摘要：Ocean currents are one of important resources of ocean energy. Although it is not widely harnessed at present, ocean current power has a vital potential for future electricity generation. In fact, several turbine systems have been proposed in the world. In the present, we consider what factors should be considered in designing the system from the perspective of hydrodynamics. As an example, a floating Kuroshio turbine system which is under development in Taiwan is employed to serve as the case study. The system consists of five major parts; i.e. a foil float which can be employed to adjust the system submergence depth, a twin contrarotating turbine system for taking off the current energy, two nacelles housing power generators, a cross beam to connect two nacelle-and-turbine systems, and two vertical support to connect the foil float and the rest of the system.

摘要：Introduction In the past decade,three-dimensional(3D)bioprinting,which precisely deposits bioink composed of the biological materials and the living cells into delicate structures with the living cells encapsulated,has made numerous important advances in tissue engineering and regenerative medicine[1,2].Depending on the printing mechanism,3D bioprinting technologies are generally categorized into four types:inkjet-based bioprinting,microextrusion-based bioprinting,laser-assisted bioprinting,and stereolithography-based bioprinting[3].

摘要：Cell migration is facilitated by the interaction of living cells and their local *** local topography is one of the key factors regulating cell *** between the surface topography and the cell behaviors is critical to understanding tissue development and *** this study,a dynamic mask photolithography technique has been utilized to fabricate a surface with graded *** has been demonstrated that the cells have been successfully guided to migrate from the sparse zone to the dense *** cell polarization angle has been characterized in both sparse zone and the dense *** to the dense zone,the cells in the sparse zone are more aligned along the direction of the micropillar spacing gradient,which enables the guided cell ***,the effects of the micropillar spacing gradient,micropillar diameter,and micropillar height have been investigated in terms of the cell migration speed and cell spreading ***,two issues significantly affecting the cell migration have been discussed:trapped cells between the micropillars and cell clusters.

摘要：Optimization analysis and computational fluid dynamics （CFDs） have been applied simultaneously, in which a parametric model plays an important role in finding the optimal solution. However, it is difficult to create a parametric model for a complex shape with irregular curves, such as a submarine hull form. In this study, the cubic Bezier curve and curve-plane intersection method are used to generate a solid model of a parametric submarine hull form taking three input parameters into account： nose radius, tail radius, and length-height hull ratio （L/H）. Application program interface （API） scripting is also used to write code in the ANSYS DesignModeler. The results show that the submarine shape can be generated with some variation of the input parameters. An example is given that shows how the proposed method can be applied successfully to a hull resistance optimization case. The parametric design of the middle submarine type was chosen to be modified. First, the original submarine model was analyzed, in advance, using CFD. Then, using the response surface graph, some candidate optimal designs with a minimum hull resistance coefficient were obtained. Further, the optimization method in goal-driven optimization （GDO） was implemented to find the submarine hull form with the minimum hull resistance coefficient （Ct）. The minimum C, was obtained. The calculated difference in （7, values between the initial submarine and the optimum submarine is around 0.26%, with the C, of the initial submarine and the optimum submarine being 0.001 508 26 and 0.001 504 29, respectively. The results show that the optimum submarine hull form shows a higher nose radius （rn） and higher L/H than those of the initial submarine shape, while the radius of the tail （r1） is smaller than that of the initial shape.

摘要：目的揭示不同直径血管中复杂细胞运动形态对于传质的影响,有助于对人体内物质跨膜输运机制的理解。此外,作为潜在的药物输运载体,了解红细胞运动变形与传质之间的关系有助于设计更有效的药物传输方式。方法基于之前提出的浸入边界数值方法,对微循环复杂流动影响下的单细胞传质特性进行数值分析,讨论了细胞膜渗透系数、管道直径。