摘要：Subcellular location is one of the key biological characteristics of proteins. Position-specific profiles （PSP） have been introduced as important characteristics of proteins in this article. In this study, to obtain position-specific profiles, the Position Specific lterative-Basic Local Alignment Search Tool （PSI-BLAST） has been used to search for protein sequences in a database. Position-specific scoring matrices are extracted from the profiles as one class of characteristics. Four-part amino acid compositions and lst-7th order dipeptide compositions have also been calculated as the other two classes of characteristics. Therefore, twelve characteristic vectors are extracted from each of the protein sequences. Next, the characteristic vectors are weighed by a simple weighing function and inputted into a BP neural network predictor named PSP-Weighted Neural Network （PSP-WNN）. The Levenberg-Marquardt algorithm is employed to adjust the weight matrices and thresholds during the network training instead of the error back propagation algorithm. With a jackknife test on the RH2427 dataset, PSP-WNN has achieved a higher overall prediction accuracy of 88.4% rather than the prediction results by the general BP neural network, Markov model, and fuzzy k-nearest neighbors algorithm on this dataset. In addition, the prediction performance of PSP-WNN has been evaluated with a five-fold cross validation test on the PK7579 dataset and the prediction results have been consistently better than those of the previous method on the basis of several support vector machines, using compositions of both amino acids and amino acid pairs. These results indicate that PSP-WNN is a powerful tool for subcellular localization prediction. At the end of the article, influences on prediction accuracy using different weighting proportions among three characteristic vector categories have been discussed. An appropriate proportion is considered by increasing the prediction accuracy.

摘要：论文设计实现了一种用于训练高炮操作手的虚拟高炮仿真训练系统。它既可训练炮手的操作能力,又可对炮手训练效果进行评估,还能挂接在DIS仿真系统中,作为大型作战仿真训练系统的一个子模块,进行合成训练,因而能显著提高高炮操作手的训练效果。

摘要：针对可重复使用飞行器(RLV)进场着陆拉平段的纵向控制问题,提出了反馈控制与前馈控制相结合的复合控制策略。设计反馈控制律参数,在此基础上基于时间加权高度跟踪误差/误差变化率平方积分指标优化设计前馈控制律参数。按输入补偿的前馈控制在不影响系统稳定性的前提下,提高了RLV对拉平着陆轨迹的跟踪精度,减小了RLV的接地散布。提出了基于积分器初值的控制律平滑切换方法,实现了RLV起落架释放前后不同控制律之间的平滑切换。仿真验证了拉平纵向复合控制和拉平过程中不同控制律之间平滑切换方法的有效性。

摘要：现有蛋白质亚细胞定位方法针对水溶性蛋白质而设计,对跨膜蛋白并不适用。而专门的跨膜拓扑预测器,又不是为亚细胞定位而设计的。文章改进了跨膜拓扑预测器TMPHMMLoc的模型结构,设计了一个新的二阶隐马尔可夫模型;采用推广到二阶模型的Baum-Welch算法估计模型参数,并把将各个亚细胞位置建立的模型整合为一个预测器。数据集上测试结果表明,此方法性能显著优于针对可溶性蛋白设计的支持向量机方法和模糊k最邻近方法,也优于TMPHMMLoc中提出的隐马尔可夫模型方法,是一个有效的跨膜蛋白亚细胞定位预测方法。

摘要：应用能量流和层次化分析方法,分析了多能量域工程系统的建模策略,采用基于SIDOPS语言的键合图开发工具,结合面向对象技术,对海洋资源开采波浪补偿装置进行了多能量域集成分析,提出了复杂系统层次化建模方法,为虚拟样机集成设计提供了前期基础研究。

摘要：随着陆、海、空等交通方式的快速发展,以地面无人系统(UGS)、无人机系统(UAV)、海上无人系统(UMS)为代表的无人系统受到了广泛关注,但是无人系统所处外部环境复杂多变,其设计开发充满挑战。针对这一情况,以中科院王飞跃研究员提出的平行系统理论为指导,提出了平行无人系统解决方案。本文首先讨论了无人系统的概念,并对无人系统的自主性和复杂性进行了分析;然后根据平行理论,提出了平行无人系统的概念和框架,并对平行无人系统的建模、平行学习、平行规划、平行控制等关键技术进行了研究;最后,以平行无人系统框架为基础,设计了平行驾驶验证平台和平行机器人验证平台,通过实验证明了平行无人系统框架可提高无人车及机器人在复杂场景下的安全性和稳定性。