摘要：Four-dimensional(4D)printing is an advanced form of three-dimensional(3D)printing with controllable and programmable shape transformation over *** are used as a controlling factor with multi-stage shape recovery,with emerging opportunities to customize the mechanical properties of bio-inspired *** print pattern of shape memory polymer(SMP)fbers strongly afects the achievable resolution,and consequently infuences several other physical and mechanical properties of fabricated ***,the deformations of bio-inspired structures due to actuator layout are more complex because of the presence of the coupling of multi-directional *** this study,the initial structure was designed from closed-shell behavior and divided into a general unit and actuator unit,the latter responsible for driving the *** stress confrontation between the actuator and the general unit was considered in the layout thermodynamic model,in order to eliminate the transformation produced by the uncontrolled shape memory behavior of the general *** critical and efective strategies for the layout design of actuators were proposed and then applied to achieve the desired accurate deformation of 3D-printed bilayer ***,the proposed approach was validated and adopted for fabricating a complex shell-like gripper structure.

摘要：High-energy rotor uncontained failure can cause catastrophic damage effects to aircraft systems if not addressed in design. In this paper, numerical simulations of three high-energy rotor disk fragments impacting on U type protection rings are carried out using LS-DYNA. Protection rings with the same mass and different groove depths are designed to study the influence of the groove depth. Simulation results including kinetic energy and impact force variation of single frag- ment are presented. It shows that the groove depth infects both the axial containment ability of the protection ring and the transfer process of energy. The depth of groove ought to be controlled to an appropriate value to meet both the requirement of axial containment and higher safety factor. Ver- ification test on high-speed spin tester has been conducted and shows that protection ring with appropriate U structure can resist the impact of the disk burst fragments. The ring is inflated from a circular to an oval-triangle shape. The corresponding simulation shows good agreement with the test.

摘要：Liver injury is a common cause of drug approval withdrawal during drug development,pre-clinical research,and clinical *** not properly treated,patients with severe liver injury can suffer from acute liver failure or even ***,utilization of the convenient in vitro hepatotoxicity assessment model for early detection of drug-induced hepatotoxicity is vital for drug development and safe personalized ***(e.g.,hydrogels,nanofibers,decellularized liver matrix)and bioengineering technologies(e.g.,microarrays,micropatterns,3D printing,and microfluidics)have been applied for in vitro hepatotoxicity assessment *** review summarizes the structure and functions of the liver as well as the components of in vitro hepatotoxicity assessment *** addition,it highlights the latest advances in developing hepatotoxicity models with the ultimate goal of further clinical translation.

摘要：Vectored non-covalent interactions—mainly hydrogen bonding and aromatic interactions—extensively contribute to(bio)-organic self-assembling processes and significantly impact the physicochemical properties of the associated ***,vectored non-covalent interaction-driven assembly occursmainly along one-dimensional(1D)or three-dimensional(3D)directions,and a two-dimensional(2D)orientation,especially that of multilayered,graphene-like assembly,has been reported *** this present research,by introducing amino,hydroxyl,and phenyl moieties to the triazine skeleton,supramolecular layered assembly is achieved by vectored non-covalent *** planar hydrogen bonding network results in high stability,with a thermal sustainability of up to about 330°C and a Young’s modulus of up to about 40 *** introducing wrinkles by biased hydrogen bonding or aromatic interactions to disturb the planar organization,the stability ***,the intertwined aromatic interactions prompt a red edge excitation shift effect inside the assemblies,inducing broad-spectrum fluorescence covering nearly the entire visible light region(400–650 nm).We show that bionic,superhydrophobic,pillar-like arrays with contact angles of up to about 170°can be engineered by aromatic interactions using a physical vapor deposition approach,which cannot be realized through hydrogen *** findings show the feasibility of 2D assembly with engineerable properties by modulating vectored non-covalent interactions.

摘要：High spatiotemporal resolution brain electrical signals are critical for basic neuroscience research and high-precision focus diagnostic localization,as the spatial scale of some pathologic signals is at the submillimeter or micrometer *** entails connecting hundreds or thousands of electrode wires on a limited *** study reported a class of flexible,ultrathin,highdensity electrocorticogram(ECoG)electrode *** challenge of a large number of wiring arrangements was overcome by a laminated structure design and processing technology *** flexible,ultrathin,high-density ECoG electrode array was conformably attached to the cortex for reliable,high spatial resolution electrophysiologic *** minimum spacing between electrodes was 15μm,comparable to the diameter of a single *** hundred electrodes were prepared with an electrode density of 4444 mm^(-2).In focal epilepsy surgery,the flexible,high-density,laminated ECoG electrode array with 36 electrodes was applied to collect epileptic spike waves inrabbits,improving the positioning accuracy of epilepsy lesions from the centimeter to the submillimeter *** flexible,high-density,laminated ECoG electrode array has potential clinical applications in intractable epilepsy and other neurologic diseases requiring high-precision electroencephalogram acquisition.

摘要：To design a promising Al−Si filler alloy with a relatively low melting-point,good strength and plasticity for the Cu/Al joint,the Cu,Ni,Zr and Er elements were innovatively added to modify the traditional Al−Si eutectic *** microstructure and mechanical properties of filler alloys and Cu/Al joints were *** result indicated that the Al−Si−Ni−Cu filler alloys mainly consisted of Al(s,s),Al_(2)(Cu,Ni)and Si(s,s).The Al−10Si−2Ni−6Cu filler alloy exhibited relatively low solidus(521℃)and liquidus(577℃)temperature,good tensile strength(305.8 MPa)and fracture elongation(8.5%).The corresponding Cu/Al joint brazed using Al−10Si−2Ni−6Cu filler was mainly composed of Al_(8)(Mn,Fe)_(2)Si,Al_(2)(Cu,Ni)3,Al(Cu,Ni),Al_(2)(Cu,Ni)and Al(s,s),yielding a shear strength of(90.3±10.7)*** joint strength was further improved to(94.6±2.5)MPa when the joint was brazed using the Al−10Si−2Ni−6Cu−0.2Er−0.2Zr filler ***,the(Cu,Ni,Zr,Er)-modified Al−Si filler alloy was suitable for obtaining high-quality Cu/Al brazed joints.

摘要：Natural chromophores wildly exist in living bodies and have been utilized for thousands of years[1].Many of them,such as quinine[2],luciferin[3-5],coelenteramide[6,7],and coumarin[8],can fluoresce and have been widely applied in biosensor,immune sensor,and fluorescent imaging agents[9,10].

摘要：面向纤维复合材料与结构的优化设计需要,建立高效准确的纤维复材细观力学仿真工具具有重要意义.本文首次提出了包含内嵌纤维的三维计算晶粒(computational grains),用于纤维增强复合材料的直接细观力学建模,基于所开发的纤维计算晶粒方法,可以直接构造含有多根随机分布纤维的代表性体积单元(RVE).此外,本文提出了一种基于缩放柱调和函数的Papkovich-Neuber解来表征纤维和基体中独立的Trefftz试函数位移场,并且开发了一种新的多场边界变分原理来计算纤维计算晶粒的刚度矩阵.数值算例表明,对于内嵌大量随机分布纤维的RVE,纤维计算晶粒不需要构造复杂的网格,即可快速计算RVE的精确应力场,并预测其有效力学性能.此外,这也是内嵌纤维的三维有限元单元的首次提出.

摘要：Proton exchange membrane(PEM)fuel cell has been regarded as a promising approach to the decarbonization and diversification of energy *** recent years,durability and cost issues of PEM fuel cells are increasingly significant with the rapid increase of power ***,the failure to maintain the cell consistency,as one major cause of the above issue,has attracted little ***,this study intends to figure out the underlying cause of cell inconsistency and provide solutions to it from the perspective of multi-physics transport coupled with electrochemical *** PEM fuel cells with electrodes under two compression modes are firstly discussed to fully explain the relationship of cell performance and consistency to electrode structure and multi-physics *** result indicates that one main cause of cell inconsistency is the intrinsic conflict between the separated transport and cooperated consumption of oxygen and electron throughout the active ***,a mixed-pathway electrode design is proposed to reduce the cell inconsistency by enhancing the mixed transport of oxygen and electron in the *** is found that the mixing of pathways in electrodes at under-rib region is more effective than that at the under-channel region,and can achieve an up to 40%reduction of the cell inconsistency with little(3.3%)sacrificed *** addition,all the investigations are implemented based on a self-developed digitalization platform that reconstructs the complex physical–chemical system of PEM fuel *** fully observable physical information of the digitalized cells provides strong support to the related analysis.

摘要：Three-dimensional(3D)printing has attracted increasing research interest as an emerging manufacturing technology for devel-oping sophisticated and exquisite architecture through hierarchical *** has also been employed in various advanced industrial *** development of intelligent biomedical engineering has raised the requirements for 3D printing,such as flexible manufacturing processes and technologies,biocompatible constituents,and alternative ***,state-of-the-art 3D printing mainly involves inorganics or polymers and generally focuses on traditional industrial fields,thus severely limiting applications demanding biocompatibility and *** this regard,peptide architectonics,which are self-assembled by programmed amino acid sequences that can be flexibly functionalized,have shown promising potential as bioinspired inks for 3D ***,the combination of 3D printing and peptide self-assembly poten-tially opens up an alternative avenue of 3D bioprinting for diverse advanced ***,a small but innovative nation,has significantly contributed to 3D bioprinting in terms of scientific studies,marketization,and peptide architectonics,including modulations and applications,and ranks as a leading area in the 3D bioprinting *** review summarizes the recent progress in 3D bioprinting in Israel,focusing on scientific studies on printable components,soft devices,and tissue *** paper further delves into the manufacture of industrial products,such as artificial meats and bioinspired supramolecular architectures,and the mechanisms,physicochemical properties,and applications of peptide ***,Israel contributes significantly to the field of 3D bioprinting and should thus be appropriately recognized.