摘要：The design of an ultra-compact SOI-based 1×2 3 dB multimode interference(MMI) coupler is *** symmetric multimode interference structure and deeply-etched parabolically tapered multimode waveguide are used in the *** length of the device is reduced by about 87% compared with general multimode interference straight *** on effective index method(EIM) and two dimensional beam propagation method(2D-BPM),the structure parameters are optimized and the fabrication tolerances are *** results indicate that the performance of the coupler is deeply affected by the coupler's width,etching depth and photolithography alignment error in perpendicular direction.

摘要：To the Editor： In a single-center, prospective randomized clinical study including 122 elderly patients undergoing the carotid endarterectomy （CEA）, Wang et al. showed that compared with propofol-based total intravenous anesthesia, low-dose sevoflurane inhalation along with propofol reduced the incidence of postoperative myocardial injury.

摘要：Maltose is a natural α-(1,4)-linked disaccharide with wide applications in food industries and microbial fermentation. However,maltose has scarcely been used for in vitro biosynthesis, possibly because its phosphorylation by maltose phosphorylase (MP)yields β-glucose 1-phosphate (β-G1P) that cannot be utilized by α-phosphoglucomutase (α-PGM) commonly found in in vitrosynthetic enzymatic biosystems previously constructed by our group. Herein, we designed an in vitro synthetic enzymaticreaction module comprised of MP, β-phosphoglucomutase (β-PGM), and polyphosphate glucokinase (PPGK) for thestoichiometric conversion of each maltose molecule to two glucose 6-phosphate (G6P) molecules. Based on this syntheticmodule, we further constructed two in vitro synthetic biosystems to produce bioelectricity and fructose 1,6-diphosphate (FDP),respectively. The 14-enzyme biobattery achieved a Faraday efficiency of 96.4% and a maximal power density of 0.6mW/cm^(2),whereas the 5-enzyme in vitro FDP-producing biosystem yielded 187.0mM FDP from 50 g/L (139mM) maltose by adopting afed-batch substrate feeding strategy. Our study not only suggests new application scenarios for maltose but also provides novelstrategies for the high-efficient production of bioelectricity and value-added biochemicals.

摘要：太阳能蒸发是一种可持续的高盐废水处理技术,然而运行中蒸发器表面的盐积累会严重缩短蒸发器的寿命.如何使蒸发器兼具高蒸发效率和良好拒盐性是目前面临的挑战.本研究设计了一种三维碳纳米纤维/氧化石墨烯复合气凝胶(CNF/GOA).氧化石墨烯的引入不仅增强了CNF/GOA的力学性能,同时构建了丰富的分级互连孔道结构,加快了水的传输和盐的扩散,实现了高蒸发速率和良好的拒盐性.此外,通过调控CNF/GOA的浸没深度和孔道结构,抑制了水的热传导损失,降低了水的蒸发焓,在一个太阳照射下实现了3.47 kg m^(-2)h^(−1)的蒸发速率.更重要的是,即使处理高盐水,蒸发器表面也没有产生任何盐结晶.长期实验和户外脱硫废水蒸发实验表明,CNF/GOA具有良好的实际应用前景.

摘要：CThe objective of the present study was to prepare solid self-nanoemulsifying drug delivery system(S-SNEDDS)containing Capryol-90 as oil phase for the delivery of Embelin,a poorly water soluble herbal active ***-Behnken experimental design was employed to optimise the formulation variables,X1(amount of oil;Capryol 90),X2(amount of surfactant;Acrysol EL 135)and X3(amount of co-surfactant;PEG 400).Systems were appraised for visual characteristics for self emulsifying time,globule size and drug *** liquid formulations were formulated into free flowing granules(S-SNEDDS)by adsorption on the porous materials like Aerosil 200 and Neusilin and thereby compressed into *** vitro dissolution studies of SNEDDS revealed increased in the dissolution rate of the ***-IR data revealed no physicochemical interaction between drug and *** state characterization of S-SNEDDS by DSC and Powder XRD confirmed reduction in drug crystallinity which further supports the results of dissolution *** analysis exhibited spherical ***,the accelerated stability studies for 6 months revealed that S-SNEDDS of Embelin are found to be stable without any significant change in physicochemical ***,the present studies demonstrated dissolution enhancement potential of porous carrier based S-SNEDDS for poorly water soluble herbal active ingredient,Embelin.

摘要：A 1 550 nm long-wavelength vertical cavity surface emitting laser(VCSEL)on InP substrate is designed and fabr *** transfer matrix is used to compute reflectivity spectrum of the designed epitaxial *** epitaxial layers mainly consist of 40 pairs of n-Al_(x )Ga_(y )In_((1-x-y))As/InP,and 6 strain compensated Al_(x )Ga_(y )In_((1-x-y))As/InP quantum wells on n-InP substrate,*** top distributed Bragg reflection(DBR)mirror system has been formed by fabricating 4.5 pairs of SiO_2/*** designed cavity mode is around 1 536 *** dip of the fabricated cavity mode is around 1 530 *** threshold current is 30 mA and the maximum output power is around 270μW under CW operation at room temperature.

摘要：On the basis of the FLP (frustrated Lewis pair) principle, a new strategy has been proposed to construct the "frustration" in de- signing metal-free hydrogen activation compounds, by using FMO (frontier molecular orbital) analyses and quantum mechanics calculations. Unlike the known FLPs which use bulky substituents to prevent them from forming stable Lewis acid/base com- plexes, the new approach encumbers the intramolecular π donation from the electron donor to the acceptor (e.g. in BH2NH2) by using a CH2 bridge (giving BH2CH2NH2). The strategy is simple and effective. Its effectiveness is demonstrated by the small hy- drogen activation energy (12.0 kcal/mol) of the model molecule (BH2CH2NH2), which is significantly less than the 42.7 kcal/mol of BH2NH2 and also less than the 18.5 kcal/mol of BH2PH2 whose derivative, R2PB(C6F5)2, has been experimentally shown to be able to activate hydrogen. We also exemplified how to use the strategy to design experimentally more realizable molecules. The example shows promises as a hydrogen activation agent. The strategy can be used to design metal-free catalysts for direct hydro-genation.

摘要：A 25-channel 200 GHz arrayed waveguide grating(AWG) based on Si nanowire waveguides is designed, simulated and fabricated. Transfer function method is used in the simulation and error analysis of AWG with width fluctuations. The 25-channel 200 GHz AWG exhibits central channel insertion loss of 6.7 dB, crosstalk of-13 dB, and central wavelength of 1 560.55 nm. The error analysis can explain the experimental results of 25-channel 200 GHz AWG well. By using deep ultraviolet lithography(DUV) and inductively coupled plasma etching(ICP) technologies, the devices are fabricated on silicon-on-insulator(SOI) substrate.

摘要：有在从 metalorganic 框架(ZIF-8 ) 导出的做氮的多孔的碳(NPC ) 上支持的不同作文的分散得好的二金属的 NiRh nanoparticles (NP ) 通过一个合作减小方法被综合。NPC-900 支持了 NiRh 催化剂展览向从肼的氢产生的最高催化的活动和 100% 氢选择。这些性质可能被归因于高表面区域和 NPC 的高 graphitization。这策略可以为由作为支持利用 NPC 抛锚设计高效的催化剂开创一条新大街为另外的应用的活跃金属 NP。

摘要：Antibody-based fusion proteins are the next generation of antibody therapies for cancer and other ***20 antigen,which is overexpressed on cell membranes in nearly 95% of cases of B-cell Non-Hodgkin's Lymphoma,is an attractive target for the therapy of B-lymphoid *** (LDM) is a potent enediyne-containing antitumor antibiotic that now has entered phase II clinical *** this study,we prepared an engineered fusion protein,scFv-LDP,consisting of an anti-CD20 scFv fragment and the apoprotein LDP of LDM using DNA *** purification and refolding,scFv-LDP was found to bind specifically to CD20-positive lymphoma cells using ELISA and indirect immunofluorescent cytochemical staining *** energized fusion protein scFv-LDP-AE was obtained using molecular reconstitution of the active chromophore AE of LDM and *** assay revealed potent cytotoxicity of scFv-LDP-AE to CD20-positive Raji and Daudi cells,with IC 50 values of 1.21×10-11 and 6.24×10-11 mol L-1,*** in vivo subcutaneous xenograft model of CD20-positive B cell lymphoma in BALB/c (nu/nu) mice was also *** were given intravenously on day 14 and 21 after tumor *** terms of maximal tolerated doses,scFv-LDP-AE at 0.3 mg kg-1 suppressed tumor growth by 79.3%,and LDM at 0.05 mg kg-1 by 68.6% (P<0.05).Results suggested scFv-LDP-AE could be a potential candidate for tumor-targeting therapy.