摘要：due to the current trend towards lightweight design in automotive industry,hollow stepped gear shafts for automobile and its radial forging process are widely *** coupled finite element thermo-mechanical model,radial forging process of a hollow stepped gear shaft for automobile was *** optimal combination of three process parameters including initial temperature,rotation rate and radial reduction was also selected using orthogonal design *** examine the strain inhomogeneity of the forging workpiece,the strain inhomogeneity factor was *** results reveal that the maximum effective strain and the minimum effective strain appeared in the outermost and innermost zones of different cross sections for the hollow stepped gear shaft,*** forging parameters are determined as a combination of initial temperature of 780°C,rotation rate of 21°/stroke and radial reduction of 3 mm.

摘要：The key to managing fracture is to achieve stable internal fixation,and currently,biologically and mechanically appropriate internal fixation devices are urgently *** excellent biocompatibility and corrosion resistance,titanium–niobium alloys have the potential to become a new generation of internal fixation materials for ***,the role and mechanism of titanium–niobium alloys on promoting fracture healing are still ***,in this study,we systematically evaluated the bone-enabling properties of Ti45Nb via in vivo and in vitro *** vitro,we found that Ti45Nb has an excellent ability to promote MC3T3-E1 cell adhesion and proliferation without obvious *** phosphatase(ALP)activity and alizarin red staining and semiquantitative analysis showed that Ti45Nb enhanced the osteogenic differentiation of MC3T3-E1 cells compared to the Ti6Al4V *** the polymerase chain reaction experiment,the expression of osteogenic genes in the Ti45Nb group,such as ALP,osteopontin(OPN),osteocalcin(OCN),type 1 collagen(Col-1)and runt-related transcription factor-2(Runx2),was significantly higher than that in the control ***,in the western blot experiment,the expression of osteogenic-related proteins in the Ti45Nb group was significantly increased,and the expression of PI3K–Akt-related proteins was also higher,which indicated that Ti45Nb might promote fracture healing by activating the PI3K–Akt signaling *** vivo,we found that Ti45Nb implants accelerated fracture healing compared to Ti6Al4V,and the biosafety of Ti45Nb was confirmed by histological ***,immunohistochemical staining confirmed that Ti45Nb may promote osteogenesis by upregulating the PI3K/Akt signaling *** study demonstrated that Ti45Nb exerts an excellent ability to promote fracture healing as well as enhance osteoblast differentiation by activating the PI3K/Akt signaling pathway,and its good biosafety has been confirmed

摘要：“2010 3d中国高峰会展”于7月16日、17日在朝阳规划艺术馆盛大举行。中国电影家协会分党组书记，兼常务副主席康健民、国家广电总局制片技术处处长丁立等有关部门和专业协会领导参与。据广电总局透露，加强3d影视研发和3d影院建设已经纳入了广播电视“十二五”重点考虑的项目。而论坛本身也吸引了上千观众到场，普通观众在现场可以通过提问等方式参与讨论。呈现出市场对3d娱乐产业关注的视角。