摘要：Eutectic and near-eutectic high entropy alloys （HEAs） have recently attracted a great deal of interest because of their promising properties, such as an excellent castability and unique combination of good ductility and high strength. However, in the absence of a phase diagram, it remains a non-trivial task to find a eutectic or near-eutectic composition for a HEA system, which usually demands a tremendous amount of efforts if a trial-and-error approach is followed. In this paper, we briefly review the thermodynamics that governs the entectic solidification in regular binary and ternary alloys, and proceed to the discussion for the design of eutectic HEAs. Based on the data reported, we then propose an improved strategy which may enable an efficient search for the eutectic or near eutectic HEA compositions.

摘要：This paper presents a design for a self-powered radio frequency identification (RFID) tag with a thin film bulk acoustic reso- nating piezoelectric power supply (PPS), which can be used for portable remote temperature monitoring. We call this system a PPS-RFID for short. The RFID systems have been found to have many applications in the internet of things (IOT) in the past decade. But semi-active RFID tags require an onboard battery which limits their applications in many fields. For these reasons, our research focuses on power sources for the RFID tags. This paper emphasizes the circuit design and simulation of PPS. In our tests, 0.283 mW was generated by PPS at 1 Hz vibration by a 650 N impact force. The results showed that the integrated PPS could supply sufficient power for the designed PPS-RFID tag. The PPS-RFID tag can be widely used for temperature monitoring during mobile transport of perishable items such as medicines or food.

摘要：The application of thermoelectric devices(TEDs)for personalized thermoregulation is attractive for saving energy while balancing the quality of *** that directly attach to human skin remarkably minimized the energy wasted for cooling the entire ***,facing the extreme dynamic geometry change and strain of human skin,conventional TEDs cannot align with the contour of our bodies for the best thermoregulation ***,we designed a kirigami-based wearable TED with excellent water vapor permeability,flexibility,and *** analysis and experimental results reveal that our product can withstand various types of large mechanical deformation without circuit *** stated outcome and proposed facile approach not only reinforce the development of wearable TEDs but also offer an innovative opportunity for different electronics that require high conformability.

摘要：The lifespan of biological heart valve prostheses available in the market is limited due to structural alterations caused by calcium phosphate deposits formed from blood plasma in contact with the *** objective of this work is to present a comparative methodology for the investigation of the formation of calcium phosphate deposits on bioprosthetic and tissue-engineered scaffolds in vitro and the influence of mechanical forces on tissue *** on earlier investigations on biological mineralization at constant supersaturation,a circulatory loop simulating dynamic blood flow and physiological pressure conditions was *** system was appropriately adapted to evaluate the calcification potential of decellularized(DCV)and glutaraldehyde-fixed(GAV)porcine aortic *** indicated that DCV calcified at higher,statistically nonsignificant,rates in comparison with *** difference was attributed to the tissue surface modifications and cell debris leftovers from the decellularization *** analysis of the solids deposited after 20 h by scanning electron microscopy in combination with chemical microanalysis electron-dispersive spectroscopy identified the solid formed as octacalcium phosphate(Ca8(PO4)6H2·5H2O,OCP).OCP crystallites were preferentially deposited in high mechanical stress areas of the test ***,GAV tissues developed a significant transvalvular pressure gradient increase past 36 h with a calcium deposition distribution similar to the one found in explanted *** conclusion,the presented in vitro circulatory model serves as a valuable prescreening methodology for the investigation of the calcification process of bioprosthetic and tissue-engineered valves under physiological mechanical load.

摘要：In recent decades,the application of seismic metamaterials to protect civil infrastructures being free of the damage of earthquakes has been attracting extensive ***,the proposed locally resonant seismic metamaterials provide the probability of isolating the low-frequency seismic wave using a small-size isolation ***,in previous studies,the energy absorption properties of locally resonant seismic metamaterials remain one of the least understood aspects of *** from the fascinating energy absorption characteristic of negative Poisson ratio(NPR)metamaterial,we creatively design a new seismic metamaterial structure by assembling the locally resonant seismic metamaterial and NPR metamaterial,to isolate seismic *** sound cone technique combining the transmission spectrum is employed to identify the surface wave from the hybrid *** generation mechanism of frequency bandgap and the isolation effectiveness of the proposed seismic metamaterial are discussed in *** results indicate that the generation of ultra-low and ultra-wide frequency bandgap with the range of 0.65 Hz–18.9 Hz is attributed to the locally resonant and energy absorption of the proposed seismic metamaterial structure and the excellent isolation effect is achieved by transforming the surface wave into the bulk *** frequency bandgap narrows as the distance increases between each *** addition,the mechanical properties of the NPR bearing,such as the Poisson ratio,mass density,and elastic modulus,have remarkable impact on the frequency bandgap,especially on the upper bound *** practical engineering,the NPR bearing with a low Poisson ratio,small mass density,and high elastic modulus is suggested for the design of the NPR locally resonant seismic metamaterial *** domain analysis for the practical seismic wave verifies that the proposed seismic metamaterial has a promising application in isolating ultra-low and ultra-wi

摘要：Tissue engineering approaches,including those to functional lung tissues,are finely honed by the inclusion of upgraded devices that mimic biophysical and biochemical features in *** culture is one of these essential biophysical characteristics enabled by the introduction of microfluidic devices in recent *** review links the importance of dynamic culture for in vitro maintenance of functional lung cells to the modeling of respiratory *** identify and discuss different parameters for fabricating the requisite microfluidic models for lung cells,as well as their application in modeling lung diseases caused by external factors such as smoking and *** possibility of creating a multi-organ-on-a-chip to establish a more physiologically relevant model is ***,the focus is on different prospects for the in vitro modeling approach and for lungs-on-a-chip for developing advanced,reliable technology to analyze the pathophysiology of respiratory diseases and screen potential treatments.

摘要：Recently,Kelly and colleagues[1],inspired by computed tomography(CT),report a“volumetric additive manufacturing”technology via a computed axial lithography(CAL)approach.A related US patent application[2]has also been *** cumulative light exposure solidifies the material in the target area,while the other area remains uncured,resulting in only specific points in the designed 3D objects being *** technology significantly improves the capability of the digital light processing(DLP)***,the lithography approach based on a similar algorithm was already proposed by Xiang Wu in a patent(application ***/CN2016/080097)in 2016[3].

摘要：OverviewThe Research Lab on 3D Bioprinting of Zhejiang University focuses on developing innovative 3D bioprinting equipment and technology for healthcare and biomedical applications, since founded in 2017. To further enhance the international collaboration, a joint international research lab on 3D bioprinting of Zhejiang University and University of Oxford was set up. The lab is based on the State Key Laboratory of Fluid Power and Mechatronic Systems and the Oxford Centre for Tissue engineering and Bioprocessing. The aim of the lab is to establish a world class research and development platform on 3D bioprinting. The lab has extensive and close collaborations with University of Oxford, University College London and multidisciplinary partners of Zhejiang University.

摘要：Three-dimensional （3D） printing is a novel promising technology based on 3D imaging and layer-by-layer additive fabrication. It has a profound influence on all aspects of our lives and is playing an increasing important role in many areas including engineering, manufacturing, art, education and medicine. ＂3D bioprinting＂ has been put forward with the technical progress in 3D printing and might be a possible way to solve the serious problem of human organ shortage in tissue engineering and regenerative medicine. Many research groups flung them into this area and have already made some gratifying achievements. However, it is a long way to fabricate a live organ. Many elements lead to the limitation of 3D bioprinting. This review introduces the background and development history of 3D bioprinting, compares different approaches of 3D bioprinting and illustrates the key factors of the printing process. Meanwhile, this review also points out existing challenges of 3D bioprinting and has a great prospect. Some points proposed in this review might be served as reference for the research of this field.

摘要：New multilayer coatings were produced by incorporating alternating soft and hard DLC layers enabled by varying the bias voltage during deposition process while maintaining a constant hard-to-soft layer thickness *** coatings were deposited onto a Cr/Cr Cxgraded layer by closed field unbalanced magnetron sputtering(CFUBMS).The cross-sectional analysis of the coatings showed that the multilayer coatings possess sharp interfaces between the soft and hard layers with the hard to soft layer thickness ratio(1:1.33)constant in all the *** analysis uncovered the increasing sp^(3)character of the DLC coatings as a result of decreasing ID/IGratio and increasing full width at half maximum(FWHM)values of the G band peak induced supposedly by an increase in bias voltage during hard layer *** tests showed an increase in hardness of the DLC coatings which can be correlated with the increase in the sp^(3)content of the coatings as well as decreasing sp^(2)-C cluster size,as calculated from the ID/***,the coatings exhibited excellent plastic deformation resistance and adhesion strength upon microindentation and scratch testing,*** further investigations are required to assess coating durability,the multilayer design could offer the DLC coatings with a rare opportunity to combine the high hardness with damage resistance with a constant bilayer thickness and without the need to introduce complex multilayer system.