摘要：Hydrogen is a promising sustainable energy to replace fossil fuels owning to its high specific energy and environmental *** water electrolysis has been considered as one of the most prospective technologies for large scale hydrogen *** boost the sluggish kinetics of hydrogen evolution reaction(HER)in alkaline media,abundant materials have been designed and ***,we summarize the key achievements in the development of layered transition-metal hydroxides[TM(OH)x]for efficient alkaline *** on the structure of TM(OH)x,the mechanism of synergistic effect between TM(OH)x and HER active materials is illuminated ***,recent progress of TM(OH)x-based HER catalysts to optimize the synergistic effect are categorized as TM(OH)x and active materials,including species,structure,morphology and interaction ***,TM(OH)x-based overall water splitting electrocatalysts and electrodes are summarized in the design principles for high activity and ***,some of key challenges for further developments and applications of hydrogen production are proposed.