摘要：一般情况下,每年冬季是季节性流感高发季节,但在当前2019冠状病毒病(COVID-19)大流行期间,全球季节性流感活动呈“断崖式”下降。为应对即将到来的流感季节,亟需弄清这种前所未有的流感低水平流行的原因。本文中,我们探索了一种国家特异性推理模型,利用该模型估计中国、英国和美国这三个国家中佩戴口罩、人员流动变化(国际和国内)以及严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)干扰的影响。结果发现,在这些地区增加一周佩戴口罩的干预措施,流感活动可减少11.3%~35.2%。实施一周的限制人员流动措施对国际(1.7%~6.5%)和国内社区(1.6%~2.8%)的影响较小。2020年至2021年,仅佩戴口罩这一项干预措施就可使阳性率下降13.3%至19.8%。仅人员流动变化可使阳性率降低5.2%至14.0%,其中79.8%~98.2%归因于国际旅行限制。SARS-CoV-2干扰仅在2019年至2020年具有统计学显著效应。中国北方地区及英国的阳性百分比分别降低7.6%(2.4~14.4)和10.2%(7.2~13.6)。探索所得出的结果对了解非药物干预措施和其他呼吸系统疾病背景下的流感演变有一定意义,有助于制定卫生政策,并可为公共卫生措施的个性化设计提供信息。

摘要：With the ever-increasing demands of grid-scale energy storage,aqueous zinc-ion batteries(ZIBs)have garnered increasing attention around the ***,limited Zn^(2+)host materials have hindered the commercialization of ***,Mo-V oxides with different phase structures(orth-,tri-,and tetra-MoVO)were precisely constructed to develop phase-dependent Mo-V oxide cathodes for Zn^(2+)storage in *** open frameworks and varied tunnel structures formed a favorable alternative for achieving suitable Zn^(2+)diffusion *** optimized phase engineering,the high specific capacity of approximately 400 mA h g^(−1) and excellent cyclic stability of 1000 cycles were achieved with orth-MoVO as the *** large amount of six-and seven-member rings in the orth-MoVO phase,which allow for alternative Zn^(2+)insertion,play a vital role in hosting Zn^(2+)ions *** proposed phase engineering strategy provides a new approach toward cathode design in ZIBs.

摘要：As social and economic dynamics continue to evolve and the demand for companionship increases,pet ownership has become an increasingly popular lifestyle *** parks,as a new form of urban public space,are gaining significant *** study,grounded in the theory of spatial justice,employs a combination of questionnaires and semi-structured interviews to evaluate four representative pet parks in Hong Kong,*** explores how pet parks,as inclusive green infrastructure in high-density environments,contribute to urban community well-being and broader spatial *** study reveals the conflicts between pet owners and non-pet owners regarding the rights to use public spaces,examining how to guarantee the spatial rights of specific groups while avoiding harm to *** findings indicate that green space availability,sociability and participation,walkability,safety,and flexibility in pet parks play a positive role in achieving urban spatial ***,pet parks also face challenges related to social exclusion and safety,requiring a balance between promoting community integration and ensuring public *** study offers valuable insights for the development of pet parks,the creation of vibrant and diverse public spaces,and the promotion of harmonious human-animal environments in cities across China and other Asian countries.

摘要：Heart failure is common in older people and its prevalence is *** Heart ＇omics＇ in AGEing（HOMAGE） project aims to provide a biomarker approach that will improve the early diagnosis of heart failure.A large clinical database,based on（1） prospective population studies or（2） cross-sectional,prospective studies or randomized controlled trials（RCTs） of patients at risk for or with overt cardiovascular disease will be constructed to determine most promising ＇omics＇-based biomarkers to identify the risk of developing heart failure and/or *** studies,patient cohorts and RCTs are eligible for inclusion in the common database,if they received ethical approval to obtain and share data and have baseline information on cardiovascular risk ***,the HOMAGE database includes 43,065 subjects,from 20 studies in eight European countries,including healthy subjects from three population studies in France,Belgium and Italy（n = 7,124）,patients with heart failure（n = 4,312） from four cohorts in the UK,Spain and Switzerland and patients at high risk for cardiovascular disease（n = 31,629） in 13 *** is anticipated that more partners will join the consortium and enlarge the pooled *** large merged database will be a useful resource with which to identify candidate biomarkers that play a role in the mechanism underlying the onset and progression of heart failure.