摘要：Diamides acting on insect ryanodine receptors are an intensive research area now. In order to search for novel candidates, a series of diamides containing biphenyl substructure were designed and *** insecticidal activities against armyworms（Mythimna sepatara） and aphis（Aphis craccivora） were screened. The compounds with 3,5-dichloro-4-（1,1,2,2-tetrafluoroethoxy）phenyl substituent were found to be insecticidal to armyworms with the similar symptoms to poisoning by flubendiamide. In this research, we presented a novel type of diamide insecticide as a lead compound for further optimization.

摘要：Spiro heterocycles frequently occur in bioactive molecules. In the pursuit of neonicotinoids with spiro hererocycles, three types of novel neonicotinoids with spirobenzofuranone, spirooxindole or spiroacenaphythylenone framework were designed and synthesized. Insecticidal evaluation showed that some of spirobenzofuranone containing neonicotinoids exhibited moderate activity against cowpea aphid, armyworm or brown planthopper.

摘要：Recently service orientation is becoming a mainstream approach for building large scale software systems. A key requirement in service-oriented design is the dependability of service. It stipulates that the behavior of services is controllable. Formal models can aid in constructing software in a dependable manner. They can describe ser- vices precisely and compose them together consistently. This paper presents a strategy for service realization based on a novel layered formal model. When a service is provided or required via internet, the semantic consistency becomes critical issue, Our architecture tackles the issue by proposing a novel scheme： defining contract of a service to keep semantic information. Although service-oriented design is our prime target, the contract models, to a large extent, are independent of the framework of design and therefore applicable to large scale software design in general.

摘要：A convenient and scalable synthesis of 1-amino-5-cyanonaphthalene was described.

摘要：A series of novel anthranilic diamides with benzyl sulfide scaffold were synthesized,in which N-pyridylpyrazole moiety generally regarded as key pharmacophore was *** target compounds were characterized by ~1H NMR,^（13）C NMR,^（19）F NMR and *** preliminary bioassays indicated that half of the title compounds were endowed with good insecticidal activities against armyworm（Mythimna sepatara） at the concentration of 500 mg/L,Exhilaratingly,the synthesized compound 3a was also active against Tetranychus cinnabarinus at 100 mg/*** difference in activities between the target compounds was influenced by the substituents,which provided some hints for further investigation on structure modifications.

摘要：For the first-order integrating processes with long delay, a Modified Smith Predictor (MSP) was analyzed when the control signal saturated. If the MSP controller has no anti-windup scheme, the saturation effectively chops off the control input resulting in performance deterioration. Thus, a simple and effective anti-windup scheme, without an additional parameter, is designed for the MSP. Simulation results illustrate that the proposed method may achieve good performance under the nominal and model uncertainty cases.

摘要：The dynamic analysis and optimal design of reactive extraction are challenging due to high nonlinearity of model equations and tough decision of judging criteria. In this work, a dynamic rate-based method is developed on g PROMS platform to get easy access to the solutions of reactive extraction with phase splitting. Based on rigorous criteria, dynamic analysis from initial state to final equilibrium(e.g., evolution of phase composition, mass transfer rate and reaction rate) and optimal design of operating conditions(e.g., extractant dosage and feed molar ratio) are achieved. To illustrate the method, the esterification of n-hexyl acetate is taken as an example. The approach proves to be reliable in the analysis and optimization of the exemplified system, which provides instructive reference for further process design and simulation of reactive extraction.

摘要：Chlorothiazole ring, as a substituted heterocycle, frequently occurred in structures of various insecticides, and brought positive effect on bioactivity. In purpose to find novel neonicotinoids, a series of pyrrole- and dihydropyrrole-fused neonicotinoid analogs containing chlorothiazole ring were synthesized for the first time. Results of the following biological assays showed that compounds Sa-c achieved good insecticidal activity against Aphis craccivora, and compound Sh exhibited good activity against Nilaparvata lugens.

摘要：In order to monitor deformation of high temperature components for a long time,a sensing device integrating a bridge-shaped mechanical displacement amplifier has been *** sensing device has higher resolution and accuracy than conventional ***,the relation between the magnification ratio and the structure size of the displacement amplifier is a bottleneck of sensing device *** this,the magnification ratio of a mechanical displacement amplifier is analytically derived based on its geometry *** prototypes of the displacement amplifier made in propathene are manufactured,and an experimental system is set up to validate the accuracy of the established magnification ratio *** magnification ratios and experimental magnification ratios are compared and agree well,which verifies that the proposed equation is *** analytical equation provides an effective design method for bridge-shaped mechanical displacement amplifiers with an expected magnification ratio.

摘要：In order to discover new generation of triazole antifungal agents,a series of novel antifungal triazoles were designed and synthesized by structural simplification of our previously identified triazolepiperdine-heterocycle lead *** target compounds showed good antifungal activity with a broad *** particular,compound 71 was highly active against Candida albicans and Candida ***,compound 71 showed potent in vivo antifungal efficacy in the Caenorhabditis *** infection model.