid pTA-Mob 2.0 were built using designed gene deletions and insertions,as well as some unintentional ***,a cluster mutation in the promoter of the conjugative gene traJ had the most significant effect on improving conjugation to *** addition,we created Golden Gate assembly-compatible plasmid derivatives that allow for the generation of custom plasmids to enable the rapid insertion of designer genetic ***,we demonstrated that designer conjugative plasmids harboring engineered restriction endonucleases can be used as a novel antifungal agent,with important applications for the development of next-generation antifungal therapeutics.

摘要：综合考虑蒸汽吞吐过程中地层膨胀和再压实诱发的孔隙变形和渗透率变化,改进了现有地质力学模型并与渗流方程进行热力学耦合,形成渗流-地质力学耦合模型,将耦合模型与响应面法和拉丁超立方体设计相结合,进行敏感性分析和不确定性评价,量化地层膨胀-再压实参数对蒸汽吞吐效果的影响。研究表明,改进的渗流-地质力学耦合模型可以更准确地实现注汽压力、注汽量及油水产量的历史拟合;线性模型和二次模型中,再压实压力的升高对注汽量和产水量的增加影响最明显,压缩系数、再压实压力与注汽量和油水产量正相关,膨胀压力与注汽量和油水产量负相关;线性模型中,膨胀压力对累计产油量的影响最明显且负相关,压缩系数、再压实压力与产油量正相关;二次模型中,再压实压力对累计油水产量和注汽量影响最明显且正相关;膨胀压力、再压实压力与海绵状岩石压缩系数之间的交互作用对累计油水产量和累计注汽量均具有负面影响。

摘要：For most organisms,molecular oxygen is indispensable for normal physiological metabolism;in humans,prolonged hypoxia in tissues can induce many diseases,exemplified by cardiovascular disease,chronic wounds,and tissue ***,the oxygen in our environment is vital for *** a main source of oxygen in the natural world that transforms light energy into chemical energy and oxygen,photosynthesis has been widely studied in scientific research and used in production of food,fuel,and *** recent years,photosynthesis has become more closely involved in biomedicine and has been widely used in photodynamic therapy,tissue regeneration,transplantation,and in treatment of specific *** review summarizes innovative applications of photosynthesis in biomedical research and highlights the theory and implications of clinical treatment for specific diseases.