摘要：Anisotanols A—D(1-4),four new co.pounds possessing an unprecedented sesquiterpenoid skeleton with a co.gested tricyclic 6/3/5 ring system,were obtained from Anisodus *** structures were elucidated by co.prehensive spectrosco.ic techniques,and the absolute co.figurations were co.firmed via ECD calculations and single-crystal X-ray diffractions.A putative biosynthetic pathway for these co.pounds was *** evaluation disclosed that co.pound 3 showed anti-angiogenic activity by inhibiting the viability,migration,and tube formation in HUVECs.