摘要：Biodegradable Mg-Zn alloy was synthesized using mechanical alloying where a statistical model was developed using fractional factorial design to predict elastic modulus and mass loss of the bulk *** effects of mechanical alloying parameters(i.e.,milling time,milling speed,ball-to-powder mass ratio and Zn content)and their interactions were investigated involving 4 numerical factors with 2 replicates,thus 16 runs of two-level fractional factorial *** of analysis of variance(ANOVA),regression analysis and R2 test indicated good accuracy of the *** statistical model determined that the elastic modulus of biodegradable Mg-Zn alloy was between 40.18 and 47.88 GPa,which was improved and resembled that of natural bone(30-57 GPa).Corrosion resistance(mass loss of pure Mg,33.74 mg)was enhanced with addition of 3%-10%Zn(between 9.32 and 15.38 mg).The most significant independent variable was Zn content,and only the interaction of milling time and ball-to-powder mass ratio was significant as P-value was less than ***,mechanical properties(represented by elastic modulus)and corrosion resistance(represented by mass loss)of biodegradable Mg-Zn alloy can be statistically predicted according to the developed models.