摘要：Titanium(Ti)and titanium alloys have become widely used as biomedical materials in orthopedics because of their good machinability,corrosion resistance,low elastic modulus and excellent ***,when Ti-based implants are used for bone repair and replacement,they are easy to cause bacteria adhesion and aggregation,which leads to postoperative *** addition,Ti and its alloys,as bio-inert materials,cannot induce desirable tissue responses such as osseointegration after implantation,which will eventually lead to implant *** bacterial infection and lack of osseointegration directly lead to the failure of implantation surgery and are not conductive to the long-term service of titanium-based ***,researchers have made many attempts to focus on the surface modification of multifunctional Ti-based implants to endow them with both antibacterial activity and simultaneous osteoinductive *** this review,we primarily highlighted the recent progresses in the surface design of Ti implants with both antimicrobial and osteoinductive properties for orthopedic ***,the challenges for treating implant-associated infections were briefly introduced such as the emergence of antibiotic resistance,the formation of biofilms,and the construction of cell-selective *** of the essential fundamentals were concisely introduced to address these emerging ***,we intended to elaborate the potential strategies of multifunctional surface design to endow good osseointegration for antibacterial Ti implants and highlighted the recent advances of the *** hope that this review will provide theoretical basis and technical support for the development of new Ti implant with antibacterial and osteogenic functions.

摘要：A new type of V-shaped photonic crystal fiber with elliptical air-holes is proposed to realize simultaneous high bire- fringence and nonlinearity at a wavelength of 1.55 μm. The full vector finite element method was adopted to investigate its characteristics, including birefringence, nonlinearity, and dispersion. The PCF exhibited a very high birefringence of 2.89x10-2 and very high nonlinear coefficient of 102.69 W-1 .km 1. In particular, there were two zero-dispersion wave- lengths （ZDWs） in the visible （X： 640-720 nm and Y： 730-760 nm） and near-infrared regions （X： 1050-1606 nm and Y： 850-1500 nm）. The combination of high birefringence and nonlinearity allowed the PCF to maintain the polarization state and generate a broadband super continuum, with potential applications in nonlinear optics.

摘要：The growth plate(GP)is a crucial tissue involved in skeleton development via endochondral ossification(EO).The bone organoid is a potential research model capable of simulating the physiological function,spatial structure,and intercellular communication of native ***,mimicking the EO process remains a key challenge for bone organoid *** simulate this orderly mineralization process,we designed an in vitro sh Ca_(v)3.3 ATDC5-loaded gelatin methacryloyl(Gel MA)hydrogel model and evaluated its bioprintability for future organoid *** this paper,we report the first demonstration that the T-type voltage-dependent calcium channel(T-VDCC)subtype Ca_(v)3.3 is dominantly expressed in chondrocytes and is negatively correlated with the hypertrophic differentiation of chondrocytes during the EO ***,Ca_(v)3.3 knockdown chondrocytes loaded with the Gel MA hydrogel successfully captured the EO process and provide a bioink capable of constructing layered and orderly mineralized GP organoids in the *** results of this study could therefore provide a potential target for regulating the EO process and a novel strategy for simulating it in bone organoids.

摘要：A series of novel poly（urethane-urea）（PUU） was synthesized from poly（lactide-co-p-dioxanone） macrodiol（HO-P（LA-co-PDO）-OH）, hexamethylene diisocyanate（HDI） and butanediamine（BDA）.The obtained PUU,which is recorded as P（LA-co-PDO）-PUU here,may demonstrate enhanced phase separation and thus improved shape memory *** was employed to characterize the copolymers,and the effects of NCO/OH molar ratios on Tg of PUU was investigated by means of differential scanning calorimetry （DSC）.The results revealed the successful synthesis of P（LA-co-PDO）-*** addition,the Tg of P（LA-co-PDO）-PUU increased from 37.9℃to 44.2℃with the increase NCO/OH ratios from 1.1 to *** P（LA-co-PDO）-PUU with Tg close to body temperature will have potential applications as shape memory polymers in biomedical fields,especially in minimally invasive surgery.

摘要：A new positively thermo-sensitive hydrogel was designed and synthesized by a condensation polymerization reaction of ethylenediaminetetraacetic dianhydride（EDTAD） and piperazine（PA） to give poly（ethylenediaminetetraacetic dianhydride-copiperazine） （PEP）.The obtained polymers＇ structure was characterized by FTIR and ^（13）C *** backbone of the polymer linked by amide bond and abundant of carboxyl groups as pendant group could form strong intermolecular and intramolecular hydrogen bond at lower temperature and dissociate at higher temperature,resulting in the polymer with *** aqueous solution of PEP at lower temperature（〈20℃） showed micro-gel formation and transformed to transparent solution at higher temperature（〉40℃）.Transition temperature shifted to higher value with the increasing of *** hydrogel exhibited reversible phase transition and the transmittance change was not weakened by multiple temperature changes.

摘要：This paper addresses the problem of channel estimation in 5G-enabled vehicular-to-vehicular(V2V) channels with high-mobility environments and non-stationary feature. Considering orthogonal frequency division multiplexing(OFDM) system, we perform extended Kalman filter(EKF) for channel estimation in conjunction with Iterative Detector & Decoder(IDD) at the receiver to improve the estimation accuracy. The EKF is proposed for jointly estimating the channel frequency response and the time-varying time correlation coefficients. And the IDD structure is adopted to reduce the estimation errors in EKF. The simulation results show that, compared with traditional methods, the proposed method effectively promotes the system performance.

摘要：The research on scroll profiles theory at present mainly is aiming at the single profile and its amelioration or parameter optimization,not aiming at the natural characteristic of the profiles equation of scroll profiles ***,the intrinsic differential equation bearing on arc-length and tangent direction angle was *** the inherent differential equation and general functional theory,the conversion ideas between the expression of intrinsic differential equation and the expression in Cartesian coordinate was studied,and the condition of involutes characteristic was *** detailed analysis of four typical scroll profiles was *** to the four typical scroll profiles and based on the method of Taylor series,the unified formation of general functional integration scroll profiles was established,which perfected general theory of scroll profiles *** envelope method to seek conjugation engagement profiles was *** unified general functional equation of scroll profiles represented the admissible function scrolls and the conjugation engagement characteristic of which was *** engagement condition of conjugation scroll profiles and the expression in Cartesian coordinate of conjugation scroll profiles of general functional integration scroll profiles were ***,the restriction of inherent characteristics of single scroll profiles model is broken *** modeling and machine tool path simulation can bridge the gap between design and manufacture which is essential for the design and manufacture of scroll *** this method a perfect solid model can be achieved,which leads to an optimal design in terms of quality,delivery time and *** presentation of unified formation of general functional integration scroll profiles represents foundation factor of instinct characteristics of scroll profiles,which widens the design method of scroll compressor for automobile air conditioning.

摘要：The combination of photoelectrochemical water oxidation hydrogen peroxide(H_(2)O_(2))on the anode and hydrogen evolution on the cathode increase the value of the water splitting ***,the sluggish water oxidation kinetics and slow carrier transport limit the generation of H_(2)O_(2).In this study,to promote H_(2)O_(2) production,the surface of a Mo doped BiVO_(4) photoanode was modified with CoO_(x) *** resulting CoO_(x)/Mo-BiVO_(4) photoanode generates H_(2)O_(2) at a rate of 0.39μmol min-1 cm–2 with a selectivity of 76.9%at 1.7 *** experimental results indicate that CoO_(x) decorated on Mo-BiVO_(4) kinetically favors the H_(2)O_(2) production via reduced band bending,while inhibiting H_(2)O_(2) *** to density functional theory calculations,the loading of CoO_(x) enhances the efficiency of the Mo-BiVO_(4) photoanode in generating H_(2)O_(2).Moreover,the in-situ generated H_(2)O_(2) through CoO_(x)/Mo-BiVO_(4) was applied to the degradation of tetracycline in aqueous solution,finding that CoO_(x)/Mo-BiVO_(4) exhibits the best performance among the catalysts *** work demonstrates that the CoO_(x) co-catalyst can effectively facilitate the water oxidation to H_(2)O_(2),opening a way for its application in situ water remediation.

摘要：(IGF-1 ) 像胰岛素的生长因素 1 支持造骨细胞区别和骨头形成，和它的表示被机械段导致，因此， IGF-1 被认为连接机械刺激和本地织物回答的一个受动器分子。在这研究，一台机械拉长设备被设计把生理的水平静电干扰或周期的拉长刺激用于造骨细胞。IGF-1 mRNA 的不同 isoforms 被 RT-PCR 用各自的教材从房间放大，这些放大产品被定序。产品被发现被造骨细胞有选择地在拉长刺激下面生产的拼接的 IGF-1 的 iso 形式。ThisIGF-1 isoform 与原来在肌肉细胞被识别的 mechano 生长因素(MGF ) 有相同顺序。肝类型 IGF (***-1 ) 和在在段刺激下面的造骨细胞的 MGF 的表示的规定进一步用半量的 RT-PCR 被学习。Stretchstimulation 被发现 IGF-1 (***-1 和 MGF ) 的表示到职业人员警句，并且为两 isoformsexpression，更多被周期的段有效地比静态的段刺激。MGF 仅仅在受到机械段的造骨细胞被检测，建议 MGF 是段敏感生长因素。MGF 的表示比 ***-1 的早达到顶点，它类似于他们在肌肉的规定并且作为在肌肉房间在骨头建议了 MGF 和 ***-1 的类似的角色。在造骨细胞的 MGF 和 ***-1 的功能将被进一步试验性的研究建立。

摘要：In this study,innovative ellipsoid pellet with craters on its surface was designed,and the direct reduction process was compared with ellipsoid(without craters)and sphere *** addition,furnace temperature and uneven heat flux density effects on the pellet direct reduction process were also *** results show that ellipsoid pellet is better than that of spherical pellet on metallization ***,under the condition of non-uniform heat flow,the ellipsoid pellet final metallization rate and zinc removal rate were *** the heat transfer effect of ellipsoid pellet with craters was not improved significantly,the metallization rate and zinc removal rate were found improved,which will have a cumulative effect on the pellets direct reduction process in rotary hearth *** varying furnace temperature conditions,the pellet temperature was higher than that of the constant furnace *** 1200 s,pellet Fe concentration increased to 123.6%,metallization rate and zinc removal rate increased to 113.7%and 102.2%,*** results can provide references for the carbon-containing pellet design used in rotary hearth furnace.