摘要：In a recent publication [1], these images in Figures 6(b, c)(^NPEG-NPCe6 group), S7, S9 and S10 were inadvertently taken the incorrect images in the production. The corrected versions are shown below. And, the quantification of Ce6 fluorescence(as performed in Figure 6(c)) was also corrected(Figure S12).

摘要：Introduction The concept of“gradients”has been widely demonstrated and applicated in *** example,concentration gradients and potential gradients in the body can regulate the homeostasis as well as the balance of physiological environment;oxygen gradients play a vital role in cellular gene expression and migration.

摘要：There is a consensus that the prevention of wound infection should be achieved in the following ways:(1)closing the wound to protect it from extra infection;(2)an antibacterial agent that could kill endogenous ***,existing bulk two-dimensional antibacterial materials show inefficient adhesion to wounds with complex morphology and thus cause the prevention of wound *** the thickness of bulk two-dimensional materials to less than 100 nanometres endows them with great flexibility,which could allow them to adhere to wounds with complex morphology by only physical ***,a broad-spectrum and efficient antimicrobial peptide(AMP)was introduced to biocompatible methacrylated gelatine(GelMA)with multiple modification sites,which served as an inner antibacterial *** being combined with a biodegradable and good mechanical poly-l-lactide(PLLA)outer layer through plasma-treatment-assisted spin coating,we finally constructed bilayered antibacterial nanosheets with a thickness of approximately 80 *** bilayered nanosheets possess good adhesion to surfaces with complex topography and thus achieve better wound closure than other bulk two-dimensional ***,this AMP-grafted conjugation shows minimal cytotoxicity compared with Ag^+antibacterial agents,and the antibacterial rate of nanosheets is dependent on the graft rate of *** suggest that this bilayered antibacterial nanosheet might be an advanced anti-infection dressing for wound treatment in clinical settings.

摘要：Metabolites play important roles in numerous cell biology processes,such as cell proliferation,differentiation,stress response,and cell death[1].Recently,lactate and lactate-derived lysine residue lactylation(Kla)have emerged as newly discovered epigenetic modifications that play critical roles in various physiological and pathological *** the history of lactate research,we can categorize the studies into three mile stones(Fig.S1 online).