摘要：Herein,two asymmetric hexacyclic fused small molecule acceptors(SMAs),namely BP4F-HU and BP4F-UU,were *** elongated outside chains in the BP4F-UU molecule played a crucial role in optimizing the morphology of blend film,thereby improving charge mobility and reducing energy loss within the corresponding ***,the PM6:BP4F-UU device exhibited a higher open-circuit voltage(V_(oc))of 0.878 V compared to the PM6:BP4F-HU device with a V_(oc)of 0.863 ***,a new wide bandgap SMA named BTP-TA was designed and synthesized as the third component to the PM6:BP4F-UU host binary devices,which showed an ideal complementary absorption spectrum in PM6:BP4F-UU *** addition,BTP-TA can achieve efficient intermolecular energy transfer to BP4F-UU by fluorescence resonance energy transfer(FRET)pathway,due to the good overlap between the photoluminescence(PL)spectrum of BTP-TA and the absorption region of ***,ternary devices with 15wt%BTP-TA exhibits broader photon utilization,optimal blend morphology,and reduced charge recombination compared to the corresponding binary ***,PM6:BP4F-UU:BTP-TA ternary device achieved an optimal power conversion efficiency(PCE)of 17.83%with simultaneously increased V_(oc)of 0.905 V,short-circuit current density(J_(sc))of 26.14 mA/cm^(2),and fill factor(FF)of 75.38%.

摘要：The subthalamic nucleus(STN)is considered the best target for deep brain stimulation treatments of Parkinson’s disease(PD).It is difficult to localize the STN due to its small size and deep *** microelectrode arrays(MEAs)can rapidly and precisely locate the STN,which is important for precise *** this paper,16-channel MEAs modified with multiwalled carbon nanotube/poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)(MWCNT/PEDOT:PSS)nanocomposites were designed and fabricated,and the accurate and rapid identification of the STN in PD rats was performed using detection sites distributed at different brain *** results showed that nuclei in 6-hydroxydopamine hydrobromide(6-OHDA)-lesioned brains discharged more intensely than those in unlesioned *** addition,the MEA simultaneously acquired neural signals from both the STN and the upper or lower boundary nuclei of the ***,higher values of spike firing rate,spike amplitude,local field potential(LFP)power,and beta oscillations were detected in the STN of the 6-OHDA-lesioned brain,and may therefore be biomarkers of STN *** with the STNs of unlesioned brains,the power spectral density of spikes and LFPs synchronously decreased in the delta band and increased in the beta band of 6-OHDA-lesioned *** may be a cause of sleep and motor disorders associated with ***,this work describes a new cellular-level localization and detection method and provides a tool for future studies of deep brain nuclei.

摘要：This paper presents a systematic investigation and demonstration of a K-band circularly polarized liquidcrystal-based phased array(LCPA),including the design,over-the-air(OTA)in-array calibration,and experimental *** LCPA contains 16 phase-shifting radiating channels,each consisting of a circularly polarized stacked patch antenna and a liquid-crystal-based phase shifter(LCPS)based on a loaded differential line *** to its slow-wave properties,the LCPS exhibits a maximum phase-shifting range of more than 360°with a figure of merit of 78.3(°)·dB^(-1)based on a liquid crystal layer with a thickness of only 5μ***,an automatic OTA calibration based on a state ergodic method is proposed,which enables the extraction of the phase-voltage curve of every individual LCPA *** proposed LCPA is manufactured and characterized with a total profile of only 1.76 mm,experimentally demonstrating a scanned circularly polarized beam from-40°to+40°with a measured peak gain of 12.5 dBic and a scanning loss of less than 2.5 *** bandwidth of the LCPA,which satisfies the require-ments of port reflection(|S_(11)|)<-15 dB,an axial ratio(AR)<3 dB,beam squinting<3°,and a gain variation<2.2 dB,spans from 25.5 to 26.0 *** total efficiency is about 34%,which represents a new state of the *** use of the demonstrated low-profile LCPA to support circularly polarized scanning beams,along with the systematic design and calibration methodology,holds potential promise for a variety of millimeter-wave applications.

摘要：Traditional tumor models do not tend to accurately simulate tumor growth in vitro or enable personalized treatment and are particularly unable to discover more beneficial targeted *** address this,this study describes the use of threedimensional(3D)bioprinting technology to construct a 3D model with human hepatocarcinoma SMMC-7721 cells(3DP-7721)by combining gelatin methacrylate(GelMA)and poly(ethylene oxide)(PEO)as two immiscible aqueous phases to form a bioink and innovatively applying fluorescent carbon quantum dots for long-term tracking of *** GelMA(10%,mass fraction)and PEO(1.6%,mass fraction)hydrogel with 3:1 volume ratio offered distinct pore-forming characteristics,satisfactorymechanical properties,and biocompatibility for the creation of the 3DP-7721 *** analysis and quantitative real-time fluorescence polymerase chain reaction(PCR)were used to evaluate the biological properties of the *** with the two-dimensional culture cell model(2D-7721)and the 3D mixed culture cell model(3DM-7721),3DP-7721 significantly improved the proliferation of cells and expression of tumor-related proteins and ***,we evaluated the differences between the three culture models and the effectiveness of antitumor drugs in the three models and discovered that the efficacy of antitumor drugs varied because of significant differences in resistance proteins and genes between the three *** addition,the comparison of tumor formation in the three models found that the cells cultured by the 3DP-7721 model had strong tumorigenicity in nude *** evaluation of the levels of biochemical indicators related to the formation of solid tumors showed that the 3DP-7721 model group exhibited pathological characteristics of malignant tumors,the generated solid tumors were similar to actual tumors,and the deterioration was *** research therefore acts as a foundation for the application of 3DP-7721 models in drug devel

摘要：应用3D打印技术制备准固态微型超级电容器(MSCs)在可编程结构设计和高质量负载电极制造方面具有固有的优势.然而,缺乏高性能的可打印墨水和厚电极内缓慢的离子传输,对其实际电荷存储能力提出了重大挑战.本文成功开发了一种具有优异流变性能的新型NiCo_(2)S_(4)基纳米复合墨水,并结合直墨书写的3D打印技术合理设计了准固态MSCs的三维结构.得益于牢固锚定在还原氧化石墨烯(rGO)表面的NiCo_(2)S_(4)纳米颗粒和有序的三维微孔,锯齿状厚电极提供了丰富的反应位点并增强了离子传输.因此,三层锯齿状MSCs的面电容高达416.7 mF cm^(-2).在1 mA cm^(-2)的电流密度下,单层、双层和三层电极的锯齿状MSCs的面电容与相对应的网格状MSCs相比,分别增加了127.1%、349.8%和585.9%.本工作为高面电容MSCs的材料和电极结构的跨尺度设计提供了新见解,推动了MSCs在柔性便携式电子设备中的集成应用研究.

摘要：A combination of hydrogels and microfluidics allows the construction of biomimetic three-dimensional(3D)tissue models in vitro,which are also known as *** hydrogel patterningwith awell-controlled spatial distribution is typically achieved by embedding sophisticated microstructures to act as a ***,these physical barriers inevitably expose cells/tissues to a less physiologically relevant microenvironment than in vivo ***,we present a novel dissolvable temporary barrier(DTB)strategy that allows robust and flexible hydrogel patterning with great freedom of design and desirable flow stimuli for cellular *** key aspect of this approach is the patterning of a water-soluble rigid barrier as a guiding path for the hydrogel using stencil printing technology,followed by a barrier-free medium perfusion after the dissolution of the *** and multiple tissue compartments with different geometries can be established using either straight or curved DTB *** effectiveness of this strategy is further validated by generating a 3D vascular network through vasculogenesis and angiogenesis using a vascularized microtumor *** a new proof-of-concept in vasculature-on-a-chip,DTB enables seamless contact between the hydrogel and the culture medium in closed microdevices,which is an improved protocol for the fabrication ofmultiorgan ***,we expect it to serve as a promising paradigm for organ-on-a-chip devices for the development of tumor vascularization and drug evaluation in the future preclinical studies.

摘要：Modern medicine is increasingly interested in advanced sensors to detect and analyze biochemical *** sensors based on potentiometric methods are a promising platform for monitoring physiological ions in biological *** semi-implantable devices are mainly based on single-parameter *** semi-implantable electrodes for multiparameter sensing have more restrictions on the electrode size due to biocompatibility considerations,but reducing the electrode surface area could potentially limit electrode *** study developed a semi-implantable device system comprising a multiplexed microfilament electrode cluster(MMEC)and a printed circuit board for real-time monitoring of intra-tissue K^(+),Ca^(2+),and Na^(+)*** electrode surface area was less important for the potentiometric sensing mechanism,suggesting the feasibility of using a tiny fiber-like electrode for potentiometric *** MMEC device exhibited a broad linear response(K^(+):2–32 mmol/L;Ca^(2+):0.5–4 mmol/L;Na^(+):10–160 mmol/L),high sensitivity(about 20–45 mV/decade),temporal stability(>2weeks),and good selectivity(>80%)for the above *** vitro detection and in vivo subcutaneous and brain experiment results showed that the MMEC system exhibits good multi-ion monitoring performance in several complex *** work provides a platform for the continuous real-time monitoring of ion fluctuations in different situations and has implications for developing smart sensors to monitor human health.

摘要：化学取代是有效调节分子电导,产生多通道输运、量子干涉效应和其他机制的关键方法.但分子骨架和侧基之间存在复杂的相互作用,目前仍未被研究清楚.在本工作中,我们结合扫描隧道显微镜裂结实验技术和第一性原理计算方法,深入研究了具有不同σ和π侧基的分子电导.实验结果及理论分析表明,σ侧基的加入引起了分子前线轨道的对称性破缺并加剧了分子内散射,从而导致电导的降低.相反,π侧基引入了额外的电荷传输通道,实现了电荷传输的多通道效应,增加了分子的电导.这些发现为未来分子功能化和分子电子器件的设计提供了坚实的基础.

摘要：Map recognition is an essential data input means of Geographic information System (GIS). How to solve the problems in the procedure, such as recognition of maps with crisscross pipeline networks, classification of buildings and roads, and processing of connected text, is a critical step for GIS keeping high-speed development. In this paper, a new recognition method of pipeline maps is presented, and some common patterns of pipeline connection and component labels are established. Through pattern matching, pipelines and component labels are recognized and peeled off from maps. After this approach, maps simply consist of buildings and roads, which are recognized and classified with fuzzy classification method. In addition, the Double Sides Scan (DSS) technique is also described, through which the effect of connected text can be eliminated.

摘要：磁场触发的催化剂轨道电子自旋排列已成为促进析氧反应的一种有趣而可行的策略.然而,具有强d-d库仑相互作用的高熵合金(HEAs)催化剂中的磁场增强机制尚未得到充分挖掘.在此,我们设计了具有优异软磁性的高熵合金金属片,在微小磁场下表现出显著的磁场增强催化作用,其磁导率可作为评估磁场增强的描述因子.具体地,仅施加50 mT的磁场,(FeCoNi)_(82.5)Cr_(17.5)HEAs的过电位下降就超过了36mV@10 mA cm^(-2).此外,过电位的降低与HEA的磁导率呈线性关系.原位拉曼光谱与理论计算结果表明,施加磁场可显著提高自旋密度,改善催化剂的3d电子与*O自由基的2p轨道之间的自旋相互作用,从而有效降低速率决定步骤(*O→*OOH)的能量障碍,进而促进O-O的形成.